In:
The Journal of Bone and Joint Surgery. British volume, British Editorial Society of Bone & Joint Surgery, Vol. 80-B, No. 3 ( 1998-05), p. 520-526
Abstract:
We studied peridural fibrosis in 16 dogs after laminectomies at the L2, L4 and L6 levels. They received either a free fat graft, a biodegradable mechanical barrier (polyethylene oxide (PEO)/polybutylene terephthalate (PBT) copolymer), or no treatment. The animals were killed after 4, 12, 26 and 52 weeks. Histomorphometry showed extensive and consistent peridural fibrosis in control and PEO/PBT groups. Fat grafts produced significantly less fibrous tissue, but the presence of the fat graft in the bony defect prevented closure. Degradation of the PEO/PBT barrier resulted in the formation of more fibrous tissue. We conclude that up to one year a free fat graft is effective in reducing the amount of peridural scarring.
Type of Medium:
Online Resource
ISSN:
0301-620X
,
2044-5377
DOI:
10.1302/0301-620X.80B3.0800520
Language:
English
Publisher:
British Editorial Society of Bone & Joint Surgery
Publication Date:
1998
detail.hit.zdb_id:
2697480-0
detail.hit.zdb_id:
2039886-4
Permalink