In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 132, No. suppl_3 ( 2015-11-10)
Kurzfassung:
Background: Stent thrombosis (ST) in the coronary artery has been associated with a high mortality rate (45%). Despite its broad use, incidence of ST and its impact on clinical outcome following endovascular therapy (EVT) for femoropopliteal (FP) lesions have not been systematically studied. Methods: Five hundred and fifty-nine consecutive patients (74±9 years; 33% female; 47% with critical limb ischemia; 31% TASC C/D) who underwent stent implantation (81% bare metal and 19% drug-eluting stents) in FP lesions (length, 157±100 mm) were retrospectively studied. ST was diagnosed when the following criteria were met: 1) initial procedural success; 2) rapid symptom occurrence; 3) thrombus present at procedure; and 4) lesion resolved with 〈 50% diameter narrowing by thrombolysis. We evaluated the incidence of ST and its impact on major adverse limb event (MALE)-free survival by Kaplan-Meier analysis and by Cox proportional hazard model. Results: Rate of ST linearly increased during the follow-up and reached 1.6% (7/559) at 36 months following stent implantation. MALE-free survival rate was 74.6% at 36 months after stent implantation. The independent predictors were age (HR), body mass index (HR), CLI (HR), hemodialysis (HR), and chronic heart failure (HR), while ST (0.99; [0.14-7.33] was not significantly associated with MALE-free survival. Conclusion: ST, which occurred in 1.6% at 36 months after stent implantation, was not an independent predictor of MALE-free survival in patients with PAD in FP lesions.
Materialart:
Online-Ressource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.132.suppl_3.14072
Sprache:
Englisch
Verlag:
Ovid Technologies (Wolters Kluwer Health)
Publikationsdatum:
2015
ZDB Id:
1466401-X
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