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  • Van de Borne, Sigrid  (3)
  • 2015-2019  (3)
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  • 2015-2019  (3)
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  • 1
    In: BJU International, Wiley, Vol. 123, No. 5A ( 2019-05)
    Abstract: To assess clinical follow‐up data over 24 months, comparing the use of a curved vs straight stylet in patients undergoing sacral neuromodulation using the standardized tined lead implantation technique. Patients and Methods We conducted a single tertiary‐centre, prospective study between August 2013 and June 2015 involving 40 patients with overactive bladder and 15 with non‐obstructive urinary retention refractory to first‐line treatment. The primary outcome was successful tined lead procedure according to intention‐to‐treat analyses at 12 and 24 months. The secondary outcome was number of optimal electrode configurations during programming. Statistical analysis was performed using plain non‐parametric tests for numerical and categorical data. Results Successful tined lead procedures were achieved in 33 of 35 patients (94%) implanted with the curved stylet compared with 13 of 20 patients (65%) implanted with the straight stylet ( P = 0.005). Intention‐to‐treat analyses at 12 and 24 months showed success rates of 94% and 91%, respectively, in the curved stylet group vs 65% and 45%, respectively, in the straight stylet group ( P = 0.002 and P 〈 0.001). In the curved stylet group, 60% and 25% of the electrode configurations were considered optimal and poor, respectively, vs 40% and 37%, respectively, in the straight stylet group ( P 〈 0.001). Conclusions The use of the standardized implantation technique with the curved stylet led to more successful tined lead procedures, better success rates after 2 years of follow‐up and a greater number of optimal electrode configurations when compared to use of the straight stylet.
    Type of Medium: Online Resource
    ISSN: 1464-4096 , 1464-410X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2019983-1
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  • 2
    In: Neurourology and Urodynamics, Wiley, Vol. 38, No. 2 ( 2019-02), p. 801-808
    Abstract: Sacral neuromodulation (SNM) is an established minimally invasive therapy for functional disorders of the pelvic organs in which electrodes are stimulated in proximity of the sacral spinal nerves. Reprogramming of the electrodes is regularly required and is based on the sensory response. This study assesses the repeatability of a pelvic chart and grading system to enable a more objective assessment of the sensory response upon electrode stimulation. Material and Methods In 26 SNM patients, with OAB or NOUR, assessment of the sensory response was done using the sensory threshold (ST) and a pelvic chart with 1 cm 2 coordinates, each coordinate corresponding with a dermatome and location of sensation (LoS). A grading system was developed based upon the ST and LoS. Repeatability of ST was assessed using a two‐way mixed effects, absolute agreement, single rater/measurement intraclass correlation coefficient (ICC), and displayed using a correlation and Bland Altman plot. Repeatability of dermatomes, LoS, and grading system was assessed using kappa correlation coefficient. Results On average, 1.55 ± 0.85 coordinates were used to point out the area where the stimulation was perceived. The mean amount of coordinates between the area pointed at during the first and second measurement was 0.47 ± 0.74. ST showed excellent repeatability (ICC 0.93, 95%CI 0.90‐0.94, P   〈  0.001). Dermatomes, LoS and grading system showed a substantial to almost perfect agreement ( κ  = 0.740‐0.833, P   〈  0.001). Conclusions The pelvic chart and grading system, using the sensory response upon electrode stimulation, are repeatable tools and can be used to assist in follow up and troubleshooting of SNM patients.
    Type of Medium: Online Resource
    ISSN: 0733-2467 , 1520-6777
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1500793-5
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  • 3
    Online Resource
    Online Resource
    Journal of Biological Methods ; 2016
    In:  Bladder Vol. 3, No. 2 ( 2016-05-09), p. e23-
    In: Bladder, Journal of Biological Methods, Vol. 3, No. 2 ( 2016-05-09), p. e23-
    Abstract: Objectives: Evaluate sensation in the urethra during voiding and the possible role of visual and audible impulses, in young healthy men.Methods: In 10 healthy volunteers, 2 non-invasive uroflowmetries were done at desire to void and sensations felt during voiding were evaluated by questionnaire. Influence of  visual and audible input was studied by performing a uroflowmetry  while wearing blindfold eye patches and ear cups + earplugs.Results: All  participants reported sensation of start of voiding, all but one of voiding stop. All felt clearly urine passage in the urethra  and 8 had a sensation of warmth in the urethra. Visual and audible blocking gave lowering in grades of sensation. To start voiding took a significantly longer time. It became difficult for some men  to determine accurately when the flow stopped.Conclusions: Voiding elicited different types of sensation in the urethra in healthy young men. The sensation was independent of the uroflowmetry parameters. Blocking visual and audible signals influenced the sensory and voiding process.
    Type of Medium: Online Resource
    ISSN: 2327-2120
    Language: Unknown
    Publisher: Journal of Biological Methods
    Publication Date: 2016
    detail.hit.zdb_id: 3035057-8
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