In:
Advanced Synthesis & Catalysis, Wiley, Vol. 362, No. 18 ( 2020-09-21), p. 3841-3845
Abstract:
A concise and practical method for the metal‐free synthesis of 1,8‐naphthyridones is described using a two‐step approach involving regioselective amination of pyridine N ‐oxides and acid‐mediated cyclization. This is the first synthesis of 1,8‐naphthyridones utilizing easily accessible pyridine N ‐oxides as substrates. Compared to previous reports, this method benefits from simple operation, easy access to starting materials, and a wide substrate scope, providing a variety of novel 1,8‐naphthyridones. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.v362.18
DOI:
10.1002/adsc.202000769
Language:
English
Publisher:
Wiley
Publication Date:
2020
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
Permalink