In:
Journal of Medical Imaging and Radiation Oncology, Wiley, Vol. 60, No. 2 ( 2016-04), p. 255-259
Abstract:
We assessed the inter‐ and intra‐observer variability in contouring the prostate bed for radiation therapy planning using MRI compared with computed tomography ( CT ). Methods We selected 15 patients with prior radical prostatectomy. All had CT and MRI simulation for planning purposes. Image fusions were done between CT and MRI . Three radiation oncologists with several years of experience in treating prostate cancer contoured the prostate bed first on CT and then on MRI . Before contouring, each radiation oncologist had to review the R adiation T herapy O ncology G roup guidelines for postoperative external beam radiotherapy. The agreement between volumes was calculated using the D ice similarity coefficient ( DSC ). Analysis was done using the Matlab software. The DSC was compared using non‐parametric statistical tests. Results Contouring on CT alone showed a statistically significant ( P = 0.001) higher similarity between observers with a mean DSC of 0.76 (standard deviation ± 0.05) compared with contouring on MRI with a mean of 0.66 (standard deviation ± 0.05). Mean intra‐observer variability between CT and MRI was 0.68, 0.75 and 0.78 for the three observers. The clinical target volume was 19–74% larger on CT than on MRI . The intra‐observer difference in clinical target volume between CT and MRI was statistically significant in two observers and non‐significant in the third one ( P = 0.09). Conclusions We found less inter‐observer variability when contouring on CT than on MRI . R adiation T herapy O ncology G roup contouring guidelines are based on anatomical landmarks readily visible on CT . These landmarks are more inter‐observer dependent on MRI . Therefore, present contouring guidelines might not be applicable to MRI planning.
Type of Medium:
Online Resource
ISSN:
1754-9477
,
1754-9485
DOI:
10.1111/jmiro.2016.60.issue-2
DOI:
10.1111/1754-9485.12416
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2409071-2
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