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  • SAGE Publications  (4)
  • 1
    Online Resource
    Online Resource
    An integrated online adaptive state of charge estimation approach of high-power lithium-ion battery packs
    SAGE Publications ; 2018
    In:  Transactions of the Institute of Measurement and Control Vol. 40, No. 6 ( 2018-04), p. 1892-1910
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 40, No. 6 ( 2018-04), p. 1892-1910
    Abstract: A novel online adaptive state of charge (SOC) estimation method is proposed, aiming to characterize the capacity state of all the connected cells in lithium-ion battery (LIB) packs. This method is realized using the extended Kalman filter (EKF) combined with Ampere-hour (Ah) integration and open circuit voltage (OCV) methods, in which the time-scale implementation is designed to reduce the computational cost and accommodate uncertain or time-varying parameters. The working principle of power LIBs and their basic characteristics are analysed by using the combined equivalent circuit model (ECM), which takes the discharging current rates and temperature as the core impacts, to realize the estimation. The original estimation value is initialized by using the Ah integral method, and then corrected by measuring the cell voltage to obtain the optimal estimation effect. Experiments under dynamic current conditions are performed to verify the accuracy and the real-time performance of this proposed method, the analysed result of which indicates that its good performance is in line with the estimation accuracy and real-time requirement of high-power LIB packs. The proposed multi-model SOC estimation method may be used in the real-time monitoring of the high-power LIB pack dynamic applications for working state measurement and control.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/0142331217694681
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Tacrolimus in the treatment of myasthenia gravis in patients with an inadequate response to glucocorticoid therapy: randomized, double-blind, placebo-controlled study conducted in China
    SAGE Publications ; 2017
    In:  Therapeutic Advances in Neurological Disorders Vol. 10, No. 9 ( 2017-09), p. 315-325
    Details
    In: Therapeutic Advances in Neurological Disorders, SAGE Publications, Vol. 10, No. 9 ( 2017-09), p. 315-325
    Abstract: To determine the efficacy of low-dose, immediate-release tacrolimus in patients with myasthenia gravis (MG) with inadequate response to glucocorticoid therapy in a randomized, double-blind, placebo-controlled study. Methods Eligible patients had inadequate response to glucocorticoids (GCs) after ⩾6 weeks of treatment with prednisone ⩾0.75 mg/kg/day or 60–100 mg/day. Patients were randomized to receive 3 mg tacrolimus or placebo daily (orally) for 24 weeks. Concomitant glucocorticoids and pyridostigmine were allowed. Patients continued GC therapy from weeks 1–4; from week 5, the dose was decreased at the discretion of the investigator. The primary efficacy outcome measure was a reduction, relative to baseline, in quantitative myasthenia gravis (QMG) score assessed using a generalized linear model; supportive analyses used alternative models. Results Of 138 patients screened, 83 [tacrolimus ( n = 45); placebo ( n = 38)] were enrolled and treated. The change in adjusted mean QMG score from baseline to week 24 was −4.9 for tacrolimus and −3.3 for placebo (least squares mean difference: –1.7, 95% confidence interval: −3.5, −0.1; p = 0.067). A post-hoc analysis demonstrated a statistically significant difference for QMG score reduction of ⩾4 points in the tacrolimus group (68.2%) versus the placebo group (44.7%; p = 0.044). Adverse event profiles were similar between treatment groups. Conclusions Tacrolimus 3 mg treatment for patients with MG and inadequate response to GCs did not demonstrate a statistically significant improvement in the primary endpoint versus placebo over 24 weeks; however, a post-hoc analysis demonstrated a statistically significant difference for QMG score reduction of ⩾4 points in the tacrolimus group versus the placebo group. This study was limited by the low number of patients, the absence of testing for acetylcholine receptor antibody and the absence of stratification by disease duration (which led to a disparity between the two groups). ClinicalTrials.gov identifier: NCT01325571
    Type of Medium: Online Resource
    ISSN: 1756-2864 , 1756-2864
    URL: Article
    DOI: 10.1177/1756285617721092
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2442245-9
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Fixed-time second-order sliding mode control for uncertain nonlinear systems subject to non-vanishing mismatched terms
    SAGE Publications ; 2024
    In:  Transactions of the Institute of Measurement and Control
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications
    Abstract: The traditional second-order sliding mode (SOSM) algorithms can only achieve the finite-time regulation for standard integrator sliding mode systems and the convergence time of which is dependent on the system’s initial values and grows as the initial values grow. In this paper, we propose a novel fixed-time SOSM controller whose settling time is bounded by a fixed time independent of the system’s initial values. First, a new sliding mode system subjects to a non-vanishing mismatched term is developed to reduce the input uncertainties and relax the well-defined relative degree assumption. Second, a Lyapunov criterion for practical fixed-time stability with a less conservative convergence time estimation is introduced, based on which a practical fixed-time SOSM controller is designed for the new sliding mode system. Finally, a strict Lyapunov analysis demonstrates that the closed-loop system is globally practically fixed-time stable (GPFxTS). Particularly, if the mismatched term is vanishing, global fixed-time convergence of the sliding variable to zero can be achieved. Buck converter is given as an application.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/01423312241237692
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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    Online Resource
  • 4
    Online Resource
    Online Resource
    Calcium channel blockers and Parkinson’s disease: a systematic review and meta-analysis
    SAGE Publications ; 2024
    In:  Therapeutic Advances in Neurological Disorders Vol. 17 ( 2024-01)
    Details
    In: Therapeutic Advances in Neurological Disorders, SAGE Publications, Vol. 17 ( 2024-01)
    Abstract: The calcium channel has been considered to have great potential as a drug target for neuroprotective therapy in Parkinson’s disease (PD), but previous studies yielded inconsistent results. Objectives: This study aimed to conduct a systematic review and meta-analysis to assess the relationship between using calcium channel blockers (CCBs) and the risk and progression of PD. Data sources and methods: The terms such as ‘Parkinson’s disease’, ‘PD’, ‘calcium channel blockers’, and ‘CCB’ were used to search the literature published before 1 May 2023 in English databases, including PubMed, Embase, and Cochrane Library, for studies on CCB and PD. Data analysis was performed using Review Manager 5.3 software. Results: A total of 190 works of literature were preliminarily retrieved, and 177 works of literature were excluded by eliminating duplicates, reading abstracts, and reading full texts. A total of nine studies were finally included in the meta-analysis of the CCB and the risk of PD, and five studies were included in the systematic review of the CCB and the progression of PD. A total of 2,961,695 participants were included in the meta-analysis. The random-effects model was used for analysis due to significant heterogeneity. The main results of the meta-analysis showed that the use of CCB could reduce the risk of PD (relative risk 0.78, 95% confidence interval 0.62–0.99). Conclusion: CCB use was associated with a significantly reduced risk of PD. Whether CCB use has a disease-modifying effect on PD needs further study. Registration: PROSPERO: CRD42024508242.
    Type of Medium: Online Resource
    ISSN: 1756-2864 , 1756-2864
    URL: Article
    DOI: 10.1177/17562864241252713
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2442245-9
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    Online Resource
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