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  • Wiley  (172)
  • Sun, Zhe  (172)
  • 1
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    Online Resource
    Pathogenicity and fungicide sensitivity of Pythium and Phytopythium spp. associated with soybean in the Huang‐Huai region of China
    Wiley ; 2020
    In:  Plant Pathology Vol. 69, No. 6 ( 2020-08), p. 1083-1092
    Details
    In: Plant Pathology, Wiley, Vol. 69, No. 6 ( 2020-08), p. 1083-1092
    Abstract: Pythium and Phytopythium spp. cause seed decay, damping off, and root rot in soybean, wheat, and many other crops. However, their diversity and importance as pathogens, particularly in different crop rotation systems, are largely unknown. A survey was conducted in the Huang‐Huai region, one of the main areas of soybean–wheat rotation farming in China. In 2016–2018, we collected 300 soybean seedlings and 150 field soil samples from several representative locations, and identified 26 Pythium and 6 Phytopythium spp. from 212 isolates, based on internal transcribed spacer 2 (ITS2) and cytochrome oxidase subunit 1 sequences. The pathogenicity of these isolates was evaluated by growing soybean and wheat seeds in dishes and pots containing oomycete cultures. We found that 12 Pythium spp. (but no Phytopythium spp.) showed high pathogenicity on soybean and/or wheat, and nine of them (75%) were highly pathogenic on both crops. Among the nine species, Pythium spinosum ,  Pythium ultimum , Pythium species 1 (tentatively designated as ‘Candidatus Pythium huanghuaiense ’), Pythium aphanidermatum , and Pythium myriotylum were highly abundant among all isolates (15%, 10%, 9%, 8%, and 5%, respectively). Nine species were selected for testing of sensitivity to the fungicides metalaxyl and mefenoxam. The EC 50 values were all less than 10 μg/ml, indicating little resistance. Minimum inhibitory concentration values indicated isolates were about twice as sensitive to mefenoxam as to metalaxyl. These results provide a systematic understanding of Pythium and Phytopythium species associated with soybean in the Huang‐Huai region, which is important for disease management and breeding programmes.
    Type of Medium: Online Resource
    ISSN: 0032-0862 , 1365-3059
    URL: Issue
    URL: Article
    DOI: 10.1111/ppa.v69.6
    DOI: 10.1111/ppa.13187
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2020845-5
    SSG: 12
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  • 2
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    The overview of antimicrobial peptide‐coated implants against oral bacterial infections
    Wiley ; 2023
    In:  Aggregate Vol. 4, No. 3 ( 2023-06)
    Details
    In: Aggregate, Wiley, Vol. 4, No. 3 ( 2023-06)
    Abstract: Dental implants are the most common therapeutic approach for resolving tooth loss and damage. Despite technical advances in treatment, implant failure rates can be as high as 23% with the major cause of peri‐implantitis: a multi‐species bacterial infection. With an annual growth rate in implant placements of 8.78% per annum, implant failure caused by bacterial infection is a significant oral and general health issue. The rise in antibiotic resistance in oral bacteria further adds pressure to implant failure; thus, there is a need for adjunctive therapy to improve implant outcomes. Due to the broad spectrum of activity and a low risk of inducing bacterial resistance, peptide antibiotics are emerging as a promising implant coating material to reduce/prevent peri‐implantitis and improve dental implant success rates. In this review, we summarised the current strategies of coating antimicrobial peptides (AMPs) onto dental implant material surfaces with multi‐functional properties to enhance osteoblast growth and prevent bacterial infections. This review compared the recent reported literature on dental implant coating with AMPs, which will provide an overview of the current dental implant coating strategies using AMPs and insights for future clinical applications.
    Type of Medium: Online Resource
    ISSN: 2692-4560 , 2692-4560
    URL: Issue
    URL: Article
    DOI: 10.1002/agt2.v4.3
    DOI: 10.1002/agt2.309
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 3045361-6
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  • 3
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    Studies on the interactions between lactam analogs and the N ‐terminal extracellular tail of CC chemokine receptor 4 by CZE
    Wiley ; 2007
    In:  ELECTROPHORESIS Vol. 28, No. 17 ( 2007-09), p. 3064-3069
    Details
    In: ELECTROPHORESIS, Wiley, Vol. 28, No. 17 ( 2007-09), p. 3064-3069
    Abstract: CC chemokine receptor 4 (CCR4) is a kind of G‐protein‐coupled receptors with a characteristic seven‐transmembrane structure and selectively expressed on Th2‐type CD4+ T‐cells, which play a pivotal role in allergic inflammation. In this study, the interactions between 2‐(2‐(2,4‐dichloro‐phenyl)‐4‐{[(2‐methyl‐3‐chloro‐phenyl)‐1‐ylmethyl]‐carbamoyl}‐methyl)‐5‐oxo‐pyrrole‐1‐yl)‐ N ‐(3‐piperidinyl‐propyl)‐acetamide (compound A), a known CCR4 antagonist, and ML40 were studied by CZE for the first time. Both qualitative and quantitative characterizations of the drug–peptide binding were determined. The binding constant of the interaction between the trans ‐diastereomer of compound A and ML40, calculated from the Scatchard plot by regression, was (1.06 ± 0.11)×10 5 /M. Also, it was confirmed that the trans ‐diastereomer was more potent affinity with CCR4 than its cis ‐counterpart. The experimental results show that this reported method by CZE for the determination of the compound A and ML40 interactions is powerful, sensitive, and fast, requires less amounts of reagents, and further, it can be employed as one of the reliable screening methods to a series of lactam analogs in the drug discovery for allergic inflammation diseases.
    Type of Medium: Online Resource
    ISSN: 0173-0835 , 1522-2683
    URL: Issue
    URL: Article
    DOI: 10.1002/elps.v28:17
    DOI: 10.1002/elps.200700258
    Language: English
    Publisher: Wiley
    Publication Date: 2007
    detail.hit.zdb_id: 1475486-1
    SSG: 12
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  • 4
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    Performance‐Enhancing Approaches for PEDOT:PSS‐Si Hybrid Solar Cells
    Wiley ; 2021
    In:  Angewandte Chemie International Edition Vol. 60, No. 10 ( 2021-03), p. 5036-5055
    Details
    In: Angewandte Chemie International Edition, Wiley, Vol. 60, No. 10 ( 2021-03), p. 5036-5055
    Abstract: The emerging energy crisis has focused significant worldwide attention on solar cells. Although crystalline silicon solar cells are currently widely used, their high cost limits the development of solar power generation. Consequently, hybrid solar cells are becoming increasingly important, especially organic‐Si hybrid solar cells (HSCs). Organic‐Si HSCs combine a mature technology and high efficiency with the low‐temperature manufacturing process and tunable optoelectronic properties of organic solar cells. The organic material can be P3HT, carbon nanotubes, graphene, and PEDOT:PSS. Here we review the performance of PEDOT:PSS/Si HSCs and methods for improving their efficiency, such as PEDOT:PSS modification, optimization of the trapping effect, passivation of the silicon surface, addition of an interface layer, improvement of a back contact, and optimization of the metal top electrode. This Review should help fill the gap in this area and provide perspectives for the future development of the PEDOT:PSS/Si HSCs.
    Type of Medium: Online Resource
    ISSN: 1433-7851 , 1521-3773
    URL: Issue
    URL: Article
    DOI: 10.1002/anie.v60.10
    DOI: 10.1002/anie.201910629
    RVK:
    VA 2100
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2011836-3
    detail.hit.zdb_id: 123227-7
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  • 5
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    Super‐Tough and Fast Adhesion of Soft Elastomer Based on Strong Noncovalent Interaction in Diverse Environments
    Wiley ; 2023
    In:  Advanced Functional Materials Vol. 33, No. 50 ( 2023-12)
    Details
    In: Advanced Functional Materials, Wiley, Vol. 33, No. 50 ( 2023-12)
    Abstract: Soft polymer adhesives to achieve high adhesion energy on both dry and wet surfaces in a simple and universal way is a significant challenge. Here, this work introduces an inherently adhesive and transparent elastomer that exhibits in situ adhesion capabilities across a variety of surfaces. These surfaces include, but are not limited to, glass, steel, aluminum, polyethylene terephthalate (PET), and poly(tetrafluoroethylene) (PTFE) sheets, with the remarkable feature of requiring no chemical reaction for adhesion. The elastomer adhesive achieves a super‐high adhesion force above 3000 N m −1 within 10 min, far superior to previously reported intrinsically adhesive polymers. The strong adhesion derives from the increase in hydrogen bonding density between the adhesive elastomer and adherend, high mobility of polymer chains, and matrix hysteresis during interfacial separation. Moreover, the noncovalent interactions can weaken at low temperatures, allowing the intrinsically adhesive elastomer to be easily removed when frozen. The development of intrinsically adhesive and transparent elastomer with super‐high adhesion force on both dry and wet surfaces provides a meaningful way for a wide range of applications.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    URL: Article
    DOI: 10.1002/adfm.v33.50
    DOI: 10.1002/adfm.202304653
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 6
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    Strategien zur Steigerung der Leistung von PEDOT:PSS/Si‐Hybrid‐Solarzellen
    Wiley ; 2021
    In:  Angewandte Chemie Vol. 133, No. 10 ( 2021-03), p. 5092-5112
    Details
    In: Angewandte Chemie, Wiley, Vol. 133, No. 10 ( 2021-03), p. 5092-5112
    Abstract: Vor dem Hintergrund aktueller Energieprobleme haben Solarzellen weltweit eine große Aufmerksamkeit erfahren. Die Entwicklung der Solarstromerzeugung wird von den hohen Kosten herkömmlicher Solarzellen auf der Basis von kristallinem Silicium gebremst. Aus diesem Grund steigt das Interesse an Hybrid‐Solarzellen (HSCs) auf der Basis von organischen Materialien sowie Si. Diese kombinieren die Vorteile einer vorhandenen ausgereiften Technologie und eines hohen Wirkungsgrades mit Vorteilen organischer Solarzellen wie die Herstellung bei niedriger Temperatur und abstimmbare optoelektronische Eigenschaften. Die verwendeten organischen Materialien sind P3HT, Kohlenstoff‐Nanoröhren, Graphen und PEDOT:PSS. Dieser Aufsatz beschäftigt sich mit der Leistung von PEDOT:PSS/Si‐HSCs sowie mit den Methoden zur Steigerung ihres Wirkungsgrades, d. h. mit der PEDOT:PSS‐Modifizierung, der Optimierung des Lichtfalleneffekts, der Passivierung der Si‐Oberfläche, dem Einbau einer Grenzflächenschicht, der Verbesserung des Rückkontakts und mit der Optimierung der metallischen Deckelektrode. Der vorliegende Artikel betrifft einen Themenbereich, der in einschlägigen Publikationen bisher wenig Berücksichtigung fand, und soll Perspektiven für die künftige Entwicklung von PEDOT:PSS/Si‐HSCs aufzeigen.
    Type of Medium: Online Resource
    ISSN: 0044-8249 , 1521-3757
    URL: Issue
    URL: Article
    DOI: 10.1002/ange.v133.10
    DOI: 10.1002/ange.201910629
    RVK:
    VA 2100
    RVK:
    VN 5020
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 505868-5
    detail.hit.zdb_id: 506609-8
    detail.hit.zdb_id: 514305-6
    detail.hit.zdb_id: 505872-7
    detail.hit.zdb_id: 1479266-7
    detail.hit.zdb_id: 505867-3
    detail.hit.zdb_id: 506259-7
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  • 7
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    P4‐293: Oligomeric amyloid‐β peptide on sialyl Lewis X ‐selectin bonding at the cerebral endothelial cell surface
    Wiley ; 2008
    In:  Alzheimer's & Dementia Vol. 4, No. 4S_Part_23 ( 2008-07)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 4, No. 4S_Part_23 ( 2008-07)
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Article
    DOI: 10.1016/j.jalz.2008.05.2362
    Language: English
    Publisher: Wiley
    Publication Date: 2008
    detail.hit.zdb_id: 2201940-6
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  • 8
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    Effects of antimicrobial peptide and tributyrin on fecal microflora and blood indices of female calves
    Wiley ; 2023
    In:  Food Science & Nutrition Vol. 11, No. 9 ( 2023-09), p. 5248-5257
    Details
    In: Food Science & Nutrition, Wiley, Vol. 11, No. 9 ( 2023-09), p. 5248-5257
    Abstract: This study evaluated the effects of antimicrobial peptide (AMP) and tributyrin (TB) on dairy calves in terms of growth performance, immunity, oxidative stress, and intestinal microflora. A total of 40 female calves were divided into four treatment groups ( n  = 10): basal diet +0.015% essential oil, basal diet +0.03% AMP, basal diet +0.15% TB, and basal diet +0.03% AMP + 0.15% TB. AMP and TB supplementation increased the average daily gain (ADG) and weaning weight, while reducing diarrhea occurrence. Additionally, AMP and TB supplementation reduced the levels of reactive oxygen species (ROS) and malonaldehyde (MDA), while increasing superoxide dismutase (SOD) levels and serum immunoglobulin M (IgM) levels. However, the combined use of AMP and TB did not significantly affect the average daily feed intake, ADG, weaning weight, or diarrhea incidence but decreased ROS levels, while increasing SOD levels as well as MDA and IgM levels. Moreover, AMP and TG supplementation increased the relative abundance of several beneficial fiber‐ and mucin‐degrading bacteria in the gut, in contrast to combined AMP and TB supplementation. The 16S rRNA results showed that AMP supplementation significantly increased the relative abundance of Rikenellaceae_RC9_gut_group , Ruminococcaceae_UCG‐014 and [Eubacterium]_coprostanoligenes group ( p   〈  .01), and significantly decreased the relative abundance of Ruminococcaceae_UCG‐005 and Christensenellaceae_R‐7_group ( p   〈  .01). The TB supplementation significantly increased the abundances of Rikenellaceae_RC9_gut_group and Ruminococcaceae_UCG‐005 ( p   〈  .01), and significantly decreased the relative abundances of Ruminococcaceae_UCG‐014 , [Eubacterium]_coprostanoligenes group and Christensenellaceae_R‐7_group ( p   〈  .01). The combined use of AMP and TB significantly increased the relative abundance of Rikenellaceae_RC9_gut_group and Bacteroides ( p   〈  .01), and significantly decreased the relative abundance of Ruminococcaceae_UCG‐014 , [Eubacterium]_coprostanoligenes group and Christensenellaceae_R‐7_group ( p   〈  .01). In summary, diets supplemented with either AMP or TB improved the intestinal microflora, growth performance, and health of weaned calves, but combined use was detrimental to calf performance.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v11.9
    DOI: 10.1002/fsn3.3483
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2703010-6
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  • 9
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    Influence of membrane cholesterol and substrate elasticity on endothelial cell spreading behavior
    Wiley ; 2013
    In:  Journal of Biomedical Materials Research Part A Vol. 101A, No. 7 ( 2013-07), p. 1994-2004
    Details
    In: Journal of Biomedical Materials Research Part A, Wiley, Vol. 101A, No. 7 ( 2013-07), p. 1994-2004
    Abstract: Interactions between implanted materials and the surrounding host cells critically affect the fate of bioengineered materials. In this study, the biomechanical response of bovine aortic endothelial cells (BAECs) with different membrane cholesterol levels to polyacrylamide (PA) gels was investigated by measuring cell adhesion and spreading behaviors at varying PA elasticity. The elasticity of gel substrates was manipulated by cross‐linker content. Type I collagen (COL1) was coated on PA gel to provide a biologically functional environment for cell spreading. Precise quantitative characterization of changes in cell area and perimeter of cells across two treatments and three bioengineered substrates were determined using a customized software developed for computational image analysis. We found that the initial response of endothelial cells to changes in substrate elasticity was determined by membrane cholesterol levels, and that the extent of endothelial cell spreading increases with membrane cholesterol content. All of the BAECs with different cholesterol levels showed little growth on substrates with elasticity below 20 kPa, but increased spreading at higher substrate elasticity. Cholesterol‐depleted cells were consistently smaller than control and cholesterol‐enriched cells regardless of substrate elasticity. These observations indicate that membrane cholesterol plays an important role in cell spreading on soft biomimetic materials constructed with appropriate elasticity. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.
    Type of Medium: Online Resource
    ISSN: 1549-3296 , 1552-4965
    URL: Issue
    URL: Article
    DOI: 10.1002/jbm.a.v101a.7
    DOI: 10.1002/jbm.a.34504
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 1477192-5
    SSG: 12
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  • 10
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    Does the prognosis of colorectal mucinous carcinoma depend upon the primary tumour site? Results from two independent databases
    Wiley ; 2013
    In:  Histopathology Vol. 63, No. 5 ( 2013-11), p. 603-615
    Details
    In: Histopathology, Wiley, Vol. 63, No. 5 ( 2013-11), p. 603-615
    Abstract: Mucinous adenocarcinoma ( MUC ) is a commonly studied histological subtype of colorectal adenocarcinoma. However, the prognostic value of MUC remains unclear, particularly in patients stratified by the primary tumour site. We aimed to analyse the prognostic value of MUC in colorectal cancer. Methods and results We utilized two independent data sets in this study: (i) the N ational C ancer I nstitute's S urveillance, E pidemiology and E nd R esults ( SEER ) data set, and (ii) the data set from a single C hinese institution (the D epartment of S urgical O ncology at the F irst H ospital of C hina M edical U niversity). Patient survival was analysed using K aplan– M eier survival curves, and comparisons were performed using the log‐rank test. MUC occurred more frequently in patients who exhibited higher pT category, higher pN category, higher TNM stage, left‐sided colon cancer and higher histological grade. Based on the SEER data set, MUC was an independent negative survival indicator in rectal cancer (HR 1.125, 1.056–1.199; P  〈   0.001). While there was no significant association in left‐sided colon cancer ( P  〉   1.000), MUC was an independent protective survival indicator in right‐sided colon cancer (HR 0.925, 0.888–0.962; P  〈   0.001). Conclusions MUC was associated independently with poorer outcome for rectal cancer and was an independent protective survival indicator in right‐sided colon cancer. MUC exhibited a different outcome depending on tumour position for patients with colorectal cancer.
    Type of Medium: Online Resource
    ISSN: 0309-0167 , 1365-2559
    URL: Issue
    URL: Article
    DOI: 10.1111/his.2013.63.issue-5
    DOI: 10.1111/his.12190
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2006447-0
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