In:
Molecules, MDPI AG, Vol. 19, No. 4 ( 2014-04-22), p. 5088-5108
Abstract:
Natural dibenzo-α-pyrones are an important group of metabolites derived from fungi, mycobionts, plants and animal feces. They exhibit a variety of biological activities such as toxicity on human and animals, phytotoxicity as well as cytotoxic, antioxidant, antiallergic, antimicrobial, antinematodal, and acetylcholinesterase inhibitory properties. Dibenzo-α-pyrones are biosynthesized via the polyketide pathway in microorganisms or metabolized from plant-derived ellagitannins and ellagic acid by intestinal bacteria. At least 53 dibenzo-α-pyrones have been reported in the past few decades. This mini-review aims to briefly summarize the occurrence, biosynthesis, biotransformation, as well as their biological activities and functions. Some considerations related to synthesis, production and applications of dibenzo-α-pyrones are also discussed.
Type of Medium:
Online Resource
ISSN:
1420-3049
DOI:
10.3390/molecules19045088
Language:
English
Publisher:
MDPI AG
Publication Date:
2014
detail.hit.zdb_id:
2008644-1
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