GLORIA

GEOMAR Library Ocean Research Information Access

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • SAGE Publications  (2)
Material
Publisher
  • SAGE Publications  (2)
Language
Years
  • 1
    In: CARTILAGE, SAGE Publications
    Abstract: Intervertebral degenerative disc (IDD) disease is one of the most common clinical conditions causing low back pain. The main objective of this study was to investigate the repair effect of platelet-rich plasma (PRP) and ferulic acid (FA) hydrogel compound on degenerative discs in rats in combination with bioengineering technology, which may provide a strong theoretical basis for the future treatment of IDD. Methods Forty-five male Sprague-Dawley rats were randomly divided into groups A-F; MRI was performed in each group at 0, 4, and 8 weeks after injection; and disc tissues were obtained after executing the animals. The histomorphology, apoptosis, and protein synthesis of intervertebral discs in each group were observed by hematoxylin-eosin, Masson, terminal deoxynucleotidyl transferase dUTP nick end labeling staining, and Western blot. Results The release concentration of all groups reached the peak at 12 hours, and the highest concentration was found in the hydrogel/PRP/FA group at the same time. The MTT assay showed that hydrogel/PRP/FA is well-cytocompatible. The results of animal experiments show that hydrogel/PRP/FA has a good effect on degenerative intervertebral disc in rats. Conclusion PRP/FA-rich hydrogel compound plays an active role in promoting extracellular matrix synthesis, strengthening and repairing degenerated intervertebral discs in rats.
    Type of Medium: Online Resource
    ISSN: 1947-6035 , 1947-6043
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2515870-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  The International Journal of High Performance Computing Applications Vol. 29, No. 4 ( 2015-11), p. 422-436
    In: The International Journal of High Performance Computing Applications, SAGE Publications, Vol. 29, No. 4 ( 2015-11), p. 422-436
    Abstract: Soft errors in scientific computing applications are becoming inevitable with the ever-increasing system scale and execution time, and new technologies that feature increased transistor density and lower voltage. Soft errors can be mainly classified into two categories: bit-flipping error (e.g. 1 becomes −1) in random access memory; and computation error (e.g. 1+1 = 3) in floating point units. Traditionally, bit-flipping error is handled by the Error Correcting Code (ECC) technique, and computation error is dealt with the Triple Modular Redundancy (TMR) method. Note that, ECC cannot handle computation error, while TMR cannot deal with bit-flipping error and is not efficient on handling computation error. To uniformly and efficiently handle both computation and bit-flipping errors in matrix operations, the Algorithm-Based Fault Tolerance (ABFT) method is developed. This paper focuses on the detection of soft errors in the LU Decomposition with Partial Pivoting (LUPP) algorithm, which is widely used in scientific computing applications. First, this paper notes that existing ABFT methods are not adequate to detect soft errors in LUPP in terms of time or space. Then we propose a new ABFT algorithm which can detect soft errors in LUPP both flexible in time and comprehensive in space. Flexible in time means that soft errors can be detected flexibly during the execution instead of only at the end of LUPP, while comprehensive in space indicates that all of the elements in data matrices ( L and U) will be covered for detecting soft errors. To show the feasibility and efficiency of the proposed algorithm, this paper has incorporated it into the implementation of LUPP in the widely used benchmark High Performance Linpack (HPL). Experiment results verify the feasibility of this algorithm: for soft errors injected at various timings and to different elements in LUPP, this algorithm has detected most of the injected errors, which have covered all of the errors that cannot pass the residual check of HPL. Both theoretical overhead analysis and experiments demonstrate that this ABFT algorithm is also very efficient at detecting soft errors in LUPP.
    Type of Medium: Online Resource
    ISSN: 1094-3420 , 1741-2846
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2017480-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...