In:
Pediatrics, American Academy of Pediatrics (AAP), Vol. 103, No. 6 ( 1999-06-01), p. 1295-1297
Abstract:
Behçet's syndrome is a chronic relapsing vasculitis characterized by aphthous stomatitis, genital ulcerations, and uveitis. The disease is a multisystem illness, which may involve the skin, joints, gastrointestinal tract, blood vessels, central nervous system, and other organs. Case Study. We report a case of an infant with features of Behçet's syndrome who did not respond to conventional immunosuppression with high-dose corticosteroids and cytotoxic agents. Thalidomide, a potent immune response-modifying drug, was used with marked improvement and resolution of symptoms. Conclusion. This finding supports a trial of thalidomide treatment in patients with Behçet's syndrome who are unresponsive to other forms of immunosuppressive therapy or develop undesirable side effects.
Type of Medium:
Online Resource
ISSN:
1098-4275
,
0031-4005
DOI:
10.1542/peds.103.6.1295
Language:
English
Publisher:
American Academy of Pediatrics (AAP)
Publication Date:
1999
detail.hit.zdb_id:
1477004-0
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