GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Perception–Action Integration Is Altered in Functional Movement Disorders
    Wiley ; 2023
    In:  Movement Disorders Vol. 38, No. 8 ( 2023-08), p. 1399-1409
    Details
    In: Movement Disorders, Wiley, Vol. 38, No. 8 ( 2023-08), p. 1399-1409
    Abstract: Although functional neurological movement disorders (FMD) are characterized by motor symptoms, sensory processing has also been shown to be disturbed. However, how the integration of perception and motor processes, essential for the control of goal‐directed behavior, is altered in patients with FMD is less clear. A detailed investigation of these processes is crucial to foster a better understanding of the pathophysiology of FMD and can systematically be achieved in the framework of the theory of event coding (TEC). Objective The aim was to investigate perception–action integration processes on a behavioral and neurophysiological level in patients with FMD. Methods A total of 21 patients and 21 controls were investigated with a TEC‐related task, including concomitant electroencephalogram (EEG) recording. We focused on EEG correlates established to reflect perception–action integration processes. Temporal decomposition allowed to distinguish between EEG codes reflecting sensory (S‐cluster), motor (R‐cluster), and integrated sensory–motor processing (C‐cluster). We also applied source localization analyses. Results Behaviorally, patients revealed stronger binding between perception and action, as evidenced by difficulties in reconfiguring previously established stimulus–response associations. Such hyperbinding was paralleled by a modulation of neuronal activity clusters, including reduced C‐cluster modulations of the inferior parietal cortex and altered R‐cluster modulations in the inferior frontal gyrus. Correlations of these modulations with symptom severity were also evident. Conclusions Our study shows that FMD is characterized by altered integration of sensory information with motor processes. Relations between clinical severity and both behavioral performance and neurophysiological abnormalities indicate that perception–action integration processes are central and a promising concept for the understanding of FMD. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
    Type of Medium: Online Resource
    ISSN: 0885-3185 , 1531-8257
    URL: Issue
    URL: Article
    DOI: 10.1002/mds.v38.8
    DOI: 10.1002/mds.29458
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2041249-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Processing of embedded response plans is modulated by an interplay of frontoparietal theta and beta activity
    American Physiological Society ; 2022
    In:  Journal of Neurophysiology Vol. 128, No. 3 ( 2022-09-01), p. 543-555
    Details
    In: Journal of Neurophysiology, American Physiological Society, Vol. 128, No. 3 ( 2022-09-01), p. 543-555
    Abstract: Even simple actions like opening a door require integration/binding and flexible reactivation of different motor elements. Yet, the neural mechanisms underlying the processing of such “embedded response plans” are largely elusive, despite theoretical frameworks, such as the theory of event coding, describing the involved cognitive processes. In a sample of n = 40 healthy participants, we combine time-frequency decomposition and various beamforming methods to examine the neurophysiological dynamics of such action plans, with special emphasis on the interplay of theta and beta frequency activity during the processing of these plans. We show that the integration and rule-guided reactivation of embedded response plans is modulated by a complex interplay of theta and beta activity. Pretrial beta-band activity (BBA) is related to different functional neuroanatomical structures that are activated in a consecutive fashion. Enhanced preparatory activity is positively associated with higher binding-related BBA in the precuneus/parietal areas, indicating that activity in the precuneus/parietal cortex facilitates the execution of an embedded action sequence. Increased preparation subsequently leads to reduced working memory retrieval demands. A cascading pattern of interactions between pretrial and within-trial activity indicates the importance of preparatory brain activity. The study shows that there are multiple roles of beta and theta oscillations associated with different functional neuroanatomical structures during the integration and reactivation of motor elements during actions. NEW & NOTEWORTHY Even simple actions like opening a door require integration/binding and flexible reactivation of different motor elements. Yet, the neural mechanisms underlying the processing of such “embedded response plans” are largely elusive. The study shows that there are multiple roles of beta and theta oscillations associated with different functional neuroanatomical structures during the integration and reactivation of motor elements during actions.
    Type of Medium: Online Resource
    ISSN: 0022-3077 , 1522-1598
    URL: Article
    DOI: 10.1152/jn.00537.2021
    RVK:
    XA 10000 ; XA 552555
    Language: English
    Publisher: American Physiological Society
    Publication Date: 2022
    detail.hit.zdb_id: 80161-6
    detail.hit.zdb_id: 1467889-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Theta Activity Dynamics during Embedded Response Plan Processing in Tourette Syndrome
    MDPI AG ; 2023
    In:  Biomedicines Vol. 11, No. 2 ( 2023-01-28), p. 393-
    Details
    In: Biomedicines, MDPI AG, Vol. 11, No. 2 ( 2023-01-28), p. 393-
    Abstract: Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder. Because motor signs are the defining feature of GTS, addressing the neurophysiology of motor processes is central to understanding GTS. The integration of voluntary motor processes is subject to so-called “binding problems”, i.e., how different aspects of an action are integrated. This was conceptualized in the theory of event coding, in which ‘action files’ accomplish the integration of motor features. We examined the functional neuroanatomical architecture of EEG theta band activity related to action file processing in GTS patients and healthy controls. Whereas, in keeping with previous data, behavioral performance during action file processing did not differ between GTS and controls, underlying patterns of neural activity were profoundly different. Superior parietal regions (BA7) were predominantly engaged in healthy controls, but superior frontal regions (BA9, BA10) in GTS indicated that the processing of different motor feature codes was central for action file processing in healthy controls, whereas episodic processing was more relevant in GTS. The data suggests a cascade of cognitive branching in fronto-polar areas followed by episodic processing in superior frontal regions in GTS. Patients with GTS accomplish the integration of motor plans via qualitatively different neurophysiological processes.
    Type of Medium: Online Resource
    ISSN: 2227-9059
    URL: Article
    DOI: 10.3390/biomedicines11020393
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2720867-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Unsigned surprise but not reward magnitude modulates the integration of motor elements during actions
    Springer Science and Business Media LLC ; 2023
    In:  Scientific Reports Vol. 13, No. 1 ( 2023-04-03)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2023-04-03)
    Abstract: It seems natural that motor responses unfold smoothly and that we are able to easily concatenate different components of movements to achieve goal-directed actions. Theoretical frameworks suggest that different motor features have to be bound to each other to achieve a coherent action. Yet, the nature of the “glue” (i.e., bindings) between elements constituting a motor sequence and enabling a smooth unfolding of motor acts is not well understood. We examined in how far motor feature bindings are affected by reward magnitude or the effects of an unsigned surprise signal. We show that the consistency of action file binding strength is modulated by unsigned surprise, but not by reward magnitude. On a conceptual and theoretical level, the results provide links between frameworks, which have until now not been brought into connection. In particular, theoretical accounts stating that only the unexpectedness (surprisingness) is essential for action control are connected to meta-control accounts of human action control.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-023-32508-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2615211-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Tourette syndrome as a motor disorder revisited – Evidence from action coding
    Elsevier BV ; 2021
    In:  NeuroImage: Clinical Vol. 30 ( 2021), p. 102611-
    Details
    In: NeuroImage: Clinical, Elsevier BV, Vol. 30 ( 2021), p. 102611-
    Type of Medium: Online Resource
    ISSN: 2213-1582
    URL: Article
    DOI: 10.1016/j.nicl.2021.102611
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2701571-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Distinct Brain-Oscillatory Neuroanatomical Architecture of Perception-Action Integration in Adolescents With Tourette Syndrome
    Elsevier BV ; 2021
    In:  Biological Psychiatry Global Open Science Vol. 1, No. 2 ( 2021-08), p. 123-134
    Details
    In: Biological Psychiatry Global Open Science, Elsevier BV, Vol. 1, No. 2 ( 2021-08), p. 123-134
    Type of Medium: Online Resource
    ISSN: 2667-1743
    URL: Article
    DOI: 10.1016/j.bpsgos.2021.04.003
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 3094992-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Increased scale-free and aperiodic neural activity during sensorimotor integration—a novel facet in Tourette syndrome
    Oxford University Press (OUP) ; 2021
    In:  Brain Communications Vol. 3, No. 4 ( 2021-10-01)
    Details
    In: Brain Communications, Oxford University Press (OUP), Vol. 3, No. 4 ( 2021-10-01)
    Abstract: Tourette syndrome is a common neurodevelopmental disorder defined by multiple motor and phonic tics. Tics in Tourette syndrome resemble spontaneously occurring movements in healthy controls and are therefore sometimes difficult to distinguish from these. Tics may in fact be mis-interpreted as a meaningful action, i.e. a signal with social content, whereas they lack such information and could be conceived a surplus of action or ‘motor noise’. These and other considerations have led to a ‘neural noise account’ of Tourette syndrome suggesting that the processing of neural noise and adaptation of the signal-to-noise ratio during information processing is relevant for the understanding of Tourette syndrome. So far, there is no direct evidence for this. Here, we tested the ‘neural noise account’ examining 1/f noise, also called scale-free neural activity as well as aperiodic activity, in n = 74 children, adolescents and adults with Tourette syndrome and n = 74 healthy controls during task performance using EEG data recorded during a sensorimotor integration task. In keeping with results of a previous study in adults with Tourette syndrome, behavioural data confirmed that sensorimotor integration was also stronger in this larger Tourette syndrome cohort underscoring the relevance of perceptual-action processes in this disorder. More importantly, we show that 1/f noise and aperiodic activity during sensorimotor processing is increased in patients with Tourette syndrome supporting the ‘neural noise account’. This implies that asynchronous/aperiodic neural activity during sensorimotor integration is stronger in patients with Tourette syndrome compared to healthy controls, which is probably related to abnormalities of GABAergic and dopaminergic transmission in these patients. Differences in 1/f noise and aperiodic activity between patients with Tourette syndrome and healthy controls were driven by high-frequency oscillations and not lower-frequency activity currently discussed to be important in the pathophysiology of tics. This and the fact that Bayesian statistics showed that there is evidence for the absence of a correlation between neural noise and clinical measures of tics, suggest that increased 1/f noise and aperiodic activity are not directly related to tics but rather represents a novel facet of Tourette syndrome.
    Type of Medium: Online Resource
    ISSN: 2632-1297
    URL: Article
    DOI: 10.1093/braincomms/fcab250
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 3020013-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Increased perception-action binding in Tourette syndrome
    Oxford University Press (OUP) ; 2020
    In:  Brain Vol. 143, No. 6 ( 2020-06-01), p. 1934-1945
    Details
    In: Brain, Oxford University Press (OUP), Vol. 143, No. 6 ( 2020-06-01), p. 1934-1945
    Abstract: Gilles de la Tourette syndrome is a multifaceted neurodevelopmental disorder characterized by multiple motor and vocal tics. Research in Tourette syndrome has traditionally focused on the motor system. However, there is increasing evidence that perceptual and cognitive processes play a crucial role as well. Against this background it has been reasoned that processes linking perception and action might be particularly affected in these patients with the strength of perception-action binding being increased. However, this has not yet been studied experimentally. Here, we investigated adult Tourette patients within the framework of the ‘Theory of Event Coding’ using an experimental approach allowing us to directly test the strength of perception-action binding. We included 24 adult patients with Tourette syndrome and n = 24 healthy control subjects using a previously established visual-motor event file task with four levels of feature overlap requiring repeating or alternating responses. Concomitant to behavioural testing, EEG was recorded and analysed using temporal signal decomposition and source localization methods. On a behavioural level, perception-action binding was increased in Tourette patients. Tic frequency correlated with performance in conditions where unbinding processes of previously established perception-action bindings were required with higher tic frequency being associated with stronger perception-action binding. This suggests that perception-action binding is intimately related to the occurrence of tics. Analysis of EEG data showed that behavioural changes cannot be explained based on simple perceptual or motor processes. Instead, cognitive processes linking perception to action in inferior parietal cortices are crucial. Our findings suggest that motor or sensory processes alone are less relevant for the understanding of Tourette syndrome than cognitive processes engaged in linking and restructuring of perception-action association. A broader cognitive framework encompassing perception and action appears well suited to opening new routes for the understanding of Tourette syndrome.
    Type of Medium: Online Resource
    ISSN: 0006-8950 , 1460-2156
    URL: Article
    DOI: 10.1093/brain/awaa111
    RVK:
    XA 10000
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2020
    detail.hit.zdb_id: 1474117-9
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Perception-action integration in young age—A cross-sectional EEG study
    Elsevier BV ; 2021
    In:  Developmental Cognitive Neuroscience Vol. 50 ( 2021-08), p. 100977-
    Details
    In: Developmental Cognitive Neuroscience, Elsevier BV, Vol. 50 ( 2021-08), p. 100977-
    Type of Medium: Online Resource
    ISSN: 1878-9293
    URL: Article
    DOI: 10.1016/j.dcn.2021.100977
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2572271-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Neuropharmacological Interventions and Event File Coding in Gilles de la Tourette Syndrome
    Hogrefe Publishing Group ; 2019
    In:  Zeitschrift für Neuropsychologie Vol. 30, No. 4 ( 2019-12-01), p. 223-229
    Details
    In: Zeitschrift für Neuropsychologie, Hogrefe Publishing Group, Vol. 30, No. 4 ( 2019-12-01), p. 223-229
    Abstract: Abstract. Alterations in the integration of perception and action have been proposed as a core cognitive characteristic of GTS. However, to date it is unknown how neuropharmacological interventions used to treat GTS affect the neural systems related to perception and action integration. Here, we introduce an integrated neuropsychopharmacological perspective to address this question. Specifically, we consider the relevant abnormalities in cortico-striato-thalamo-cortical circuits. Furthermore, we highlight how GTS medication might affect the integration of perception and action in the context of event file coding.
    Type of Medium: Online Resource
    ISSN: 1016-264X , 1664-2902
    URL: Article
    DOI: 10.1024/1016-264X/a000270
    Language: English
    Publisher: Hogrefe Publishing Group
    Publication Date: 2019
    detail.hit.zdb_id: 2091184-1
    SSG: 5,2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...