In:
Journal of Child Neurology, SAGE Publications, Vol. 29, No. 7 ( 2014-07), p. 980-982
Kurzfassung:
Although the “face of the giant panda” sign on magnetic resonance imaging (MRI) is traditionally considered to be characteristic of Wilson disease, it has also been reported in other metabolic disorders. This study describes the characteristic “giant panda” sign on MRI in a child with Leigh disease. The diagnosis was based on the history of neurological regression; examination findings of oculomotor abnormalities, hypotonia, and dystonia; raised serum lactate levels; and characteristic brain stem and basal ganglia signal changes on MRI. The midbrain and pontine tegmental signal changes were consistent with the “face of the giant panda and her cub” sign. In addition to Wilson disease, metabolic disorders such as Leigh disease should also be considered in the differential diagnosis of this rare imaging finding.
Materialart:
Online-Ressource
ISSN:
0883-0738
,
1708-8283
DOI:
10.1177/0883073813484968
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2014
ZDB Id:
2068710-2
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