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  • 1
    Online Resource
    Online Resource
    Universitas Airlangga ; 2020
    In:  Folia Medica Indonesiana Vol. 56, No. 3 ( 2020-09-23), p. 203-
    In: Folia Medica Indonesiana, Universitas Airlangga, Vol. 56, No. 3 ( 2020-09-23), p. 203-
    Abstract: Specific ABO blood type was reported to the higher risk of having overweight and obesity. The laters had also been suggested to correlate to blood pressure. Here we studied blood type and blood pressure amongst seemingly healthy university students of IIKBW, Kediri to understand their correlations to the body mass index (BMI). The blood typing (ABO typing, Eryclone®) and blood pressure (automated digital sphygmomanometer) of 74 male and 76 female were measured in duplicate accordingly. The BMI was analysed from the student’s body weight and height using a digital balance and a microtoise staturemeter, respectively. Data were analysed using SPSS 17 with p 〈 0.05 level of significance. There were 18.7% students have A blood type, 31.3% students were B type, 44% were O and 6.0% with AB blood type. There were 30.7% students with obesity, 18% overweight, 36% normal weight and 15.3% underweight. There were 4.7% had a hypertension, 28.7% pre-hypertension, and 66.7% were normal. No significant correlations found between BMI or the blood pressure to any specific ABO blood type, except between the blood pressure and the AB blood type (r=-0.179, p=0.03). However, there was a significant correlation between BMI and blood pressure (r=0.327, p=0.000). We observed no significant associations between any specific ABO blood type with the BMI and blood pressure. However, high blood pressures amongst students with obesity were found. Males were more common to suffer from obesity and high blood pressure than females.
    Type of Medium: Online Resource
    ISSN: 2599-056X , 2355-8393
    Language: Unknown
    Publisher: Universitas Airlangga
    Publication Date: 2020
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  • 2
    Online Resource
    Online Resource
    Universitas Nahdlatul Ulama Surabaya ; 2022
    In:  Indonesian Journal of Medical Laboratory Science and Technology Vol. 4, No. 2 ( 2022-10-30), p. 148-156
    In: Indonesian Journal of Medical Laboratory Science and Technology, Universitas Nahdlatul Ulama Surabaya, Vol. 4, No. 2 ( 2022-10-30), p. 148-156
    Abstract: Bay leaf extract (Syzygiun polianthum) is one herbal elemnt that may be used to lessen liver function issues, lessen symptops of nausea, vomiting, discomfort and improve adherence and the effectiveness of tuberculossi treatment. The objective of this study was to determine the effect of bay leaf (Syzygium polyanthum) extract on antioxidant activity, Malondialdehyde (MDA) levels, and liver histopathology of ethambutol-induced Wistar rats. This research is a laboratory experiment. Antioxidant activity of Bay Leaf Extract was evaluated by comparing vitamin C with spectrophotometry methods. White Wistar rats were separated into 6 groups and uset to test the lebel of MDA and livers histopathology. Group 1 serves as the control group and received DMSO (placebo); Group 2 was received ethambutol 50mg/kg BW; Group 3 was received ethambutol and silymarine with dose 50mh/kg BW. Group 4-6 had been given ethambutol and extra ethanol extract of bay leaves of 75,150, dan 300mg/kg BW, respectively. The results of the spectrophotometry showed that the Bay Leaf Extract had antioxidant activity comparable to that of vitamin C, with an IC50 of 11.4 g ± (4.4%). One-Way ANOVA test results obtained p = 0.002 (p 〈 0.05) while the Kruskal-Wallis test results obtained the Asymp. Sig value 0.105 〉 0.05. There was a significance difference in each group’s MDA levels (p=0.002). Although there was no significant difference in the liver histopathology of treated rats (p 〉 0.05). While bay leaf extract significantly lowers MDA levels in ethambutol-induced Wistar rats, it has no discernible impact on the liver histopathology of ethambutol-induced Wistar rats. Bay leaf extract possesses antioxidant activity comparable to vitamin C.
    Type of Medium: Online Resource
    ISSN: 2656-9825 , 2684-6748
    URL: Issue
    Language: Unknown
    Publisher: Universitas Nahdlatul Ulama Surabaya
    Publication Date: 2022
    detail.hit.zdb_id: 3120894-0
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  • 3
    In: International Journal of Information and Education Technology, EJournal Publishing, Vol. 12, No. 6 ( 2022), p. 476-484
    Abstract: Technological developments have a positive impact on humans to improve their abilities in line with innovations in the field of education which are increasing day by day. One of them is by increasing intelligence through collaboration between humans and technology called augmented intelligence. In this study augmented intelligence is applied to assist humans in studying human anatomy by utilizing augmented reality technology to perform motion tracking that can control 3D assets to follow it. The anatomy learning platform that was built was named AIVE (Artificial Intelligence on Virtual Education) with an architectural system consisting of a frontend for interface needs and AR platform development, there is also a backend for streaming databases and AI algorithms. Measurement of satisfaction and interest based on the PIECES framework is also carried out to determine the user’s response to the platform being built. The results show a satisfaction level of 4.12 and an interest of 4.10 which means that users are satisfied and interested in the human anatomy tracking platform that is accessed via smartphones.
    Type of Medium: Online Resource
    ISSN: 2010-3689
    Language: Unknown
    Publisher: EJournal Publishing
    Publication Date: 2022
    detail.hit.zdb_id: 2719094-8
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  • 4
    In: Bali Medical Journal, DiscoverSys, Inc., Vol. 11, No. 2 ( 2022-08-24), p. 985-993
    Abstract: Background: Targeting PCSK9 by maintaining hemodynamic shear stress stability has been shown in several studies to reduce LDL-C, arterial plaque formation, and PCSK9 expression in atherosclerotic cardiovascular disease. Genome editing with CRISPR-associated regularly interspersed short palindromic repeats (CRISPR/Cas9) have therapeutic potential for atherosclerotic cardiovascular disease. This study aims to evaluate the role of CRISPR/Cas9 in targeting PCSK9 as an effective therapeutic and long-term effect on atherosclerotic vascular disease. Methods: The method used in this study summarizes the article by looking for keywords that have been determined in the title and abstract. The authors used official guidelines from Science Direct, PubMed, the American College of Cardiology, Google Scholar, and PERKI to select full-text articles published within the last decade, prioritizing searches within the last five years. Results: CRISPR/Cas9 deletion of PCSK9 in mouse models reduces LDL-C, Plaque accumulation in the arteries, and PCSK9 expression. Furthermore, CRISPR/Cas9 deletion in PCSK9 saves the stability of Hemodyanimc shear stress to control the PCSK9 expression that causes Atherosclerotic cardiovascular disease. Conclusion: PCSK9 targeting by CRISPR/Cas9 deletion effectively reduces LDL-C, plaque buildup in the arteries, and PCSK9 expression. However, more research is needed to determine its side effects and safety.
    Type of Medium: Online Resource
    ISSN: 2302-2914 , 2089-1180
    Language: Unknown
    Publisher: DiscoverSys, Inc.
    Publication Date: 2022
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  • 5
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 11, No. F ( 2023-02-05), p. 1-12
    Abstract: BACKGROUND: Sickle cell anemia is a hereditary globin chain condition that leads to hemolysis and persistent organ damage. Chronic hemolytic anemia, severe acute and chronic pain, and end-organ destruction occur throughout the lifespan of sickle cell anemia. SCD is associated with a higher risk of mortality. Genome editing with CRISPR-associated regularly interspersed short palindromic repeats (CRISPR/Cas9) have therapeutic potential for sickle cell anemia thala. AIM: This research aimed to see if using CRISPR/Cas9 to target β-globin gene is an effective therapeutic and if it has a long-term effect on Sickle Cell Anemia. METHODS: The method used in this study summarizes the article by looking for keywords that have been determined in the title and abstract. The authors used official guidelines from Science Direct, PubMed, Google Scholar, and Journal Molecular Biology to select full-text articles published within the last decade, prioritizing searches within the past 10 years. RESULTS: CRISPR/Cas9-mediated genome editing in clinical trials contributes to α-globin gene deletion correcting β-thalassemia through balanced α- and β-globin ratios and inhibiting disease progression. CONCLUSION: HBB and BCL11A targeting by CRISPR/Cas9 deletion effectively inactivate BCL11A, a repressor of fetal hemoglobin production. However, further research is needed to determine its side effects and safety.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2023
    detail.hit.zdb_id: 3032255-8
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  • 6
    Online Resource
    Online Resource
    Universitas Airlangga ; 2021
    In:  Folia Medica Indonesiana Vol. 56, No. 3 ( 2021-01-14), p. 203-
    In: Folia Medica Indonesiana, Universitas Airlangga, Vol. 56, No. 3 ( 2021-01-14), p. 203-
    Abstract: Specific ABO blood type was reported to the higher risk of having overweight and obesity. The laters had also been suggested to correlate to blood pressure. Here we studied blood type and blood pressure amongst seemingly healthy university students of IIKBW, Kediri to understand their correlations to the body mass index (BMI). The blood typing (ABO typing, Eryclone®) and blood pressure (automated digital sphygmomanometer) of 74 male and 76 female were measured in duplicate accordingly. The BMI was analysed from the student’s body weight and height using a digital balance and a microtoise staturemeter, respectively. Data were analysed using SPSS 17 with p 〈 0.05 level of significance. There were 18.7% students have A blood type, 31.3% students were B type, 44% were O and 6.0% with AB blood type. There were 30.7% students with obesity, 18% overweight, 36% normal weight and 15.3% underweight. There were 4.7% had a hypertension, 28.7% pre-hypertension, and 66.7% were normal. No significant correlations found between BMI or the blood pressure to any specific ABO blood type, except between the blood pressure and the AB blood type (r=-0.179, p=0.03). However, there was a significant correlation between BMI and blood pressure (r=0.327, p=0.000). We observed no significant associations between any specific ABO blood type with the BMI and blood pressure. However, high blood pressures amongst students with obesity were found. Males were more common to suffer from obesity and high blood pressure than females.
    Type of Medium: Online Resource
    ISSN: 2599-056X , 2355-8393
    Language: Unknown
    Publisher: Universitas Airlangga
    Publication Date: 2021
    Location Call Number Limitation Availability
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  • 7
    Online Resource
    Online Resource
    Politeknik Kesehatan Kerta Cendekia ; 2022
    In:  Community Service Journal of Indonesia Vol. 4, No. 2 ( 2022-10-28), p. 64-69
    In: Community Service Journal of Indonesia, Politeknik Kesehatan Kerta Cendekia, Vol. 4, No. 2 ( 2022-10-28), p. 64-69
    Abstract: The ongoing Covid 19 pandemic in Indonesia has an impact on psychosocial conditions for everyone. The elderly is a vulnerable group for COVID-19, the elderly experiences a decrease in the ability of body functions both physically and psychologically of a physiological nature. Decreased body function in the elderly is caused by changes in muscle morphology and degenerative diseases, these can cause health problems in the elderly. The implementation of this community service activity aims to teach Cadres and the elderly about Cognitive Behavior Therapy as an effort to increase the independence of the elderly during the COVID-19 pandemic. The method used in this community service activity is to provide training and education health services. This activity was carried out during April-May 2022 which was attended by 12 health cadres and 22 residents in RW 06 Wonokromo Village, Surabaya. The results show that the activity has achieved success according to the success indicators that have been set, namely as many as 12 health cadres were successfully recruited; average attendance is 100%, participants participate in activities enthusiastically, knowledge of cadres after training and residents after counseling increases significantly.
    Type of Medium: Online Resource
    ISSN: 2684-7884 , 2774-4027
    URL: Issue
    Language: Unknown
    Publisher: Politeknik Kesehatan Kerta Cendekia
    Publication Date: 2022
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  • 8
    Online Resource
    Online Resource
    Universitas Nahdlatul Ulama Surabaya ; 2022
    In:  Journal of Health Community Service Vol. 2, No. 3 ( 2022-09-30), p. 88-93
    In: Journal of Health Community Service, Universitas Nahdlatul Ulama Surabaya, Vol. 2, No. 3 ( 2022-09-30), p. 88-93
    Abstract: The Covid-19 pandemic, which began to hit the world in 2020, has increased human awareness regarding the importance of paying attention to aspects of their health. Disaster mitigation is a strategy or effort to minimize the impact when a disaster occurs, both natural and social disasters that may occur in the future. Delivery of disastermitigation activities can be carried out in various ways, including through education, counseling, and training, both conventional and modern. Knowledge related to disaster mitigation should be given to the community starting from basic education. According to the above background, we realize that it is very important to develop awareness andpursuit of disaster preparedness in Islamic boarding schools as soon as possible. This community service activity program has been held at the Assalafi Al-Fithrah Islamic Boarding School in Surabaya which was held on May 21-22 2022 This community service activity is carried out offline with the method of presentation, discussion andquestion and answer, and training. The research was conducted using a quasi-experimental design with a pre-test and post-test approach. The participants for this community service activity are students from the Assalafi Al-Fithrah Islamic boarding school, Surabaya. Results: The results of the pretest and posttest questionnaires showedthat there were differences before and after socialization with a P value of 〈 0.05. This shows that good knowledge makes participants apply health protocols well. Dissemination of disaster mitigation socialization has a good impact and shows significant results on the results of the pretest and post-test
    Type of Medium: Online Resource
    ISSN: 2798-0804 , 2798-1169
    URL: Issue
    Language: Unknown
    Publisher: Universitas Nahdlatul Ulama Surabaya
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 9
    Online Resource
    Online Resource
    Universitas Nahdlatul Ulama Surabaya ; 2022
    In:  SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT 2021 Vol. 1, No. 1 ( 2022-01-25), p. 627-633
    In: SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT 2021, Universitas Nahdlatul Ulama Surabaya, Vol. 1, No. 1 ( 2022-01-25), p. 627-633
    Abstract: Corona Virus Disease 2019, atau Covid-19 adalah penyakit menular ini disebabkan oleh Corona Virus jenis SARS-COV-2, yang pertama kali muncul di Wuhan, China pada Desember 2019. Jumlah kasus kematian di Indonesia meningkat dan belum terdapat tanda-tanda akan menurun. Pondok pesantren (ponpes) adalah tempat berkumpulnya banyak orang dimana rentan terjadi penularan penyakit terutama Covid-19. Pondok Pesantren (Ponpes) KHA Wahid Hasyim Bangil dinobatkan sebagai Ponpes Tangguh Kebal COVID-19 oleh Polres Pasuruan. Ponpes merupakan center of exellence dalam aspek moral-agama, moral-kesehatan, maupun moral-ekonomi bagi masyarakat sekitar ponpes. Pemberdayaan kesehatan masyarakat berbasis ponpes dipandang akan memudahkan menjangkau masyarakat tradisional. Berdasarkan uraian tersebut, dibuatlah sebuah upaya komprehensif untuk pemberdayaan kesehatan berbasis pondok pesantren. Kegiatan kali ini berfokus pada peningkatan pengetahuan tentang herbal sederhana yang bermanfaat sebagai suplemen pendamping terapi COVID-19 (webinar). Kegiatan ini bertujuan mendukung pemulihan kesehatan dan pemberdayaan ekonomi masyarakat di sekitar pondok pesantren yang tidak tersentuh program-program pemerintah.
    Type of Medium: Online Resource
    ISSN: 2964-9145 , 2964-9137
    Language: Unknown
    Publisher: Universitas Nahdlatul Ulama Surabaya
    Publication Date: 2022
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