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  • 1
    Online Resource
    Online Resource
    THE MODEL SCREENING PREECLAMPSIA AT 11+0 TO 13+6 WEEKS OF GESTATION
    Hue University of Medicine and Pharmacy ; 2015
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objective: Screening preeclampsia at 11+0-13+6 gestational by combine maternal characteristics, MAP, PAPP-A and UtA-PI. Materials and methods: Prospective screening study for preeclampsia in pregnant attending their first hospital visit at 11-13 weeks 6 of gestation. The performance of screening for PE and GH by combinations of maternal characteristics, uterine artery with the lowest pulsatility index (L-PI), mean arterial pressure (MAP) and serum PAPP-A was determined. Results: Of 2,998 patients with complete outcome data, there were 3.74% of hypertension disorder, and 2.84% cases of pre-eclampsia. The study show a poor results screening for PE by maternal factors only. In screening for PE by combine maternal factors, MAP and L-PI, the estimated detection rates were 18,2% and 45,5% for HG, 45,6% and 57,9% for late PE at a fixed false positive rate of 5% and 10%, respectively.For early PE, in screening by combine maternal characteristics, L-PI, MAP and serum PAPP-A, the the estimated detection rates were 81,8% and 90,9% at at a fixed false positive rate of 5% and 10%, respectively. Conclusion: Effective prediction of early PE can be achieved at 11–13+6 weeks’ gestation by combine maternal characteristics, L-PI, MAP and serum PAPP-A. Key words: preeclampsia; gestational hypertension; screening; PAPP-A, UtA-PI, MAP
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2015.4_5.22
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2015
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  • 2
    Online Resource
    Online Resource
    MATERNAL SERUM PAPP-A LEVELS AT 11+0 TO 13+6 WEEKS OF GESTATION IN THE PREDICTION OF HYPERTENSION DISORDER
    Hue University of Medicine and Pharmacy ; 2015
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objective: To detect maternal serum PAPP-A levels at 11-13 weeks 6 day of gestation in pregnancies who subsequently develop pre-eclampsia and to evaluating the role of these screening PAPP-A in the prediction of pre-eclampsia. Materials and methods: Prospective screening study for preeclampsia in pregnant attending their first hospital visit at 11-13 weeks 6 of gestation. The performance of screening for PE by serum PAPP-A and free βhCG were determined. Results: Of 2,998 patients with complete outcome data, there were 3.74% of hypertension disorder, and 2.84% cases of pre-eclampsia. free βhCG levels were no different significantly in pregnancy who developed pre-eclampsia compared to the control group. PAPP-A levels were significantly lower in pregnants who developed early pre-eclampsia (0.653 MoM) and late pre-eclampsia (0.744 MoM) compared to the control group (1.039 MoM).In screening for PE by combinematernal factors and PAPP-A,at false positive rate of 5%, the estimateddetection rates were 36.4% and the detection rates were 54.6%, at at false positive rate of 10%. Conclusion: Low PAPP-A levels are associated with the development of preeclampsia; however, it should be combined with other tests to increase effectiveness of hypertension disorder screening at the first trimester. Key words: preeclampsia; gestational hypertension; screening; PAPP-A.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2015.4_5.20
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2015
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  • 3
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    Online Resource
    GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
    Hindawi Limited ; 2019
    In:  International Journal of Endocrinology Vol. 2019 ( 2019-03-13), p. 1-6
    Details
    In: International Journal of Endocrinology, Hindawi Limited, Vol. 2019 ( 2019-03-13), p. 1-6
    Abstract: This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who are administered either gonadotropin-releasing hormone agonist (GnRHa) or human chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination (IUI) cycles. A prospective randomized comparative study was conducted at Hue University Hospital in Vietnam. A total of 197 infertile women were randomly assigned to receive either GnRHa trigger ( n = 98 cycles) or hCG trigger ( n = 99 cycles) for ovulation trigger. Patients returned for ultrasound monitoring 24 hours after IUI to confirm ovulation. A clinical pregnancy was defined as the presence of gestational sac with fetal cardiac activity. There was no difference in ovulation rates in either group receiving GnRHa or hCG trigger for ovulation. Biochemical and CPR were higher in patients who received hCG (28.3% and 23.2%) versus GnRHa (14.3% and 13.3%) ( p = 0.023 , OR 0.42, 95 % CI = 0.21 − 0.86 and p = 0.096 , OR 0.51, 95 % CI = 0.24 − 1.07 , respectively). After adjusting for body mass index (BMI) and infertility duration, there was no difference in CPR between the two groups (OR 0.58, 95% CI 0.27-1.25, p = 0.163 ). In conclusion, the use of the GnRHa to trigger ovulation in patients undergoing ovulation induction may be considered in patients treated with IUI.
    Type of Medium: Online Resource
    ISSN: 1687-8337 , 1687-8345
    URL: Article
    DOI: 10.1155/2019/2487067
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2502951-4
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  • 4
    Online Resource
    Online Resource
    Community-based prevalence versus hospital-based incidence of genital Human Papillomavirus infection in Central Vietnam
    Journal of Infection in Developing Countries ; 2018
    In:  The Journal of Infection in Developing Countries Vol. 12, No. 07 ( 2018-07-31), p. 568-572
    Details
    In: The Journal of Infection in Developing Countries, Journal of Infection in Developing Countries, Vol. 12, No. 07 ( 2018-07-31), p. 568-572
    Abstract: Introduction: This study aims to determine the genital HPV prevalence in reproductive-age women in Thua Thien Hue Province and comparison with HPV incidence in Hue University Hospital, Vietnam. Methodology: Cross-sectional study on 1,034 women of reproductive age from 11 communes/wards of three districts representing three different geographic areas of Thua Thien Hue Province, Vietnam. The hospital-based group included 102 women with cervicitis and/or abnormal Pap smear result coming to Hue University Hospital. Extracting DNA from cervical samples, performing the real-time PCR for detecting HPV and the reverse dot-blot assay for HPV typing in HPV positive cases. Results: In community, HPV prevalence was 0.9%. Mean-age of HPV positive group was 37.9 ± 6.2 years. The detected low-risk types were 6 and 11; high-risk types include 16, 18, 33, 45, 52, and 58. Single-type infection was found in 66.7% of cases. In hospital-based group, 41.2% of women have been infected with HPV, 6 different HPV types were detected. HPV18 was the most frequent high-risk type (33.3%), followed by HPV16 (15.1%); HPV6 was the most frequent among low-risk HPV types (31.2%). Single-type infection rate was 33,3%; 2 and 3 types co-infections were 28,6% and 38.1%, respectively. Conclusions: Routine screening of high-risk HPV infection in women with symptomatic gynecologic infection and/or abnormal Pap smear appears to be benefit in early detection and prevention of cervical cancer, due to the high incidence of HPV infection.
    Type of Medium: Online Resource
    ISSN: 1972-2680
    URL: Article
    DOI: 10.3855/jidc.10297
    Language: Unknown
    Publisher: Journal of Infection in Developing Countries
    Publication Date: 2018
    detail.hit.zdb_id: 2394024-4
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  • 5
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    Online Resource
    Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam
    Korean Endocrine Society ; 2018
    In:  Endocrinology and Metabolism Vol. 33, No. 4 ( 2018), p. 447-
    Details
    In: Endocrinology and Metabolism, Korean Endocrine Society, Vol. 33, No. 4 ( 2018), p. 447-
    Type of Medium: Online Resource
    ISSN: 2093-596X , 2093-5978
    URL: Article
    DOI: 10.3803/EnM.2018.33.4.447
    Language: English
    Publisher: Korean Endocrine Society
    Publication Date: 2018
    detail.hit.zdb_id: 2802452-7
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  • 6
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    Online Resource
    Antenatal dexamethasone use and respiratory distress in late preterm infants: results from first Vietnamese matched cohort study
    Springer Science and Business Media LLC ; 2021
    In:  BMC Pregnancy and Childbirth Vol. 21, No. 1 ( 2021-12)
    Details
    In: BMC Pregnancy and Childbirth, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-12)
    Abstract: Respiratory distress syndrome (RDS) is one of the leading causes of early neonatal morbidity and mortality in late preterm infants (LPIs) worldwide. This matched cohort study aimed to assess how the antenatal dexamethasone use affect the respiratory distress (RD) proportion in preterm newborns between 34 0/7 weeks and 36 6/7 weeks of gestation. Methods This was a prospective cohort study on 78 women with singleton pregnancy who were in threatened preterm birth and had not received prior dexamethasone, who were admitted between 34 0/7 weeks and 36 6/7 weeks at Hue University of Medicine and Pharmacy Hospital from June 2018 to May 2020. The matched control group without dexamethasone use included 78 pregnant women diagnosed with threatened late preterm births who were at similar gestational ages and estimated fetal weights as the treatment group. The treatment group received 6 mg intramuscular dexamethasone every 12 h for a total of 4 doses or until delivery. Primary outcome was the rate of neonatal RD. Secondary neonatal outcomes included the need for respiratory support, neonatal intensive care unit (NICU) admission, hypoglycemia, necrotizing enterocolitis, intraventricular hemorrhage, and neonatal death. Statistical analyses were performed by using SPSS software, version 26.0. Results The proportion of RD in LPI was significantly lower in the treatment group than in the matched control group (10.3% vs. 23.1%, respectively), adjusted Odds Ratio [aOR] 0.29; 95% confidence interval [CI] 0.10 – 0.83 and p = 0.021. Neonatal hypoglycemia was more common in the dexamethasone group than in the matched group (25.6% vs. 12.8%, respectively; aOR, 2.59; 95% CI, 1.06 – 6.33; p = 0.037). There were no significant between-groups differences in the incidence of respiratory support, NICU admission or length of hospital stay. Conclusions Administration of antenatal dexamethasone to women at risk for late preterm birth could help to lower the proportion of respiratory distress in late preterm infants.
    Type of Medium: Online Resource
    ISSN: 1471-2393
    URL: Article
    DOI: 10.1186/s12884-021-04019-6
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2059869-5
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  • 7
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    Online Resource
    ROLE OF FETAL MONITORING IN THE SECOND STAGE OF LABOR
    Hue University of Medicine and Pharmacy ; 2011
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objectives: (1) to investigate the progression of the second stage of labor, (2) to evaluation of outcome of labor base on the form of the fetal monitoring. Materials and methods: Crosse sectional describe of 379 pregnant women with vertex presentation, singleton pregnancy, at term, normal pelvis, and the fetal weight was estimated to be medium according to Vietnamese size, applying the distribution in fetal heart form according to Melchior and the distribution in stage of labor according to PEOPLE. Study period: from June 2009 to December 2009. Results: The average of the age was 27.2 ± 12 years. Gestation age (weeks) was 39.1 ± 1.2. Nulliparous women was 55.67% (211 women), and multiparous women was 44.3% (168 women). 58.4% of those whose fetus was at 0 position according to Delle’s distribution. The position of the fetus was left occiput anterior which was majority, 68%. The total duration of second stage was 88 ± 25 minutes. Fetal heart rate: Type 1 was 33.7%, type 2 was 45.5%. In the type 1, when the active phase stretch to 90 minutes, the fetus was well response. In the type 2, the second stage cannot stretch as long as these, if it lasts longer then 60minutes, not even 83.37% but just also 28.5% was at good condition, should stopped labor immediately. The mean Apgar score will 〈 7 at 1st minutes, 40 % and 50% in type 3 and 4 respectively. Conclusions: Left occiput anterior was 68%. Total duration of the second stage of labor was 88 ± 25 minutes. Type 0, 1, 2, 3 and 4 of fetal heart rate were 3.3%; 33.7%; 45.5%; 12.1% and 7.4% respectively. Apgar score 〈 7 at 1st minutes with type 0, 3 and 4 after 30 minutes for the forceful, and with type 1 after 90 minutes for that.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2011.1.17
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2011
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  • 8
    Online Resource
    Online Resource
    Psychological Burden in Couples with Infertility and Its Association with Sexual Dysfunction
    Springer Science and Business Media LLC ; 2020
    In:  Sexuality and Disability Vol. 38, No. 1 ( 2020-03), p. 123-133
    Details
    In: Sexuality and Disability, Springer Science and Business Media LLC, Vol. 38, No. 1 ( 2020-03), p. 123-133
    Type of Medium: Online Resource
    ISSN: 0146-1044 , 1573-6717
    URL: Article
    DOI: 10.1007/s11195-019-09612-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2018684-8
    SSG: 5,2
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  • 9
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    Online Resource
    ASSESSMENT OF EFFICACY OF LAPAROSCOPIC SURGERY IN TUBAL-PERITONEAL INFERTILITY
    Hue University of Medicine and Pharmacy ; 2012
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objective: To determine some causes and affecting factors of tubal-peritoneal infertility. To assess the efficacy of laparoscopy in treating tubal-peritoneal infertility. Methods: Prospective study in 126 patients with tubal-peritoneal infertility. Results: Main causes of tubal infertility: Infection: 42.7%, history of operation: 25.6%, endometriosis: 12.8% and other causes and undetermined causes: 18.9%. 79.5% patients have patent tubes through hysterosalpingography. The rate of false obstructed tube through hysterosalpingography was 7.1%. The rate of intrauterine pregnancy after laparoscopy was 21.4%. This rate was associated with the stage of tubal lesons and the highest rate was in the first stage (68.0%). Nobody can get pregnant with the tubal lesions in the third and fourth stage or severe adheson. Conclusion: Main causes of tubal infertility are infection, history of operation and endometriosis. The rate of intrauterine pregnancy and patent tubes in this study is equivalent to some national and international studies. This rate is associated with the stage of tubal le-sions and the degree of tubal adhesion.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2012.1.13
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2012
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  • 10
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    Online Resource
    Validation of the Vietnamese Translation Version of the Female Sexual Function Index in Infertile Patients
    Oxford University Press (OUP) ; 2020
    In:  Sexual Medicine Vol. 8, No. 1 ( 2020-03-01), p. 57-64
    Details
    In: Sexual Medicine, Oxford University Press (OUP), Vol. 8, No. 1 ( 2020-03-01), p. 57-64
    Abstract: The Female Sexual Function Index (FSFI) is regarded as a self-administered screening questionnaire for assessing the presence of any type of sexual dysfunction. Aim The aim of this study was to investigate the psychometric properties of the Vietnamese translation version of the Female Sexual Function Index (VN-FSFI) in a sample of infertile Vietnamese women. Methods An existing Vietnamese translated-FSFI version was used as a first-step approach to back-translate into English. Based on the comparison of the original English version and the back-translation script, a modified version of the FSFI was revised. This version was evaluated for “content validity” by a panel of 3 experts and for “face validity” by a pilot study that was based on its results to refine to reach the last Vietnamese FSFI version (VN-FSFI version). A cross-sectional survey to investigate psychometric reliability and validity of the last VN-FSFI version was conducted with 271 infertile Vietnamese women from January 2017 through February 2018, at a hospital located in a central region of Vietnam. Construct validity was evaluated by principal component analysis using varimax rotation and factor analysis. Reliability studies on internal consistency (Cronbach’s alpha coefficient, domain inter-correlations, and domain-total correlations) and on test-retest (Intraclass correlation coefficient). Main Outcome Measure Construct validity and the reliability of the VN-FSFI version. Results Based on principal component analysis, a 5-factor model was established, consisting of arousal/orgasm, satisfaction, pain, lubrication, and desire that explained 72.32% of the total variance. The factorial structure supported to 6 retrieved domains that corresponded to the original version. The Cronbach’s alpha coefficients were 0.92 for the total scale and 0.72−0.89 for the domains. Domain inter-correlations ranged from 0.36−0.73 and domain-total correlation coefficients ranged from 0.67−0.84. Test-retest correlation coefficients over 2−4 weeks were 0.97 (P & lt; .001) for the total scale and 0.84−0.96 for the domains. Conclusion With good psychometric properties, which are almost similar to the original English version, this Vietnamese translation version of the Female Sexual Function Index (VN-FSFI version) was proved to be a valid and reliable instrument to measure multidimensional aspects of sexual function in infertile Vietnamese women.
    Type of Medium: Online Resource
    ISSN: 2050-1161
    URL: Article
    DOI: 10.1016/j.esxm.2019.09.004
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2020
    detail.hit.zdb_id: 2734882-9
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