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  • 1
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Veterinary Ophthalmology Vol. 23, No. 4 ( 2020-07), p. 648-658
    In: Veterinary Ophthalmology, Wiley, Vol. 23, No. 4 ( 2020-07), p. 648-658
    Abstract: To evaluate leptospiral antibody prevalence in 65 horses with ERU and compare outcome in 36 surgically treated eyes (2010‐2015). Procedures Retrospective data analysis of horses with ERU (n = 65). C‐ value calculation with microagglutination assay titer (MAT) results for Leptospira spp. Evaluation of follow‐up data after pars plana vitrectomy (PPV, n = 21 eyes) and suprachoroidal cyclosporine device implantation (SCDI, n = 15 eyes). Differences between groups were statistically analyzed using Fishers exact test, significance set at P   〈  .05. Results Positive leptospiral titers were found in 28/65 blood, 31/65 aqueous humor (AH), and 19/20 vitreal (post‐PPV) samples. The most common intraocular serovars were Leptospira interrogans grippotyphosa , pomona, and bratislava. Intraocular antibody production was suspected in samples of 22 horses ( c ‐values  〉  1). Mean follow‐up of surgical cases was 3.8 years (PPV) and 3.4 years (SCDI). PPV was performed in 21 eyes with positive, SCDI in 15 eyes with negative leptospiral test results. Uveitis recurred less often after PPV (2/21) compared to SCDI (6/15, P  = .04). Retinal detachment occurred after PPV only (5/21, SCDI 0/15, P  = .06), whereas only SCDI‐treated eyes were enucleated (PPV 0/21, SCDI 3/15, P  = .06). Blindness or visual impairment was equally likely to occur in both treatment groups after surgery (PPV 7/21, SCDI 7/15, P  = .5). Conclusions Leptospiral antibody prevalence is high in horses with ERU in Switzerland. Recurrence of uveitis is uncommon following PPV in the present study; an increased risk of retinal detachment exists. Enucleation is more often warranted in horses after SCDI in this study due to a higher uveitis recurrence.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2011043-1
    SSG: 22
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  • 2
    In: Veterinary Ophthalmology, Wiley, Vol. 20, No. 6 ( 2017-11), p. 488-495
    Abstract: To compare the localization and distribution of two different anesthetic fluid volumes around equine cadaver eyes to determine an appropriate volume for a single sub‐Tenon's injection in horses. Procedure A single sub‐Tenon's injection of 2% lidocaine was performed in 10 equine cadaver heads (20 eyes) using two different volumes (7 mL on one side and 10 mL on the opposite side). The posterior circular distribution of the anesthetic was quantified in sagittal, dorsal, and transverse MRI (T2W‐ TSE ) sequences and evaluated independently by three board‐certified radiologists. The distribution of the two fluid volumes was compared via a paired Student's t ‐test. The interobserver reliability was evaluated via a Kruskal–Wallis test. Results Extension of the injection fluid was observed along the dorsal and temporal quadrants of the globe within the subconjunctival space, the anterior and posterior sub‐Tenon's space, and into the muscle sheaths along the extraocular muscles. Accumulation of anesthetic fluid directly surrounding the optic nerve was detected in three of 20 cadaver eyes. Circular distribution of the 7 and 10 mL anesthetic volumes was not significantly different ( P = 0.849). More retrograde leakage of the anesthetic was observed using the 10 mL volume. Evaluation of interobserver reliability revealed no significant differences between observers ( P = 0.21–0.92). Conclusions Sub‐Tenon's anesthesia can have potential as an alternative to retrobulbar anesthesia for ophthalmic surgeries in equines. A 7‐ to 10‐mL injection volume should be appropriate based on the results of this study. The distribution of the anesthetic solution in live tissues, the clinical effects, and the potential for complications will have to be evaluated in vivo .
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2011043-1
    SSG: 22
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  • 3
    In: Veterinary Ophthalmology, Wiley, Vol. 21, No. 1 ( 2018-01), p. 66-75
    Abstract: To evaluate the most common bacterial pathogens associated with septic keratitis in veterinary patients from Switzerland. The second objective was to analyze antibiotic susceptibility test results of the identified bacterial pathogens. The third objective was to evaluate potential breed predispositions to septic keratitis. Procedures Two hundred and fifty‐five cultures and antibiotic susceptibility reports from dogs, cats, and horses with septic keratitis that were presented to the University of Zurich Veterinary Medical Teaching Hospital between 2009 and 2013 were reviewed. Odds ratios for the risk of having a septic keratitis were estimated for all dog and cat breeds compared to the general nonbrachycephalic hospital population. Results Ninety‐six, 29, and 31 positive cultures were obtained from 89 canine, 28 feline, and 29 equine eyes, respectively. Repeat sampling accounted for the differences in numbers. Negative culture results were obtained in 50, 31, and 18 cases. Staphylococci and streptococci accounted for 66% of the isolates in dogs and 80% of the isolates in cats and horses. Staphylococcus spp . had a higher percentage of fluoroquinolone‐resistant isolates compared to previous reports. Brachycephalic breeds had elevated odds ratios for the presence of septic keratitis. Conclusion Identified bacterial pathogens and their prevalence as well as the elevated odds ratios for septic keratitis in brachycephalics are roughly consistent with previous studies. Based on systemic breakpoint data, resistance to commonly used topical antibiotics, including the second‐generation fluoroquinolones, was found.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2011043-1
    SSG: 22
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  • 4
    In: Veterinary Ophthalmology, Wiley, Vol. 22, No. 4 ( 2019-07), p. 462-469
    Abstract: To screen a closed herd of the Old Kladruber Horses ( OKH ) for the prevalence of ocular disorders and report normal ocular variations. Animals studied Two hundred and sixty‐one horses, 122 Old Kladruber Gray Horses, and 139 Old Kladruber Black Horses owned by the National Stud Farm Kladruby nad Labem, Czech Republic, were included in the study with signalment and pedigree information recorded. Procedures Bilateral ocular examination of manually restrained horses was performed in a darkened environment by a single examiner ( RA ), using a portable slit‐lamp biomicroscope, direct ophthalmoscope, and monocular indirect ophthalmoscopy using a Finnoff transilluminator and 20 D condensing lens. Fluorescein testing was performed when indicated. Results The animal ages ranged from 3 months to 27 years (mean 7.82 years, median 6 years). The gender ratio (males:females) was 109:152. Ophthalmological abnormalities were found in 133 (50.96%) horses; with right and left eyes affected equally. The most common abnormalities were cataract formation (35 horses), iris hyperpigmentation (29 horses), alterations in corpora nigra size (26 horses), nonsenile vitreal degeneration (24 horses), linear keratopathy (11 horses), corneal stromal haze (nine horses) and corneal subepithelial punctate opacities (nine horses). The most frequent variations of normal ocular anatomy were posterior lenticular suture lines (222 horses), tapetal hypoplasia (95 horses) resulting in a multi‐colored tapetal fundus (31 horses), nuclear sclerosis (48 horses), and senile vitreal degeneration (30 horses). Conclusions Ocular disorders were relatively common in OKH , but typically not vision threatening and not interfering with the quality of life.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2011043-1
    SSG: 22
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