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  • 1
    In: Autophagy, Informa UK Limited, Vol. 12, No. 1 ( 2016-01-02), p. 1-222
    Type of Medium: Online Resource
    ISSN: 1554-8627 , 1554-8635
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2262043-6
    SSG: 12
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  • 2
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-10-07)
    Abstract: Metabolic syndrome (MetS) is characterized by a cluster of signs of metabolic disturbance and has caused a huge burden on the health system. The study aims to explore the prevalence and characteristics of MetS defined by different criteria in the Chinese population. Methods Using the data of the China Hypertension Survey (CHS), a nationally representative cross-sectional study from October 2012 to December 2015, a total of 28,717 participants aged 35 years and above were included in the analysis. The MetS definitions of the International Diabetes Federation (IDF), the updated US National Cholesterol Education Program Adult Treatment Panel III (the revised ATP III), and the Joint Committee for Developing Chinese Guidelines (JCDCG) on Prevention and Treatment of Dyslipidemia in Adults were used. Multivariable logistic regression was used to identify factors associated with MetS. Results The prevalence of MetS diagnosed according to the definitions of IDF, the revised ATP III, and JCCDS was 26.4%, 32.3%, and 21.5%, respectively. The MetS prevalence in men was lower than in women by IDF definition (22.2% vs. 30.3%) and by the revised ATP III definition (29.2% vs. 35.4%), but the opposite was true by JCDCG (24.4%vs 18.5%) definition. The consistency between the three definitions for men and the revised ATP III definition and IDF definition for women was relatively good, with kappa values ranging from 0.77 to 0.89, but the consistency between the JCDCG definition and IDF definition (kappa = 0.58) and revised ATP III definition (kappa = 0.58) was poor. Multivariable logistic regression showed that although the impact and correlation intensity varied with gender and definition, area, age, education, smoking, alcohol use, and family history of cardiovascular disease were factors related to MetS. Conclusions The prevalence and characteristics of the MetS vary with the definition used in the Chinese population. The three MetS definitions are more consistent in men but relatively poor in women. On the other hand, even if estimated according to the definition of the lowest prevalence, MetS is common in China.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2041338-5
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  • 3
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  Journal of Hypertension Vol. 36 ( 2018-10), p. e292-
    In: Journal of Hypertension, Ovid Technologies (Wolters Kluwer Health), Vol. 36 ( 2018-10), p. e292-
    Type of Medium: Online Resource
    ISSN: 0263-6352
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
    detail.hit.zdb_id: 2017684-3
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  • 4
    In: JAMA Psychiatry, American Medical Association (AMA), Vol. 78, No. 11 ( 2021-11-01), p. 1258-
    Type of Medium: Online Resource
    ISSN: 2168-622X
    Language: English
    Publisher: American Medical Association (AMA)
    Publication Date: 2021
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  • 5
    In: Journal of Materials Chemistry A, Royal Society of Chemistry (RSC), Vol. 10, No. 4 ( 2022), p. 2105-2112
    Abstract: Gas-quenching is a promising technique for the up-scalable fabrication of metal halide perovskite solar cells (PSCs). However, it has been challenging to produce high-quality gas-quenched perovskite films without the use of the methylammonium (MA) cation. By employing tetramethylene sulfoxide (TMSO) as a ligand in the precursor solution, high-quality FA 0.9 Cs 0.1 PbI 3 perovskite films have been successfully obtained by gas-quenching. A study on the precursor solution and film-forming process revealed the effect of TMSO on the formation of large-grain films, as well as the critical role of gas-quenching in regulating the intermediate films. The absolute MA-free perovskite device exhibits superior stability over the PSCs obtained with the MACl additive. The fabricated MA- and Br-free PSCs show a power conversion efficiency of 21.3% without any passivation treatment. Moreover, gas-quenching with TMSO enables a wide gas pressure processing window and superior accessibility to low-pressure processing, demonstrating its promising potential in up-scaling manufacturing of high-efficiency MA-free PSCs.
    Type of Medium: Online Resource
    ISSN: 2050-7488 , 2050-7496
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2022
    detail.hit.zdb_id: 2702232-8
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  • 6
    In: BMC Medicine, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2023-06-14)
    Abstract: A workplace-based primary prevention intervention be an effective approach to reducing the incidence of hypertension (HTN). However, few studies to date have addressed the effect among the Chinese working population. We assessed the effect of a workplace-based multicomponent prevention interventions program for cardiovascular disease on reducing the occurrence of HTN through encouraging employees to adopt a healthy lifestyle. Methods In this post hoc analysis of cluster randomized controlled study, 60 workplaces across 20 urban regions in China were randomized to either the intervention group ( n  = 40) or control group ( n  = 20). All employees in each workplace were asked to complete a baseline survey after randomization for obtaining sociodemographic information, health status, lifestyle, etc. Employees in the intervention group were given a 2-year workplace-based primary prevention intervention program for improving their cardiovascular health, including (1) cardiovascular health education, (2) a reasonable diet, (3) tobacco cessation, (4) physical environment promotion, (5) physical activity, (6) stress management, and (7) health screening. The primary outcome was the incidence of HTN, and the secondary outcomes were improvements of blood pressure (BP) levels and lifestyle factors from baseline to 24 months. A mix effect model was used to assess the intervention effect at the end of the intervention in the two groups. Results Overall, 24,396 participants (18,170 in the intervention group and 6,226 in the control group) were included (mean [standard deviation] age, 39.3 [9.1] years; 14,727 men [60.4%]). After 24 months of the intervention, the incidence of HTN was 8.0% in the intervention groups and 9.6% in the control groups [relative risk (RR) = 0.66, 95% CI, 0.58 ~ 0.76, P   〈  0.001]. The intervention effect was significant on systolic BP (SBP) level ( β  =  − 0.7 mm Hg, 95% CI, − 1.06 ~  − 0.35; P   〈  0.001) and on diastolic BP (DBP) level ( β  =  − 1.0 mm Hg, 95% CI, − 1.31 ~  − 0.76; P   〈  0.001). Moreover, greater improvements were reported in the rates of regular exercise [odd ratio (OR) = 1.39, 95% CI, 1.28 ~ 1.50; P   〈  0.001], excessive intake of fatty food (OR = 0.54, 95% CI, 0.50 ~ 0.59; P   〈  0.001), and restrictive use of salt (OR = 1.22, 95% CI, 1.09 ~ 1.36; P  = 0.001) in intervention groups. People with a deteriorating lifestyle had higher rates of developing HTN than those with the same or improved lifestyle. Subgroup analysis showed that the intervention effect of BP on employees with educational attainment of high school above (SBP: β  =  − 1.38/ − 0.76 mm Hg, P   〈  0.05; DBP: β  =  − 2.26/ − 0.75 mm Hg, P   〈  0.001), manual labor workers and administrative worker (SBP: β  =  − 1.04/ − 1.66 mm Hg, P   〈  0.05; DBP: β  =  − 1.85/ − 0.40 mm Hg, P   〈  0.05), and employees from a workplace with an affiliated hospital (SBP: β  =  − 2.63 mm Hg, P   〈  0.001; DBP: β  =  − 1.93 mm Hg, P   〈  0.001) were significantly in the intervention group. Conclusions This post hoc analysis found that workplace-based primary prevention interventions program for cardiovascular disease were effective in promoting healthy lifestyle and reducing the incidence of HTN among employees. Trial registration Chinese Clinical Trial Registry No. ChiCTR-ECS-14004641.
    Type of Medium: Online Resource
    ISSN: 1741-7015
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2131669-7
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  • 7
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Cardiovascular Medicine Vol. 9 ( 2022-8-8)
    In: Frontiers in Cardiovascular Medicine, Frontiers Media SA, Vol. 9 ( 2022-8-8)
    Abstract: The association between reproductive lifespan and risk of hypertension among postmenopausal women is unclear. Methods A total of 94,141 postmenopausal women with a mean age of 64.8 years from the China Hypertension Survey were enrolled at baseline from 2012 to 2015. A standardized questionnaire was used to collect relevant information by well-trained interviewers. Blood pressure and physical examination of the participants were performed by trained medical staff. Logistic regression was used to estimate the odds ratios for hypertension by years of reproductive lifespan. Results The average years of reproductive lifespan in Chinese women was 34.0 years. Women who were longer in reproductive lifespan were more likely to have older age at recruitment, higher body mass index, larger waist circumference, lower mean systolic blood pressure, and higher mean diastolic blood pressure ( p & lt; 0.05). After adjustments, odds ratios (95% confidence interval) for hypertension were 1.035 (0.988–1.085), 1.007 (0.966–1.048), 1.000 (reference), 0.932 (0.899–0.967), and 0.953 (0.909–0.997) for those with reproductive lifespan at ≤ 28, 29–31, 32–34 (reference), 35–37, and ≥ 38 years, respectively, with a significantly inverse association was seen in those with reproductive lifespan at 35–37 and ≥ 38 years. The overall risk of hypertension declined with the increase in reproductive lifespan, and the risk of hypertension was reduced by 1.1% for every 1-year increase in the reproductive lifespan (odds ratio, 0.989; 95% confidence interval, 0985–0.994) per year. The negative association between reproductive lifespan and hypertension was evident among age at recruitment groups, body mass index categories, and education levels, with the strongest association among women aged ≥ 70 years. Positive associations between reproductive lifespan and risk of hypertension were evident among women aged & lt; 60 years, and this association was stronger among current alcohol drinkers. Conclusion Based on the large nationally representative sample, Chinese postmenopausal women with a shorter reproductive lifespan have a higher risk of hypertension.
    Type of Medium: Online Resource
    ISSN: 2297-055X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2781496-8
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  • 8
    In: Metabolites, MDPI AG, Vol. 13, No. 1 ( 2022-12-21), p. 12-
    Abstract: Metabolic syndrome (MetS) is associated with cardiovascular risk, and there are various definitions, but which is most predictive of future cardiovascular disease (CVD) in the Chinese population is still unclear. MetS was defined with the revised ATP III (Third Adult Treatment Panel Report), International Diabetes Federation (IDF), and the Joint Committee for Developing Chinese Guidelines (JCDCG) definitions. Cox regression was used to estimate the hazard risk of cardiovascular disease among 20,888 participants using the Chinese Hypertension Survey (CHS) data. Sensitivity, specificity, and receiver operating characteristic (ROC) curve distance were used to test the ability of three MetS criteria to identify CVD. During an average follow-up of 4.89 years of 20,888 participants, 925 CVD events occurred (stroke, 560; coronary heart disease, 275; and other cardiovascular events, 119). The revised ATP III criteria identified the most individuals with MetS and had the highest prevalence of MetS. In addition, MetS was associated with a high risk of CVD in both men and women, according to three criteria. The highest diagnostic specificity was for IDF in men and JCDCG in women. The revised ATP III criteria had the highest sensitivity and shortest ROC curve distance in both men and women. Although the MetS definitions, including the revised ATP III, IDF, and JCDCG, are all related to the increased risks of CVD, overall, the revised ATP III performs best and is the most recommended for the Chinese population.
    Type of Medium: Online Resource
    ISSN: 2218-1989
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662251-8
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  • 9
    In: JAMA Network Open, American Medical Association (AMA), Vol. 5, No. 12 ( 2022-12-07), p. e2245439-
    Abstract: The prevalence of hypertension is high and still increasing across the world, while the control rate remains low in many countries. Emerging technology, such as telemedicine, may offer additional support to change the unsatisfactory situation. Objective To establish a multicomponent intervention delivered on a web-based telemedicine platform and oriented with the Chinese hypertension management guidelines and to evaluate the effect of the intervention on blood pressure (BP) control for patients with hypertension. Design, Setting, and Participants This cluster randomized clinical trial of a hypertension management program was conducted at 66 community health centers in China from October 1, 2018, to May 31, 2020, with a 12-month follow-up. Patients with hypertension were blinded to randomization and were randomized to either the intervention group or control group. Hypertension was diagnosed at mean systolic BP (SBP) and diastolic BP (DBP) readings higher than 140 and 90 mm Hg or with use of antihypertensive medication. Evaluation of the intervention effect was based on the principle of modified intention to treat. Interventions Multicomponent intervention was delivered on a web-based platform and consisted of a primary prevention program for cardiovascular disease and standardized management for hypertension. Main Outcomes and Measures The primary outcome was the change in BP control rate (SBP and DBP levels & amp;lt;140 and 90 mm Hg, or & amp;lt;130 and 80 mm Hg for patients with diabetes) from baseline to the 12-month follow-up among patients with hypertension in the intervention and control groups. Results A total of 4118 patients (mean [SD] age, 61.6 [9.4] years; 2265 women [55.0%]) were included in the analysis, with 2985 in the intervention group and 1133 in the control group. The BP control rate at baseline was 22.8% in the intervention group and 22.5% in the control group. After 12 months of the intervention, the BP control rate for the intervention group compared with the control group was significantly higher (47.4% vs 30.2%; odds ratio, 1.18; 95% CI, 1.13-1.24; P   & amp;lt; .001). The intervention effect on SBP level was –10.1 mm Hg (95% CI, –11.7 to –8.5 mm Hg; P   & amp;lt; .001) and on DBP level was –1.8 mm Hg (95% CI, –2.8 to –0.8 mm Hg; P   & amp;lt; .001). Conclusions and Relevance Results of this trial showed that a multicomponent intervention delivered on a web-based platform improved BP control rate and lowered BP level more than usual care alone. Such a telemedicine program may provide a new, effective way to treat patients with hypertension in the community and may generate public health benefits across diverse populations. Trial Registration Chinese Clinical Trial Registry Identifier: ChiCTR1800017791
    Type of Medium: Online Resource
    ISSN: 2574-3805
    Language: English
    Publisher: American Medical Association (AMA)
    Publication Date: 2022
    detail.hit.zdb_id: 2931249-8
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  • 10
    In: American Journal of Health Promotion, SAGE Publications
    Abstract: Hypertension-related knowledge, attitude and practice (KAP) of hypertensive patients can affect the awareness, treatment and control of hypertension. However, little attention has been paid to the association between the change of hypertension preventive KAP and blood pressure (BP) control in occupational population using longitudinal data. We assess the effectiveness of a workplace-based multicomponent hypertension intervention program on improving the level of KAP of hypertension prevention, and the association between improvement in KAP and BP control during intervention. Methods From January 2013 to December 2014, workplaces across 20 urban regions in China were randomized to either the intervention group (n = 40) or control group (n = 20) using a cluster randomized control method. All employees in each workplace were asked to complete a cross-sectional survey to screen for hypertension patients. Hypertension patients in the intervention group were given a 2-year workplace-based multicomponent hypertension intervention for BP control. The level of hypertension prevention KAP and BP were assessed before and after intervention in the two groups. Results Overall, 3331 participants (2658 in the intervention group and 673 in the control group) were included (mean [standard deviation] age, 46.2 [7.7] years; 2723 men [81.7%]). After 2-year intervention, the KAP qualified rate was 63.2% in the intervention groups and 50.1% in the control groups (odds ratio = 1.65, 95% CI, 1.36∼2.00, P 〈 .001). Compared with the control group decreased in the qualified rate of each item of hypertension preventive KAP questionnaire, all the items in the intervention group increased to different degrees. The increase of KAP score was associated with the decrease of BP level after intervention. For 1 point increase in KAP score, systolic blood pressure (SBP) decreased by .28 mmHg and diastolic blood pressure (DBP) decreased by .14 mmHg [SBP: β = -.28, 95%CI: −.48∼-.09, P = .004; DBP: β = −.14, 95%CI: −.26∼-.02, P = .024]. SBP and DBP was significantly in manual labor workers (SBP: β = −.34, 95%CI: −.59∼-.09, P = .008; DBP: β = −.23, 95%CI: −.38∼−.08, P = .003), workers from private enterprise, state-owned enterprise (SOE) (SBP: β = −.40, 95%CI: −.64∼−.16, P = .001; DBP: β = −.21, 95%CI: −.36∼−.06, P = .005) and a workplace with an affiliated hospital (SBP: β = −.31, 95%CI: −.52∼−.11, P = .003; DBP: β = −.16, 95%CI: −.28∼−.03, P = .016). The improvement of knowledge (SBP: β = −.29, 95%CI: −.56∼−.02, P = .038; DBP: β = −.12, 95%CI: −.29∼.05, P = .160), as well as attitude (SBP: β = −.71, 95%CI: −1.25∼−.18, P = .009; DBP: β = .18, 95%CI: −.23∼.59, P = .385) and behavior (SBP: β = −.73, 95%CI: −1.22∼−.23, P = .004; DBP: β = −.65, 95%CI: −.97∼−.33, P 〈 .001) was gradually strengthened in relation to BP control. Conclusion This study found that workplace-based multicomponent hypertension intervention can effectively improve the level of hypertension preventive KAP among employees, and the improvement of KAP levels were significantly associated with BP control. Trial Registration Chinese Clinical Trial Registry No. ChiCTR-ECS-14004641.
    Type of Medium: Online Resource
    ISSN: 0890-1171 , 2168-6602
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2134271-4
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