In:
Angewandte Chemie, Wiley, Vol. 129, No. 28 ( 2017-07-03), p. 8201-8205
Abstract:
Herein, we report on the first sila‐aldol reaction, which emphasizes the tight connection between silicon and carbon chemistry. This novel synthetic method provides straightforward access to 2‐oxahexasilabicyclo[3.2.1]octan‐8‐ide, a structurally complex silicon framework, in quantitative yield. Its structure was confirmed by NMR spectroscopy and X‐ray crystallography, and it displays a distinctive charge‐transfer transition. The complete mechanism of this highly selective rearrangement cascade is outlined and supported by density functional theory (DFT) calculations, which highlight the thermodynamic driving force and the low activation barriers of this powerful silicon–carbon bond‐forming strategy.
Type of Medium:
Online Resource
ISSN:
0044-8249
,
1521-3757
DOI:
10.1002/ange.v129.28
DOI:
10.1002/ange.201701862
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
505868-5
detail.hit.zdb_id:
506609-8
detail.hit.zdb_id:
514305-6
detail.hit.zdb_id:
505872-7
detail.hit.zdb_id:
1479266-7
detail.hit.zdb_id:
505867-3
detail.hit.zdb_id:
506259-7
Permalink