In:
Urologia Internationalis, S. Karger AG, Vol. 105, No. 5-6 ( 2021), p. 507-513
Abstract:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 The diffusion-weighted imaging (DWI) technique with intravoxel incoherent motion model enables the estimation of capillary blood volume as a perfusion-related parameter- (PP-) value. Therefore, the PP-value of the kidney theoretically reflects renal capillary blood volume. We analyzed the usefulness of the PP-value in estimating postoperative renal function in upper-tract urothelial carcinoma (UTUC) patients. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Forty-eight consecutive patients who underwent magnetic resonance imaging before radical nephroureterectomy from 2011 to 2018 were analyzed. A PP-map displaying PP-values on a pixel-by-pixel basis was created from DWI signals ( 〈 i 〉 b 〈 /i 〉 -values of 0, 500, and 1,000 s/mm 〈 sup 〉 2 〈 /sup 〉 ). Two readers independently analyzed the renal PP-value. DWI-based split renal function (SRF) of the intact kidney was calculated by splitting serum Cr-based preoperative estimated glomerular filtration rates (eGFRs). The predictive accuracy of the method was evaluated using renography as the reference standard. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Interobserver analysis revealed an excellent correlation value of 0.97. The SRF value showed a good linear correlation with the observed postoperative eGFR ( 〈 i 〉 r 〈 /i 〉 = 0.76, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001). The predictive accuracy of the DWI-based method was similar to that of the nuclear-based method. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 This DWI-based evaluation of capillary blood volume provides a noninvasive tool for predicting the postoperative renal function, thereby facilitating the management of UTUC patients.
Type of Medium:
Online Resource
ISSN:
0042-1138
,
1423-0399
Language:
English
Publisher:
S. Karger AG
Publication Date:
2021
detail.hit.zdb_id:
1464417-4
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