In:
Journal of Clinical Microbiology, American Society for Microbiology, Vol. 24, No. 2 ( 1986-08), p. 304-306
Abstract:
Because the immunoglobulin G (IgG) response to carbohydrate antigens is typically from the IgG2 subclass and the IgG response to protein antigens is typically from the IgG1 and sometimes the IgG3 subclass, two respiratory syncytial virus glycoproteins, F and G, which differ substantially in the amount of glycosylation, were used as antigens in an enzyme-linked immunosorbent assay to determine IgG subclass responses in 20 infants and young children with naturally acquired respiratory syncytial virus infection. Both glycoproteins elicited primarily IgG1 and IgG3 responses, indicating that the protein moieties of the glycoproteins may be immunodominant in this age group.
Type of Medium:
Online Resource
ISSN:
0095-1137
,
1098-660X
DOI:
10.1128/jcm.24.2.304-306.1986
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1986
detail.hit.zdb_id:
1498353-9
SSG:
12
Permalink