In:
Frontiers in Psychiatry, Frontiers Media SA, Vol. 12 ( 2021-11-23)
Abstract:
Background: Herein, we validate the psychometric properties of the Chinese version of the THINC-integrated tool (THINC-it) as a screening tool for cognitive deficits in patients with major depressive disorder. The primary aim of this study is to determine whether cognitive deficits as detected by the THINC-it tool in adults with major depressive disorder (MDD) are associated with workplace productivity and/or psychosocial function. Methods: Subjects aged 18–65 ( n = 91) with MDD were evaluated and compared to age-, sex- and education- matched healthy controls ( n = 95). Symptoms of cognitive dysfunction, workplace productivity, and psychosocial function were measured using the THINC-it tool, Hamilton Depression Scale (HAMD), Sheehan Disability Scale (SDS), The Work Productivity and Activity Impairment questionnaire- Specific Health Problem (WPAI-SHP). Results: There were significant differences in THINC-it scores ( p & lt; 0.01), the average of HAMD total score ( p & lt; 0.01) and all aspects of SDS ( p & lt; 0.01) between two groups. There were significant differences in the four aspects of WPAI between the two groups in the employed status ( p & lt;0.01). THINC-it subjective cognition and SDS total score, SDS work/school, SDS social, SDS family showed significantly correlation ( r ranging from 0.255 to 0.386, p & lt;0.01). SDS and THINC-it Objective cognition, THINC-it comprehensive cognition were no correlation between two groups. HAMD total score and SDS total score, SDS social, SDS family showed significantly correlation ( r ranging
Type of Medium:
Online Resource
ISSN:
1664-0640
DOI:
10.3389/fpsyt.2021.763603
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2021
detail.hit.zdb_id:
2564218-2
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