In:
Journal of Applied Toxicology, Wiley, Vol. 38, No. 5 ( 2018-05), p. 656-664
Abstract:
Nanocrystals (NCs) are a potential drug delivery platform. However, existing studies have not investigated whether the nanoscale properties of NCs might lead to toxicity. In this study, monosodium urate NCs were used as a drug model to investigate possible toxicity and to clarify the relationship between particle sizes and NC toxicity. Our research confirmed that NCs were unsafe and that particle sizes were closely related to the degree of NC toxicity.
Type of Medium:
Online Resource
ISSN:
0260-437X
,
1099-1263
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
1475015-6
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