In:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, Korean College of Helicobacter and Upper Gastrointestinal Research, Vol. 22, No. 2 ( 2022-06-10), p. 139-145
Abstract:
Background/Aims: The eradication success rate of 〈 i 〉 Helicobacter pylori 〈 /i 〉 ( 〈 i 〉 H. pylori 〈 /i 〉 ) infection with a first-line standard triple therapy (STT) has been decreasing in Korea. However, treatment outcomes of 〈 i 〉 H. pylori 〈 /i 〉 infection in Yeongdong, Gangwon Province have been scarcely reported. This study aimed to investigate the treatment outcomes of 〈 i 〉 H. pylori 〈 /i 〉 infection in a single tertiary care hospital with regional characteristics.Materials and Methods: From July 2018 to June 2019, a total of 592 patients who underwent STT consisting of a proton pump inhibitor, amoxicillin, and clarithromycin for 7 to 14 days as a first-line 〈 i 〉 H. pylori 〈 /i 〉 eradication therapy were included. Demographic data and treatment outcomes were retrospectively reviewed using medical records.Results: The median age of 592 patients was 58 years (range 23 to 86) and 329 patients (55.6%) were men. The indication for eradication therapy included chronic atrophic gastritis (57.9%), peptic ulcer disease (19.6%), and gastric neoplasm after endoscopic resection (5.9%). Most patients (92.2%) received a 7-day course of STT. Eradication rate of STT was 64.0% (379/592). Rescue therapy was performed in 146 patients, and the final eradication rate reached 85.6% (507/592).Conclusions: Eradication rate of STT in Yeongdong area of Gangwon Province was unsatisfactory, warranting the consideration of a first-line eradication regimen other than STT.
Type of Medium:
Online Resource
ISSN:
1738-3331
,
2671-826X
DOI:
10.7704/kjhugr.2021.0065
Language:
English
Publisher:
Korean College of Helicobacter and Upper Gastrointestinal Research
Publication Date:
2022
detail.hit.zdb_id:
3071420-5
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