In:
Journal of Heterocyclic Chemistry, Wiley, Vol. 57, No. 9 ( 2020-09), p. 3271-3278
Abstract:
A new three‐component domino reaction for the synthesis of 2‐amino‐6‐aryl‐5‐(phenylamino)‐3,7‐dihydro‐4 H ‐pyrrolo[2,3‐ d ]pyrimidin‐4‐one derivatives 4 using acetic acid as catalyst has been established. The reaction was performed in aqueous media using readily available and inexpensive 2,6‐diaminopyrimidin‐4(3 H )‐one 1 , 2,2‐dihydroxy‐1‐arylethan‐1‐one 2 and aniline 3 as substrates. The simple and efficient one‐pot three‐component approach, inexpensive catalyst, green reaction media, make the present methodology a good synthetic procedure.
Type of Medium:
Online Resource
ISSN:
0022-152X
,
1943-5193
Language:
English
Publisher:
Wiley
Publication Date:
2020
detail.hit.zdb_id:
2042274-X
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