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  • PETRAKIS, NICHOLAS L.  (2)
  • 1955-1959  (2)
  • Medicine  (2)
Material
Publisher
Person/Organisation
Language
Years
  • 1955-1959  (2)
Year
Subjects(RVK)
  • Medicine  (2)
RVK
  • 1
    Online Resource
    Online Resource
    The Dead Leukocyte Content of the Blood in Normal and Leukemic Patients
    American Society of Hematology ; 1957
    In:  Blood Vol. 12, No. 4 ( 1957-04-01), p. 367-372
    Details
    In: Blood, American Society of Hematology, Vol. 12, No. 4 ( 1957-04-01), p. 367-372
    Abstract: The dead leukocyte content of the blood of normal and leukemic subjects was determined by the technic of the unstained-cell counts of Schrek. A small and constant number of dead leukocytes was found in the normal blood, averaging 46 per cu. mm. In patients with chronic lymphocytic leukemia and acute leukemia, higher numbers of dead leukocytes were commonly found, ranging from normal values to as high as 4,600 per cu. mm. No correlation was found between the numbers of smudge forms on blood smears from these patients and the number of dead leukocytes. The smudge forms on blood smears appear to result from the mechanical trauma produced in making the smears. The leukocytes from chronic lymphocytic leukemia and acute leukemia appear to be much more susceptible to the mechanical forces produced in the preparation of blood smears than are leukocytes from normals and patients with chronic granulocytic leukemia.
    Type of Medium: Online Resource
    ISSN: 0006-4971 , 1528-0020
    URL: Article
    DOI: 10.1182/blood.V12.4.367.367
    RVK:
    XA 33000
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Hematology
    Publication Date: 1957
    detail.hit.zdb_id: 1468538-3
    detail.hit.zdb_id: 80069-7
    Location Call Number Limitation Availability
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    Online Resource
  • 2
    Online Resource
    Online Resource
    The Cytophotometric Estimation of the Desoxyribonucleic Acid (DNA) Content of Individual Plasma Cells from Multiple Myeloma and Nonspecific Plasmacytoses
    American Society of Hematology ; 1955
    In:  Blood Vol. 10, No. 12 ( 1955-12-01), p. 1204-1213
    Details
    In: Blood, American Society of Hematology, Vol. 10, No. 12 ( 1955-12-01), p. 1204-1213
    Abstract: The cytophotometric technic employing the Feulgen reagent was used to determine the relative amount of DNA in the nuclei of individual myeloma and plasma cells aspirated from the bone marrow. Individual myeloma cells were found to contain markedly elevated amounts of DNA as compared to that in the plasma cells of non-specific plasmacytoses. Myeloma cells were found to contain geometric multiples (2, 4, 8) of the amount of DNA present in normal lymphocytes, and the degree of DNA "ploidy" was related to the morphologic stage of immaturity. Polyploid DNA values were not found in the non-specific plasmacytoses. The possible mechanisms of formation were discussed. The findings are interpreted as suggesting the presence of a basic alteration in the quantitative DNA-chromosome relationship in myeloma cells, and they offer additional support for the separation of the myeloma plasmacytoses from nonspecific plasmacytoses.
    Type of Medium: Online Resource
    ISSN: 0006-4971 , 1528-0020
    URL: Article
    DOI: 10.1182/blood.V10.12.1204.1204
    RVK:
    XA 33000
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Hematology
    Publication Date: 1955
    detail.hit.zdb_id: 1468538-3
    detail.hit.zdb_id: 80069-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
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