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  • 1
    Online Resource
    Online Resource
    Influences of Thyroid Hormones on the Alteration of Autonomic Nervous System in Female Patients with Overt Hyperthyroidism
    Revista de Chimie SRL ; 2019
    In:  Revista de Chimie Vol. 70, No. 7 ( 2019-8-15), p. 2552-2555
    Details
    In: Revista de Chimie, Revista de Chimie SRL, Vol. 70, No. 7 ( 2019-8-15), p. 2552-2555
    Abstract: The aim of this study is to document the impact of thyroid hormones on the autonomic nervous system (ANS), expressed by heart rate variability (HRV) and heart rate turbulence (HRT), in patients with hyperthyroidism, compared to controls. Another purpose is to determine if HRV and HRT parameters are significantly correlated with the levels of thyroid hormones and the duration of hyperthyroidism. We studied HRV, in time and frequency domain, and HRT in a group of 113 premenopausal women, with still untreated overt hyperthyroidism, without cardiovascular diseases or risk factors for atherosclerosis, admitted between 2015 and 2018 in the Endocrinology Clinic of our hospital and compared the results with data obtained in 29 healthy controls. Depending on the severity and duration of hyperthyroidism and levels of thyroid hormones, patients were assigned to three groups: mild and moderate hyperthyroidism, severe and recurrent forms. We performed 24 hours Holter monitoring in patients and controls. Regarding HRV parameters in time domain, they were significantly depressed in patients comparing to controls. Referring to HRT, all patients had abnormal, positive values of turbulence onset (TO) and we documented statistically significant differences (p[0.001) when compared to controls. All patients had normal positive values of turbulence slope (TS), which decreased parallel with the severity of hyperthyroidism. In patients with hyperthyroidism, we documented depressed values of HRV parameters in time domain, correlated with the duration and severity of the thyroid disease. Our patients had pathologic values of TO. Although positive, TS values were lower when compared to controls.
    Type of Medium: Online Resource
    ISSN: 0034-7752 , 2668-8212
    URL: Article
    DOI: 10.37358/RC.19.7.7378
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2019
    detail.hit.zdb_id: 2488208-2
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  • 2
    Online Resource
    Online Resource
    Increased Susceptibility for Thromboembolic Events versus High Bleeding Risk Associated with COVID-19
    MDPI AG ; 2022
    In:  Microorganisms Vol. 10, No. 9 ( 2022-08-29), p. 1738-
    Details
    In: Microorganisms, MDPI AG, Vol. 10, No. 9 ( 2022-08-29), p. 1738-
    Abstract: The infection with the SARS-CoV-2 virus is associated with numerous systemic involvements. Besides the severe respiratory injuries and cardiovascular complications, it became obvious early on that this disease carries an increased risk of thromboembolic events, but a higher propensity for bleedings as well. We researched the medical literature over significant PubMed published articles debating on the prevalence, category of patients, the moment of occurrence, and evolution of venous thromboembolism (VTE), but also of venous and arterial “in situ” thrombosis (AT), and hemorrhagic events as well. Most researchers agree on an increased prevalence of thromboembolic events, ranging between 25 and 31% for VTE, depending on the analyzed population. For AT and hemorrhagic complications lower rates were reported, namely, about 2–3%, respectively, between 4.8 and 8%, occurring mostly in older patients, suffering from moderate/severe forms of COVID-19, with associated comorbidities. It is important to mention that patients suffering from hemorrhages frequently received thromboprophylaxis with anticoagulant drugs. As a consequence of thromboembolic and hemorrhagic complications which are both important negative prognostic factors, the evolution of patients infected with the SARS-CoV-2 virus is aggravated, determining an augmented morbidity and mortality of this population.
    Type of Medium: Online Resource
    ISSN: 2076-2607
    URL: Article
    DOI: 10.3390/microorganisms10091738
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2720891-6
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  • 3
    Online Resource
    Online Resource
    Dacron Reconstruction of Aortic Aneurysm and Long Term Patients Evolution
    Revista de Chimie SRL ; 2019
    In:  Materiale Plastice Vol. 56, No. 2 ( 2019-6-30), p. 405-408
    Details
    In: Materiale Plastice, Revista de Chimie SRL, Vol. 56, No. 2 ( 2019-6-30), p. 405-408
    Abstract: Aortic aneurysm (AA) and especially dissecting aneurism (DAA) represent life threatening medical conditions and vascular reconstruction surgery with the insertion of a vascular prosthetic grafts is often required to save patients life. In this paper we debate over the long term outcome of 23 patients who underwent five to eight years ago an aortic reconstruction surgery with insertion of Dacron grafts. They attended, during 2018, the emergency room of the County Emergency Hospital Pius Brinzeu of Timisoara in terms of patency complications of the prosthesis. Despite slight dilatation of the Dacron graft and of the native aorta, presence of mural thrombi and/or progress of aortic regurgitation, their evolution was satisfactory, without severe complications.
    Type of Medium: Online Resource
    ISSN: 0025-5289 , 2668-8220
    URL: Article
    DOI: 10.37358/MP.19.2.5195
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2019
    detail.hit.zdb_id: 2487166-7
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  • 4
    Online Resource
    Online Resource
    Study Upon the Serum Level of Uric Acid and the Metabolic Syndrome Components
    Revista de Chimie SRL ; 2019
    In:  Revista de Chimie Vol. 70, No. 3 ( 2019-4-15), p. 1062-1066
    Details
    In: Revista de Chimie, Revista de Chimie SRL, Vol. 70, No. 3 ( 2019-4-15), p. 1062-1066
    Abstract: The serum level of uric acid (UA) appears to be associated with a variety of cardiometabolic risk factors; however, direct association with the metabolic syndrome (MetS) remains controversial. The aim of this study is to investigate the association between serum levels of UA and the components that define MetS, differentiated by gender. 262 patients were enrolled (132 women and 130 men); mean value of the age: 58.7�16 year. Hyperuricemia was considered when the level of serum UA �7mg/dL in men, and � 6mg/dL in women; MetS was defined according to the IDF criteria. The prevalence of MetS in the studied group was 35.11% and the prevalence of hyperuricemia was 16.79%. Men with hyperuricemia had the highest prevalence of abdominal obesity (87.5% vs. 66.32%, p [0.001) and hypertriglyceridemia (65.62% vs. 45.91%, p [ 0.001) versus men with normal level of serum UA. Women with hyperuricemia also had a significantly higher incidence of abdominal obesity (75% vs. 57.51%, p [0.001), hypertriglyceridemia (58.33% vs. 38.33%, p [0.001), decreased HDL (50% vs. 33.33%, p [0.001) and hyperglycemia (66.66% versus 50%, p [0.001) compared to those with normal levels of serum UA. The majority of men with hyperuricemia have more than 4 of the MetS components. Hyperuricemia had a higher prevalence in patients with MetS, it may be considered as a causal factor of MetS. Elevated levels of serum uric acid were significantly more associated with the increasing number of MetS components. Early detection and treatment of hyperuricemia is essential for preventing the metabolic syndrome and its complications.
    Type of Medium: Online Resource
    ISSN: 0034-7752 , 2668-8212
    URL: Article
    DOI: 10.37358/RC.19.3.7064
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2019
    detail.hit.zdb_id: 2488208-2
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