In:
Digestive Surgery, S. Karger AG, Vol. 37, No. 4 ( 2020), p. 275-281
Abstract:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 A preoperative scoring system to predict carcinoma in patients with gallbladder polyps (GBPs). 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Preoperative parameters of patients with GBPs who underwent cholecystectomies were used to construct a scoring system to ascertain the risk of malignancy (reference group). The scoring system developed from this approach was applied to the validation group. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 In the reference group, 11.5% of patients had carcinomas, in whom the median age was 68 years and the polyp size was 16.9 mm. According to the univariate analysis, the significant factors for carcinoma were age ≥65 years, the presence of gallstones, polyp size ≥13 mm, solitary polyp, and sessile polyp. Age ≥65 years and polyp size ≥13 mm were significant factors according to the multivariate analysis. From these results, we developed a preoperative scoring system to predict carcinoma. The patients were divided into 1 of 2 groups: low-risk and high-risk and their malignancy rates were 4.1 and 61.1% respectively ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001). In the validation group, the malignancy rate was higher for those in the high-risk group ( 〈 i 〉 p 〈 /i 〉 = 0.016). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 The proposed preoperative scoring system based on simple clinical variables appears to be useful for predicting malignancy in patients with GBPs.
Type of Medium:
Online Resource
ISSN:
0253-4886
,
1421-9883
Language:
English
Publisher:
S. Karger AG
Publication Date:
2020
detail.hit.zdb_id:
1468560-7
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