In:
Journal of Surgical Oncology, Wiley, Vol. 102, No. 6 ( 2010-11), p. 634-639
Abstract:
Though sentinel lymph node biopsy (SLNB) is an integral component of melanoma staging, little is known about its use in children. Methods Patients (0–18 years) with melanoma diagnosed from 2003 to 2007 in the National Cancer Data Base were assessed. Logistic regression models were used to identify clinicopathologic, socioeconomic, and hospital factors associated with SLNB use and lymph node metastases (LNM). Results Of 671 children, 68.7% underwent SLNB. SLNB utilization rates were 39.9% for T1a patients and 87.6% for T1b–T3 patients. T1b–T3 patients were more likely to undergo SLNB if they were older (OR 4.86 95% CI: 1.88–12.59) or cared for at Children's hospitals (OR 2.43 95% CI: 1.09–5.40). T1b–T3 patients were less likely to undergo SLNB if uninsured (OR 0.25 95% CI: 0.08–0.76). Of those with SLNB, 118 (25.6%) had pathologically confirmed LNM. Patients were more likely to have LNM if younger (OR 3.19 95% CI: 1.20–8.51) or having higher T stage (OR 10.38 95% CI: 4.59–23.47). Conclusions SLNB use for children with melanoma was associated with clinicopathologic, socioeconomic, and hospital factors. Younger patients have a higher likelihood of LNM but are the least likely to undergo SLNB. Though overall adherence appears high, there remains an opportunity for improved care for children with melanoma. J. Surg. Oncol. 2010;102:634–639. © 2010 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
0022-4790
,
1096-9098
Language:
English
Publisher:
Wiley
Publication Date:
2010
detail.hit.zdb_id:
1475314-5
Permalink