In:
Journal of Magnetic Resonance Imaging, Wiley, Vol. 33, No. 6 ( 2011-06), p. 1341-1350
Abstract:
To evaluate the MR agreement of cardiac function parameters between volumetric (cine SSFP) and phase contrast flow (PC‐flow) assessment in patients with repaired tetralogy of Fallot (r‐TOF) and chronic pulmonary regurgitation (PR) at rest and under dobutamine stress (DS‐MR). Materials and Methods: We studied 18 patients with r‐TOF and severe chronic PR (34 ± 12.7 years, PR fraction [flow] 44 ± 15%) by cardiac MR at rest, 10 and 20 μg/kg/min of dobutamine. We compared analogous functional parameters by volumetry and PC‐flow: (i) Systemic output [left ventricle stroke volume (LV SV ) versus aortic forward flow (AO FF )], (ii) Pulmonary output [right ventricle stroke volume (RV SV ) versus pulmonary forward flow (PA FF )], (iii) PR volume [(RV SV ‐LV SV ) versus pulmonary backward flow (PA BF )], (iv) PR fraction [(RV SV ‐LV SV /RV SV ) versus (PA BF /PA FF )]. Results: We found excellent Bland‐Altman agreement (mean difference ± limits of agreement, mL/beat/m 2 ) at rest for both the systemic (−0.8 ± 5.7) and pulmonary strokes volumes (−0.1 ± 7.6), which slightly deteriorates during DS‐MR. The PR volume showed acceptable agreement at rest (−3.6 ± 15.1), but also further deteriorated during stress (5.4 ± 24). In contrast, the PR fraction showed poor agreement equally at rest (−5.6 ± 22.8) and DS‐MR (3.2 ± 19.2). Conclusion: In r‐TOF with chronic PR, analogous functional parameters should not be used interchangeably between volumetric and PC‐flow assessment during DS‐MR evaluation. J. Magn. Reson. Imaging 2011;33:1341–1350. © 2011 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
1053-1807
,
1522-2586
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1497154-9
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