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  • SAGE Publications  (4)
  • Tazu Bonger, Zelalem  (4)
  • 1
    Online Resource
    Online Resource
    Preterm Nutrition and Clinical Outcomes
    SAGE Publications ; 2020
    In:  Global Pediatric Health Vol. 7 ( 2020-01), p. 2333794X2093785-
    Details
    In: Global Pediatric Health, SAGE Publications, Vol. 7 ( 2020-01), p. 2333794X2093785-
    Abstract: Background. In low-income countries, preterm nutrition is often inadequately addressed. The aim of the study was to assess the patterns of feeding and associated clinical outcomes of preterm neonates admitted to neonatal intensive care units in Ethiopia. Method. This was a multicenter, prospective study. Infants’ clinical characteristics at birth, daily monitoring of feeding history, and weight measurements were collected. An outcome assessment was completed at 28 days. Result. For this analysis, 2560 infants (53% male) were eligible. The mean (SD) gestational age was 33.1 (2.2) weeks. During the hospital stay the proportion of infants on breast milk only, preterm formula, term formula, and mixed feeding was 58%, 27.4%, 1.6%, and 34.1%, respectively. Delay in enteral feeding was associated with increased risk of death (odds ratio [OR] = 1.92, 95% confidence interval [CI] = 1.33-2.78; P 〈 .001) and (OR = 5.06, 95% CI = 3.23-7.87; P 〈 .001) for 1 to 3 and 4 to 6 days of delay in enteral feeding, respectively, after adjusting for possible confounders. The length of delay in enteral feeding was associated with increased risk of hypoglycemia (OR = 1.2, 95% CI = 1.1-1.2; P = .005). The mortality rate was lower in hospitals providing preterm formula more often ( P = .04). Half of the infants continued losing weight at the time of discharge. Conclusion. Delayed enteral feeding significantly increases the risk of mortality before discharge and hypoglycemia in preterm infants in resource-limited settings. Ensuring adequate nutritional support of preterm infants is highly needed.
    Type of Medium: Online Resource
    ISSN: 2333-794X , 2333-794X
    URL: Article
    DOI: 10.1177/2333794X20937851
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2785531-4
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Disparity in Birth Size of Ethiopian Preterm Infants in Comparison to International INTERGROWTH-21st Data
    SAGE Publications ; 2020
    In:  Global Pediatric Health Vol. 7 ( 2020-01), p. 2333794X2097348-
    Details
    In: Global Pediatric Health, SAGE Publications, Vol. 7 ( 2020-01), p. 2333794X2097348-
    Abstract: Background. Patterns of fetal growth are largely influenced by environmental, nutritional, and socioeconomic factors more than differences in populations. The aim of this study was to assess anthropometric measurements of Ethiopian preterm infants at birth and compare the results with the international INTERGROWTH-21st data. Patients and methods. We analyzed anthropometric data on live-born singleton preterm infants enrolled in a hospital-based multicenter study of illness in preterm infants (SIP). Eligible newborns with gestational age of 28-36 weeks were included. Gestational age (GA) and sex-specific mean and standard deviations (SD), 10th, 50th, 90th, centile values for birth weight, length and head circumference (HC) were calculated and compared with INTERGROWTH-21st data. Result. A total of 2763 preterm infants were included in the study, 54% were male. The prevalence of small for GA (SGA) ( 〈 10th percentile) and large for GA (LGA) ( 〉 90th percentile) were 10.8% and 9.9%, respectively. In all 3 parameters, the mean values of boys were higher than of girls. Birth weight centiles were comparable to international averages at lower GA, then after GA of 32 weeks the 10th, 50th, and 90th centile values were 100-500 g less than the international averages. The head circumference centiles were mostly comparable, and the 90th centile values were greater than the international averages across the GA and in both sexes. Conclusion. The infants’ birth weights were smaller at higher GA, which may indicate maternal undernutrition in the third trimester of pregnancy. Strengthening antenatal nutrition counseling and providing nutrition supplementation might improve the birth weight.
    Type of Medium: Online Resource
    ISSN: 2333-794X , 2333-794X
    URL: Article
    DOI: 10.1177/2333794X20973484
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2785531-4
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Hypothermia in Preterm Newborns: Impact on Survival
    SAGE Publications ; 2020
    In:  Global Pediatric Health Vol. 7 ( 2020-01), p. 2333794X2095765-
    Details
    In: Global Pediatric Health, SAGE Publications, Vol. 7 ( 2020-01), p. 2333794X2095765-
    Abstract: Background. Globally, prematurity is the leading cause of neonatal mortality, and hypothermia is one of its contributing factors. The goal of this study was to determine the association between hypothermia and mortality. Methods. A prospective, multi-center, descriptive clinical study was conducted in 5 hospitals in Ethiopia. Axillary temperatures were taken at the time of admission to the newborn intensive care units (NICU) and followed during the NICU stay. Results. A total of 3852 premature neonates ( 〈 37 weeks) were admitted to the NICUs from July 2016 to May 2018. Of these infants, 1109 (28.8%) died and 2991 (79.6%) had hypothermia. Hypothermia was associated with perinatal asphyxia (89.5%), RDS (86.2%), and resuscitation at birth (82.7%). Admission temperatures in preterm newborns were inversely associated with mortality and morbidity. Conclusion. Hypothermia at admission is associated with neonatal mortality in premature neonates in Ethiopia. RDS and perinatal asphyxia were the main factors associated with hypothermia. The very high prevalence and association with mortality warrants quality improvement interventions.
    Type of Medium: Online Resource
    ISSN: 2333-794X , 2333-794X
    URL: Article
    DOI: 10.1177/2333794X20957655
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2785531-4
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    Online Resource
  • 4
    Online Resource
    Online Resource
    Hyperbilirubinemia in Preterm Infants Admitted to Neonatal Intensive Care Units in Ethiopia
    SAGE Publications ; 2020
    In:  Global Pediatric Health Vol. 7 ( 2020-01), p. 2333794X2098580-
    Details
    In: Global Pediatric Health, SAGE Publications, Vol. 7 ( 2020-01), p. 2333794X2098580-
    Abstract: Background. Hyperbilirubinemia is prevalent and protracted in preterm infants. This study assessed the pattern of hyperbilirubinemia in preterm infants in Ethiopia. Methods. This study was part of multi-centered prospective, cross-sectional, observational study that determined causes of death among preterm infants. Jaundice was first identified based on clinical visual assessment. Venous blood was then sent for total and direct serum bilirubin level measurements. For this study, a total serum bilirubin level ≥5 mg/dL was taken as the cutoff point to diagnose hyperbilirubinemia. Based on the bilirubin level and clinical findings, the final diagnoses of hyperbilirubinemia and associated complications were made by the physician. Result. A total of 4919 preterm infants were enrolled into the overall study, and 3852 were admitted to one of the study’s newborn intensive care units. Of these, 1779 (46.2%) infants were diagnosed with hyperbilirubinemia. Ten of these (0.6%) developed acute bilirubin encephalopathy. The prevalence of hyperbilirubinemia was 66.7% among the infants who were less than 28 weeks of gestation who survived. Rh incompatibility ( P = .002), ABO incompatibility ( P = .0001), and sepsis ( P = .0001) were significantly associated with hyperbilirubinemia. Perinatal asphyxia ( P-value = 0.0001) was negatively associated with hyperbilirubinemia. Conclusion. The prevalence of hyperbilirubinemia in preterm babies admitted to neonatal care units in Ethiopia was high. The major risk factors associated with hyperbilirubinemia in preterm babies in this study were found to be ABO incompatibility, sepsis, and Rh isoimmunization.
    Type of Medium: Online Resource
    ISSN: 2333-794X , 2333-794X
    URL: Article
    DOI: 10.1177/2333794X20985809
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2785531-4
    Location Call Number Limitation Availability
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    Online Resource
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