In:
Digestive Surgery, S. Karger AG, Vol. 21, No. 3 ( 2004), p. 242-245
Abstract:
〈 i 〉 Background: 〈 /i 〉 The standard surgical procedure for intraductal papillary-mucinous neoplasm of the pancreatic head is pylorus-preserving pancreatoduodenectomy. A less extensive resection may be justified because most intraductal papillary-mucinous neoplasms are benign or of low-grade malignancy. 〈 i 〉 Aims and Methods: 〈 /i 〉 The outcome of duodenum-preserving pancreatic head resection with preservation of the main bile duct was evaluated retrospectively in 13 patients with a branch-type intraductal papillary-mucinous neoplasm in the head of the pancreas and with a median (range) follow-up of 60.0 (0.3–99.5) months. 〈 i 〉 Results: 〈 /i 〉 Post-operative complications included anastomotic leakage (n = 3), bile duct perforation (n = 1), intra-abdominal bleeding (n = 3), delayed gastric emptying (n = 2) and death (n = 2). All the resection margins were clear of tumour on histological examination. Ten of 11 patients maintained over 90% of their pre-operative body weight. Glucose tolerance improved in 4 of 11 evaluable patients, was unchanged in 6 and worsened in 1 patient. Biliary scintigraphy showed that bile flow was delayed compared with that before surgery (8.8 ± 1.1 vs. 19.6 ± 4.6 min; p = 0.03). Neither recurrence nor metastasis was observed. 〈 i 〉 Conclusion: 〈 /i 〉 The results of duodenum-preserving pancreatic head resection for branch duct-type intraductal papillary-mucinous neoplasm were satisfactory and provided a good quality of life.
Type of Medium:
Online Resource
ISSN:
0253-4886
,
1421-9883
Language:
English
Publisher:
S. Karger AG
Publication Date:
2004
detail.hit.zdb_id:
1468560-7
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