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  • Hindawi Limited  (3)
  • Sun, Zhiwei  (3)
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  • Hindawi Limited  (3)
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  • 1
    Online Resource
    Online Resource
    A Typical Basalt Platform Landslide: Mechanism and Stability Prediction of Xiashan Landslide
    Hindawi Limited ; 2021
    In:  Advances in Civil Engineering Vol. 2021 ( 2021-4-2), p. 1-14
    Details
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2021 ( 2021-4-2), p. 1-14
    Abstract: The Xiashan landslide, which is classified as a typical basalt platform landslide, is the most massive landslide in Zhejiang Province, China. Once sliding occurs, it will pose a severe threat to the life and property of downstream residents and the nearby section of Hangzhou-Taizhou Expressway. On the basis of the geological conditions, present situation, and latest monitoring data of the landslide, this study finds that rainfall is the main influencing factor, and the creep mode is the main prediction mode of its subsequent deformation. The rainfall statistics of the landslide area in the past 30 years show that the rainfall and rainfall frequency in the landslide area display an increasing trend. The probability of heavy rain with rainfall intensity of 100–250 mm/day in the landslide area is very high. On this basis, combined with the numerical analysis method, a finite element model of the slope considering rainfall and groundwater conditions is constructed to analyze the causes and failure mechanism of this landslide comprehensively. Results indicate that the maximum tensile stress at the top of the trailing edge under the natural state is 5.10 MPa, which is very close to the saturated tensile strength of rock mass. Thus, tensile cracks are easily generated and developed, thereby causing the failure mode to be the hydraulic driving type. Also, with the increase in rainfall intensity, the slope plastic strain increases and the slope plastic zone develops and extends until it is completely penetrated. When the rainfall intensity is more than 200 mm/day, the slope safety factor is close to unity, and the slope approaches a failure condition. Therefore, the landslide should be controlled through water treatment and integrated with engineering measures.
    Type of Medium: Online Resource
    ISSN: 1687-8094 , 1687-8086
    URL: Article
    DOI: 10.1155/2021/6697040
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2449760-5
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    Online Resource
  • 2
    Online Resource
    Online Resource
    MiR-455-5p Suppresses the Progression of Prostate Cancer by Targeting CCR5
    Hindawi Limited ; 2019
    In:  BioMed Research International Vol. 2019 ( 2019-04-11), p. 1-8
    Details
    In: BioMed Research International, Hindawi Limited, Vol. 2019 ( 2019-04-11), p. 1-8
    Abstract: Accumulated evidence indicates that miR-455-5p functions as tumor suppressor in the progression of various cancers. However, the mechanism through which miR-455-5p influences the tumorigenesis of human prostate cancer (PCa) remains undetermined. In this study, reanalysis of data obtained from the Memorial Sloan Kettering Cancer Center showed that miR-455-5p can be used as biomarker for PCa diagnosis and predictor of poor prognosis. Functional assays indicated that miR-455-5p overexpression could suppress cellular proliferation, inhibit tumor growth, and trigger apoptosis by activating and cleaving caspase 3. We experimentally verified that miR-455-5p negatively regulated the C–C motif chemokine receptor 5 (CCR5). Overall, our data demonstrate that miR-455-5p suppressed PCa cellular proliferation and induced cell apoptosis by downregulating CCR5. Thus, miR-455-5p may be considered a new therapeutic strategy for PCa.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    URL: Article
    DOI: 10.1155/2019/6394784
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2698540-8
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  • 3
    Online Resource
    Online Resource
    Attribute Set-Based Boolean Keyword Search over Encrypted Personal Health Records
    Hindawi Limited ; 2021
    In:  Security and Communication Networks Vol. 2021 ( 2021-12-23), p. 1-13
    Details
    In: Security and Communication Networks, Hindawi Limited, Vol. 2021 ( 2021-12-23), p. 1-13
    Abstract: A personal health record (PHR) is an electronic application which enables patients to collect and share their health information. With the development of cloud computing, many PHR services have been outsourced to cloud servers. Cloud computing makes it easier for patients to manage their personal health records and makes it easier for doctors and researchers to share and access this information. However, due to the high sensitivity of PHR, a series of security protections are needed to protect them, such as encryption and access control. In this article, we propose an attribute set-based Boolean keyword search scheme, which can realize fine-grained access control and Boolean keyword search over encrypted PHR. Compared with the existing attribute-based searchable encryption, our solution can not only improve the flexibility in specifying access policies but also perform Boolean keyword search, which can meet the needs of large-scale PHR users. Furthermore, we simulate our scheme, and the experimental results show that our scheme is practical for PHR systems in cloud computing.
    Type of Medium: Online Resource
    ISSN: 1939-0122 , 1939-0114
    URL: Article
    DOI: 10.1155/2021/9023141
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2415104-X
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