In:
Chemical Papers, Springer Science and Business Media LLC, Vol. 67, No. 6 ( 2013-01-1)
Abstract:
Tandospirone (I), developed as an anxiolytic drug, is an aryl-piperazine compound that binds to both 5-HT1A and dopamine D4 receptors. Palladium-catalysed hydroarylation reactions of tandospirone analogues containing an oxygen bridge and 3-(trifluoromethyl)phenyl or 2,3-dichlorophenyl groups were studied in order to find a new stereoselective access to a series of new exo-aryl(hetaryl)-substituted derivatives with potential biological activity.
Type of Medium:
Online Resource
ISSN:
1336-9075
DOI:
10.2478/s11696-013-0338-4
Language:
Unknown
Publisher:
Springer Science and Business Media LLC
Publication Date:
2013
detail.hit.zdb_id:
2252770-9
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