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  • 1
    Online Resource
    Online Resource
    Rapid weather changes are associated with increased ischemic stroke risk: a case-crossover study
    Springer Science and Business Media LLC ; 2016
    In:  European Journal of Epidemiology Vol. 31, No. 2 ( 2016-2), p. 137-146
    Details
    In: European Journal of Epidemiology, Springer Science and Business Media LLC, Vol. 31, No. 2 ( 2016-2), p. 137-146
    Type of Medium: Online Resource
    ISSN: 0393-2990 , 1573-7284
    URL: Article
    DOI: 10.1007/s10654-015-0060-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2016
    detail.hit.zdb_id: 2004992-4
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  • 2
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    Online Resource
    Weather, Weather Changes and the Risk of Bell’s Palsy: A Multicenter Case-Crossover Study
    S. Karger AG ; 2018
    In:  Neuroepidemiology Vol. 51, No. 3-4 ( 2018), p. 207-215
    Details
    In: Neuroepidemiology, S. Karger AG, Vol. 51, No. 3-4 ( 2018), p. 207-215
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 To evaluate if weather or changes in weather are risk factors for Bell’s palsy (BP) as exposure to draught of cold air has been popularly associated with the occurrence of BP. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Using a multicenter hospital-based case-crossover study, we analyzed the association between ambient temperature, atmospheric pressure, relative air humidity or their 24 h changes and the risk for BP in 825 patients or subgroups. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 One day following a 24 h increase in atmospheric pressure of more than 6 hPa, the risk for BP increased by 35% (OR 1.35; 95% CI 1.03–1.78) in the overall population. The risk for BP more than doubled in patients with diabetes mellitus after rapid variations in ambient temperature, independent of the direction (temperature decrease & #x3e; 2.25°C; OR 2.15; 95% CI 1.08–4.25; temperature increase between 0.75 and 2.25°C; OR 2.88; 95% CI 1.63–5.10). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Our findings support the hypothesis of an association between certain weather conditions and the risk for BP with acute changes in atmospheric pressure and ambient temperature as the main risk factors. Additionally, contrasting results for risk of BP after temperature changes in the diabetic and non-diabetic subgroups support the paradigm of a diabetic facial palsy as a distinct disease entity.
    Type of Medium: Online Resource
    ISSN: 0251-5350 , 1423-0208
    URL: Article
    DOI: 10.1159/000492671
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2018
    detail.hit.zdb_id: 1483032-2
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  • 3
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    Online Resource
    Weather conditions associated with subarachnoid hemorrhage: a multicenter case-crossover study
    Springer Science and Business Media LLC ; 2021
    In:  BMC Neurology Vol. 21, No. 1 ( 2021-12)
    Details
    In: BMC Neurology, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-12)
    Abstract: Most spontaneous subarachnoid hemorrhages (SAH) occur unexpectedly and independently of classical risk factors. In the light of increasing climate variability and change, we investigated weather and rapid weather changes as possible short-term risk factors for SAH. Methods Seven hundred ninety one patients admitted to three major hospitals in Germany for non-traumatic SAH with a determinable onset of SAH symptoms were included in this hospital-based, case-crossover study. The effects of atmospheric pressure, relative air humidity, and ambient temperature and their 24 h changes on the onset of SAH under temperate climate conditions were estimated. Results There was no association between the risk of SAH and 24 h weather changes, mean daily temperature or mean relative air humidity in the overall population. For every 11.5 hPa higher mean daily atmospheric pressure, the risk of SAH increased by 15% (OR 1.15, 95% confidence interval (CI) 1.01–1.30) in the entire study population with a lag time of three days. Conclusion Our results suggest no relevant association between 24 h-weather changes or absolute values of ambient temperature and relative humidity and the risk of SAH. The medical significance of the statistically weak increase in SAH risk three days after exposure to high atmospheric pressure is unclear. However, as the occurrence of stable high-pressure systems will increase with global warming and potentially affect SAH risk, we call for confirming studies in different geographical regions to verify our observations.
    Type of Medium: Online Resource
    ISSN: 1471-2377
    URL: Article
    DOI: 10.1186/s12883-021-02312-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2041347-6
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  • 4
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    Online Resource
    Rapid increases in nitrogen oxides are associated with acute myocardial infarction: A case-crossover study
    Oxford University Press (OUP) ; 2018
    In:  European Journal of Preventive Cardiology Vol. 25, No. 16 ( 2018-11), p. 1707-1716
    Details
    In: European Journal of Preventive Cardiology, Oxford University Press (OUP), Vol. 25, No. 16 ( 2018-11), p. 1707-1716
    Abstract: High concentrations of air pollutants are associated with increased risk for myocardial infarction. The European Union has defined statutory limits for air pollutants based on upper absolute concentrations. We evaluated the association between rapid changes in air pollutants and the risk of myocardial infarction independently of absolute concentrations. Methods and results Using a hospital-based case-crossover study, effects of 24h changes of nitrogen oxides (NO X/2 ), particulate matter (PM 10 ), and ozone on the risk of myocardial infarction was assessed in 693 patients. In the overall population, increases of NO X of more than 20 µg/m 3 within 24 h were associated with an increase in the risk of myocardial infarction by up to 121% (odds ratio (OR) 2.21, 95% confidence interval (CI) 1.19–4.08). Comparably, rapid increases of NO 2 of more than 8 µg/m 3 tended to increase myocardial infarction risk by 73% (OR 1.73, 95% CI 0.91–3.28) while myocardial infarction risk decreased by 60% after a decrease of NO 2 concentration of more than 8 µg/m 3 (OR 0.4, 95% CI 0.21–0.77), suggesting a close-to-linear association. While results for ozone concentrations were ambiguous, rapid change in PM 10 was not associated with myocardial infarction risk. Conclusion Dynamics and extent of increase in nitrogen oxide concentrations may be an independent risk factor for myocardial infarction. As there are currently no European Union statutory limits reflecting this dynamic variation of air pollutants on a daily basis, the results urgently call for confirming studies in different geographical regions to verify the observations.
    Type of Medium: Online Resource
    ISSN: 2047-4873 , 2047-4881
    URL: Article
    DOI: 10.1177/2047487318755804
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2018
    detail.hit.zdb_id: 2646239-4
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  • 5
    Online Resource
    Online Resource
    Weather as a risk factor for epileptic seizures: A case‐crossover study
    Wiley ; 2017
    In:  Epilepsia Vol. 58, No. 7 ( 2017-07), p. 1287-1295
    Details
    In: Epilepsia, Wiley, Vol. 58, No. 7 ( 2017-07), p. 1287-1295
    Abstract: Most epileptic seizures occur unexpectedly and independently of known risk factors. We aimed to evaluate the clinical significance of patients’ perception that weather is a risk factor for epileptic seizures. Methods Using a hospital‐based, bidirectional case‐crossover study, 604 adult patients admitted to a large university hospital in Central Germany for an unprovoked epileptic seizure between 2003 and 2010 were recruited. The effect of atmospheric pressure, relative air humidity, and ambient temperature on the onset of epileptic seizures under temperate climate conditions was estimated. Results We found a close‐to‐linear negative correlation between atmospheric pressure and seizure risk. For every 10.7 hPa lower atmospheric pressure, seizure risk increased in the entire study population by 14% (odds ratio [OR] 1.14, 95% confidence interval [CI] 1.01–1.28). In patients with less severe epilepsy treated with one antiepileptic medication, seizure risk increased by 36% (1.36, 1.09–1.67). A high relative air humidity of 〉 80% increased seizure risk in the entire study population by up to 48% (OR 1.48, 95% CI 1.11–1.96) 3 days after exposure in a J‐shaped association. High ambient temperatures of 〉 20°C decreased seizure risk by 46% in the overall study population (OR 0.54, 95% CI 0.32–0.90) and in subgroups, with the greatest effects observed in male patients (OR 0.33, 95% CI 0.14–0.74). Significance Low atmospheric pressure and high relative air humidity are associated with an increased risk for epileptic seizures, whereas high ambient temperatures seem to decrease seizure risk. Weather‐dependent seizure risk may be accentuated in patients with less severe epilepsy. Our results require further replication across different climate regions and cohorts before reliable clinical recommendations can be made.
    Type of Medium: Online Resource
    ISSN: 0013-9580 , 1528-1167
    URL: Issue
    URL: Article
    DOI: 10.1111/epi.2017.58.issue-7
    DOI: 10.1111/epi.13776
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2002194-X
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