In:
International Journal of Cancer, Wiley, Vol. 146, No. 9 ( 2020-05), p. 2628-2635
Kurzfassung:
What's new? Diagnosing endometrial cancer generally relies on histopathological analysis of endometrial biopsy samples. However, these tests are inconclusive in up to 30% of patients. To find a better way, these authors tested whether genetic analysis of endometrial or cervical samples could boost the diagnostic accuracy of the test. They tested 59 EC patients and 31 controls for 8 different genetic mutations using tissue from either Pap brush samples, pipelle biopsies, or self‐samples. Combining histopathology with mutation testing increased sensitivity from 79% to 93‐97%.
Materialart:
Online-Ressource
ISSN:
0020-7136
,
1097-0215
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2020
ZDB Id:
218257-9
ZDB Id:
1474822-8
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