In:
Journal of Applied Toxicology, Wiley, Vol. 37, No. 5 ( 2017-05), p. 530-544
Abstract:
Here is presented a comprehensive investigation of the distribution of polyvinylpyrrolidone (PVP)‐stabilized AgNP (20 or 110 nm) in pregnant rats after a single injection or oral gavage dose. The biological impacts of AgNP exposure were evaluated by metabolomic analysis, and measurement of biomarkers of cardiovascular injury, oxidative stress and inflammation. The investigation provided a basic understanding of the distribution, internal dose, persistence, metabolomics and elimination of AgNP after exposure in pregnant rats.
Type of Medium:
Online Resource
ISSN:
0260-437X
,
1099-1263
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
1475015-6
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