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  • 1
    Online Resource
    Online Resource
    AIP Publishing ; 2022
    In:  Chinese Journal of Chemical Physics Vol. 35, No. 3 ( 2022-06-01), p. 578-588
    In: Chinese Journal of Chemical Physics, AIP Publishing, Vol. 35, No. 3 ( 2022-06-01), p. 578-588
    Abstract: Herein we present a facile approach for the preparation of a novel hierarchically porous carbon, in which seaweeds serve as carbon source and KOH as activator. The fabricated KOH-activated seaweed carbon (K-SC) displays strong affinity towards tetracycline with maximum uptake quantity of 853.3 mg/g, significantly higher than other tetracycline adsorbents. The superior adsorption capacity ascribes to large specific surface area (2614 m2/g) and hierarchically porous structure of K-SC, along with strong π-π interactions between tetracycline and K-SC. In addition, the as-prepared K-SC exhibits fast adsorption kinetics, capable of removing 99% of tetracycline in 30 min. Meanwhile, the exhausted K-SC can be regenerated for four cycling adsorption without an obvious degradation in capacities. More importantly, pH and ionic strengths barely affect the adsorption performance of K-SC, implying electrostatic interactions hardly play any role in tetracycline adsorption process. Furthermore, the K-SC packed fixed-bed column (0.1 g of adsorbents) can continually treat 2780 mL solution spiked with 5.0 mg/g tetracycline before reaching the breakthrough point. All in all, the fabricated K-SC equips with high adsorption capacity, fast adsorption rate, glorious anti-interference capability and good reusability, which make it hold great feasibilities for treating tetracycline contamination in real applications.
    Type of Medium: Online Resource
    ISSN: 1674-0068 , 2327-2244
    Language: English
    Publisher: AIP Publishing
    Publication Date: 2022
    detail.hit.zdb_id: 2381472-X
    SSG: 6,25
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  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 2020
    In:  Women and Birth Vol. 33, No. 1 ( 2020-02), p. e67-e71
    In: Women and Birth, Elsevier BV, Vol. 33, No. 1 ( 2020-02), p. e67-e71
    Type of Medium: Online Resource
    ISSN: 1871-5192
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 2238614-2
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  • 3
    Online Resource
    Online Resource
    Royal Society of Chemistry (RSC) ; 2021
    In:  Dalton Transactions Vol. 50, No. 7 ( 2021), p. 2648-2653
    In: Dalton Transactions, Royal Society of Chemistry (RSC), Vol. 50, No. 7 ( 2021), p. 2648-2653
    Type of Medium: Online Resource
    ISSN: 1477-9226 , 1477-9234
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2021
    detail.hit.zdb_id: 1472887-4
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  • 4
    In: Tropical Medicine & International Health, Wiley, Vol. 25, No. 2 ( 2020-02), p. 209-215
    Abstract: L'accouchement par césarienne à la demande de la mère est l'un des principaux problèmes de santé publique en Chine. Notre étude visait à appliquer la théorie du comportement planifié afin de déterminer de manière exhaustive les facteurs associés à la préférence des femmes enceintes pour la césarienne, et de fournir des références pour établir des mesures visant à réduire l'accouchement par césarienne à la demande de la mère. Méthodes Cette analyse transversale a été réalisée dans quatre hôpitaux pour femmes et enfants en Chine de mai à juin 2018. Des femmes éligibles arrivant pour des visites prénatales de routine dans ces hôpitaux ont été recrutées pour répondre à un questionnaire structuré. Au total, 1.853 femmes enceintes ont consenti à participer à l'enquête, avec un taux de réponse de 88,75%. AU total, 1.677 femmes enceintes (984 nullipares et 693 multipares) ont été incluses dans l'analyse. Des statistiques descriptives et des analyses de régression logistique ont été utilisées. Résultats Parmi les participantes à l'étude, 20,39% ont préféré une césarienne. Pour les nullipares et les multipares, celles qui avaient des scores d'attitudes plus faibles envers l'accouchement vaginal, des scores plus faibles de l'efficacité propre de l'accouchement et des scores plus élevés des normes subjectives étaient plus susceptibles de préférer la césarienne. Conclusions Les préférences d’accouchement des femmes enceintes étaient significativement associées à leurs attitudes à l'égard du mode d'accouchement, de l'efficacité propre de l'accouchement et des normes subjectives, ce qui est conforme à la théorie du comportement planifié. Des interventions pour réduire l'accouchement par césarienne à la demande de la mère peuvent être développées sur la base de la théorie du comportement planifié.
    Type of Medium: Online Resource
    ISSN: 1360-2276 , 1365-3156
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2018112-7
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  • 5
    In: Frontiers in Neuroscience, Frontiers Media SA, Vol. 16 ( 2022-12-15)
    Abstract: Isorhynchophylline is one of the main active ingredients from Uncaria rhynchophylla , the effects and mechanisms of isorhynchophylline on stress-induced emotional disorders and cognitive impairment remain unclear. Methods Long-term potentiation (LTP) in vivo was used for synaptic plasticity evaluation; chronic unpredictable mild stress (CUMS) model was used to evaluate the effect of isorhynchophylline on stress induced emotional disorders and cognitive impairment; sucrose preference test (SPT), open field test (OFT), and elevated plus maze (EPM) were used to evaluate emotional disorders; morris water maze (MWM) test was used to evaluate cognitive impairment; Western blotting (WB) was used to the expression of proteins; high performance liquid chromatography (HPLC) was used to quantify neurotransmitters; Nissl staining was used to identify pathological changes induced by stress. Results In this study, we found that isorhynchophylline improved corticosterone-induced in vivo LTP impairment significantly, indicating positive effects on stress. Therefore, 28-day CUMS model was adopted to evaluate the anti-stress effects of isorhynchophylline. The results showed that isorhynchophylline improved CUMS-induced weight loss, anxiety- and depression-like behaviors, and spatial memory impairment. Isorhynchophylline reduced CUMS-induced corticosterone elevation. N-methyl-D-aspartic acid (NMDA) receptors play an important role in the process of emotion and memory. Glutamate and the expression of GluN2B increased in the CUMS mice, while D-serine and the expression of serine racemase (SR) decreased significantly, and isorhynchophylline restored these changes to normal level. Conclusion These results indicated that isorhynchophylline ameliorated stress-induced emotional disorders and cognitive impairment, modulating NMDA receptors might be one of the underlying mechanisms.
    Type of Medium: Online Resource
    ISSN: 1662-453X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2411902-7
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  • 6
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2020
    In:  International Health Vol. 12, No. 2 ( 2020-03-12), p. 101-106
    In: International Health, Oxford University Press (OUP), Vol. 12, No. 2 ( 2020-03-12), p. 101-106
    Abstract: Early diagnosis and treatment are essential for effective tuberculosis (TB) control. However, delays in the diagnosis and treatment of TB in central China have not been sufficiently investigated. This cross-sectional study was conducted between October 2013 and March 2014 in Hubei, China to identify risk factors of delays in care seeking, diagnosis and treatment among patients with TB. Methods A total of 1342 patients with TB seen in the designated institutions were included. Multivariate logistic regression was used to analyse factors associated with delays in TB diagnosis and treatment. Results Overall, 21.54%, 23.62% and 42.25% of patients with TB experienced delays in care seeking, diagnosis and treatment, respectively. Multivariate logistic regression showed that medical insurance and monthly household income were significantly associated with delays in care seeking. The time to reach a township hospital or the facility of a patient’s first consultation was significantly associated with delays in diagnosis. Sex, education, time to reach a township hospital and the facility where the diagnosis was made were significantly associated with delays in treatment. Conclusions Delays in TB diagnosis and treatment in Hubei remain a serious issue. Improvements in the capability and accessibility of health care services are imperative to reduce delays and expedite TB diagnosis and treatment.
    Type of Medium: Online Resource
    ISSN: 1876-3413 , 1876-3405
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2020
    detail.hit.zdb_id: 2514131-4
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  • 7
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  BMC Psychiatry Vol. 22, No. 1 ( 2022-12)
    In: BMC Psychiatry, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)
    Abstract: Maternal anxiety induced by neonatal jaundice has adverse effects on maternal and infant health, but there was no specific tool to identify the anxiety level of mothers. This study aims to develop a Maternal Anxiety for Neonatal Jaundice Scale (MANJS) and to validate it in the target population. Methods An initial 11-items MANJS was developed through literature review, expert panel consultation, and a pilot-test. Subsequently, mothers of neonates with jaundice were recruited from the Maternal and Child Health Hospital of Hainan Province, China, from June to December 2018, for a formal questionnaire survey. Based on the data collected, the scale was validated for construct validity, convergent validity, discriminant validity, content validity, and internal consistency reliability after the items screening. Results The reliability and validity of MANJS were validated in 1127 mothers of jaundiced neonates. After the item with cross-loadings was removed using exploratory factor analysis, MANJS consisted of two dimensions and 10 items, with a cumulative variance contribution of 74.36% and factor loadings above 0.6 for all items. The confirmatory factor analysis identified three items with cross-factor loading or error correlation and then they were removed orderly. The further confirmatory factor analysis showed a good construct validity for the 7-item MANJS, with standardized root mean square residual (SRMR) = 0.029, root mean square error of approximation (RMSEA) = 0.068, comparative fit index (CFI) = 0.961, Tucker-Lewis index (TLI) = 0.937, incremental fit index (IFI) = 0.961, normed fit index (NFI) = 0.954, goodness of fit index (GFI) = 0.998, adjusted goodness of fit index (AGFI) = 0.996, respectively. The average variance extracted values (AVE) of the two factors were 0.80 and 0.72, and the combined reliability (CR) were 0.94 and 0.88, respectively. Cronbach’s alpha was 0.90 for the MANJS, and split-half reliability was 0.72. Conclusions MANJS was demonstrated to have satisfactory reliability and validity in evaluating maternal anxiety caused by neonatal jaundice among Chinese postpartum women.
    Type of Medium: Online Resource
    ISSN: 1471-244X
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2050438-X
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  • 8
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2020
    In:  Journal of Public Health Vol. 28, No. 5 ( 2020-10), p. 575-582
    In: Journal of Public Health, Springer Science and Business Media LLC, Vol. 28, No. 5 ( 2020-10), p. 575-582
    Type of Medium: Online Resource
    ISSN: 2198-1833 , 1613-2238
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 1149070-6
    detail.hit.zdb_id: 2140791-5
    detail.hit.zdb_id: 2136860-0
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  • 9
    In: SSRN Electronic Journal, Elsevier BV
    Type of Medium: Online Resource
    ISSN: 1556-5068
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
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  • 10
    In: ORL, S. Karger AG, Vol. 85, No. 3 ( 2023), p. 128-140
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Chronic rhinosinusitis (CRS) is a common inflammatory disease in otolaryngology, mainly manifested as nasal congestion, nasal discharge, facial pain/pressure, and smell disorder. CRS with nasal polyps (CRSwNP), an important phenotype of CRS, has a high recurrence rate even after receiving corticosteroids and/or functional endoscopic sinus surgery. In recent years, clinicians have focused on the application of biological agents in CRSwNP. However, it has not reached a consensus on the timing and selection of biologics for the treatment of CRS so far. 〈 b 〉 〈 i 〉 Summary: 〈 /i 〉 〈 /b 〉 We reviewed the previous studies of biologics in CRS and summarized the indications, contraindications, efficacy assessment, prognosis, and adverse effects of biologics. Also, we evaluated the treatment response and adverse reactions of dupilumab, omalizumab, and mepolizumab in the management of CRS and made recommendations. 〈 b 〉 〈 i 〉 Key Messages: 〈 /i 〉 〈 /b 〉 Dupilumab, omalizumab, and mepolizumab have been approved for the treatment of CRSwNP by the US Food and Drug Administration. Type 2 and eosinophilic inflammation, need for systemic steroids or contraindication to systemic steroids, significantly impaired quality of life, anosmia, and comorbid asthma are required for the use of biologics. Based on current evidence, dupilumab has the prominent advantage in improving quality of life and reducing the risk of comorbid asthma in CRSwNP among the approved monoclonal antibodies. Most patients tolerate biological agents well in general with few major or severe adverse effects. Biologics have provided more options for severe uncontrolled CRSwNP patients or patients who refuse to have surgery. In the future, more novel biologics will be assessed in high-quality clinical trials and applied clinically.
    Type of Medium: Online Resource
    ISSN: 0301-1569 , 1423-0275
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1483533-2
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