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  • 1
    Online Resource
    Online Resource
    Phytochemical content and antioxidant activity of Komba-komba (Eupatorium odoratum L)
    Rynnye Lyan Resources ; 2022
    In:  Food Research Vol. 6, No. 3 ( 2022-6-16), p. 335-341
    Details
    In: Food Research, Rynnye Lyan Resources, Vol. 6, No. 3 ( 2022-6-16), p. 335-341
    Abstract: Komba-komba (Eupatorium odoratum L) is a shrub, which is native to America. Traditionally, komba-komba is used to treat burns, wounds, skin infections, postpartum wounds, malaria, coughs and colds, and has anti-gonorrhoea, anti-inflammatory, anthelmintic, analgesic and antioxidant properties. This study aimed to investigate the phytochemicals from Komba-komba roots and in vitro antioxidant activity. Komba-komba root powder was macerated using methanol as solvent. Then fractionated with n-hexane, chloroform, and ethyl acetate. The antioxidant power was measured using the DPPH radical inhibition method and reducing agents using the FRAP method. Komba-komba root exhibited the strongest antioxidant activity. The ethyl acetate fraction showed the strongest antioxidant activity using both the DPPH method and the FRAP method with IC50 values, 10.0598±0.0665 g/mL, and 16.4782±0.3558 g/mL, respectively. The antioxidant activity of komba-komba root was correlated with its phenolic and flavonoid content. Komba-komba root showed very high phenolic and flavonoid contents to be developed as a source of natural antioxidants.
    Type of Medium: Online Resource
    ISSN: 2550-2166 , 2550-2166
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.26656/fr.2017.6(3)
    DOI: 10.26656/fr.2017
    DOI: 10.26656/fr.2017.6(3).495
    Language: English
    Publisher: Rynnye Lyan Resources
    Publication Date: 2022
    detail.hit.zdb_id: 2925282-9
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  • 2
    Online Resource
    Online Resource
    Pengaruh Pemberian Fraksi Daun Jati terhadap Profil Kadar Glikogen Hati dan Otot Tikus Putih DM Tipe II
    Lembaga Penelitian dan Pengabdian Masyarakat Universitas Mandala Waluya ; 2023
    In:  Jurnal Pharmacia Mandala Waluya Vol. 2, No. 1 ( 2023-02-28), p. 56-62
    Details
    In: Jurnal Pharmacia Mandala Waluya, Lembaga Penelitian dan Pengabdian Masyarakat Universitas Mandala Waluya, Vol. 2, No. 1 ( 2023-02-28), p. 56-62
    Abstract: Diabetes Melitus (DM) adalah penyakit yang disebabkan oleh ketidakseimbangan asupan insulin sehingga menyebabkan glukosa tidak dapat diubah menjadi glikogen. Tectona grandis Linn F. atau daun jati secara empiris digunakan oleh masyarakat untuk pengobatan dan diketahui memiliki aktivitas sebagai antidiabetes. Penelitian ini bertujuan untuk mengetahui profil kada glikogen dalam hati dan otot tikus putih jantan model DM tipe II setelah pemberian fraksi n-heksan, kloroform, dan etil asetat daun jati. Penelitian dilakukan dnegan menggunakan Post Test Only with control group design dan pengujian kadar menggunakan metode spektrofotomteri. Hasil penelitian menunjukkan kadar glikogen hati hewan uji pada kelompok kontrol normal (Kn), kontrol positif (K+), kontrol negatif (K-), kelompok fraksi n-heksana (K1), fraksi kloroform (K2), dan fraksi etil asetat (K3) dengan dosis masing-masing 300 mg/kgBB berturut-turut yaitu 41,24; 46,14; 34,67; 43,00; 46,85; dan 52,70 µg/100mg sampel hati serta kadar glikogen otot masing-masing kelompok berturut-turut yaitu 24,82; 26,62; 19,51; 13,88; 15,43; dan 20,05 µg/100mg sampel otot. Berdasarkan hasil penelitian dapat disimpulkan bahwa fraksi terbaik yang dapat meningkatkan kadar glikogen hati dan otot hewan uji yaitu fraksi etil asetat dengan dosis 300 mg/kgBB.
    Type of Medium: Online Resource
    ISSN: 2829-6850
    URL: Article
    DOI: 10.54883/28296850.v2i1.252
    Language: Unknown
    Publisher: Lembaga Penelitian dan Pengabdian Masyarakat Universitas Mandala Waluya
    Publication Date: 2023
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  • 3
    Online Resource
    Online Resource
    Determination of total phenolic and flavonoid content of Ghontoghe (Kleinhovia hospita L.) leaves: in vitro antioxidant study
    Rynnye Lyan Resources ; 2022
    In:  Food Research Vol. 6, No. 6 ( 2022-12-27), p. 267-272
    Details
    In: Food Research, Rynnye Lyan Resources, Vol. 6, No. 6 ( 2022-12-27), p. 267-272
    Abstract: The Ghontohge plant (Kleinhovia hospita L.) has been used as a traditional medicine to treat scurvy, lice, eye pain, jaundice and hepatitis, cholesterol, diabetes, hypertension and treat pneumonia. Therefore, it is possible that plants can be used as antioxidants and redox signalling sourced from natural materials. The purpose of this study was to investigate the antioxidant potential and evaluate the total phenolic and flavonoid content of Ghontoghe leaves and investigate the most potent fraction as an antioxidant from the extract and fractions of Ghontoghe leaves. Ghontoghe leaf powder was extracted using the maceration method. Antioxidant activity was evaluated using 2,2-diphenyl-1-picryhidrazyl (DPPH) and 2,2-Azinobis 3-ethyl benzothiazoline 6-sulfonic acid radicals (ABTS). The total phenolic content was determined using the Folin-Ciocalteau method. Meanwhile, the total flavonoid content was determined using the aluminium chloride complex colourimetric method. The ethyl acetate fraction showed the strongest antioxidant activity on both DPPH radicals and ABTS radicals with IC50 values of 6.253±0.008 g/mL and 6.486±0.023 g/mL, respectively. The ethyl acetate fraction also showed high phenolic and flavonoid content with values of 26.92±0.10 mg GAE/g sample and 95±0.69 mg QE/g sample, respectively. The ethyl acetate fraction has the potential to be used as a source of natural antioxidants and has the potential to be used as a functional food.
    Type of Medium: Online Resource
    ISSN: 2550-2166 , 2550-2166
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.26656/fr.2017.6(6)
    DOI: 10.26656/fr.2017
    DOI: 10.26656/fr.2017.6(6).440
    Language: English
    Publisher: Rynnye Lyan Resources
    Publication Date: 2022
    detail.hit.zdb_id: 2925282-9
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  • 4
    Online Resource
    Online Resource
    Pendampingan Mitigasi dan Adaptasi Perilaku Baru di Masa Pandemi Covid-19 Melalui Gerakan Masyarakat Menggunakan Masker (GEMAS), Penggunaan Antiseptik dan Desinfektan di Kabupaten Bombana, Sulawesi Tenggar
    STIE Mahardika ; 2020
    In:  Engagement: Jurnal Pengabdian Kepada Masyarakat Vol. 4, No. 2 ( 2020-11-30)
    Details
    In: Engagement: Jurnal Pengabdian Kepada Masyarakat, STIE Mahardika, Vol. 4, No. 2 ( 2020-11-30)
    Abstract: COVID-19 causes worldwide panic and become a global health problem so that it is declared as pandemic since December 2019. Indonesia is a country with 4th population density in the world. The level of spread of COVID-19 patients in Indonesia may be more than countries with smaller populations. South East Sulawesi has confirmed 484 of COVID-19 cases. One of the highest areas with the number of patients is Bombana Regency. The purpose of community service carried out by lecturers and students from Halu Oleo University was to strengthen the role of the people of Bombana Regency in mitigating and adapting to the COVID-19 pandemic. Activities in community service included education and socialization of GEMAS, antiseptics, and disinfectants which were carried out offline (door to door) and online. As well as the distribution of masks and spray hand sanitizer for free. Through this activity, it can be expected to increase public knowledge and awareness in using masks, antiseptics, and disinfectants properly to face COVID-19 pandemic.
    Type of Medium: Online Resource
    ISSN: 2579-8391 , 2579-8375
    URL: Issue
    URL: Article
    DOI: 10.29062/engagement.v4i2
    DOI: 10.29062/engagement.v4i2.354
    Language: Unknown
    Publisher: STIE Mahardika
    Publication Date: 2020
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  • 5
    Online Resource
    Online Resource
    In vitro antioxidant activity of Cocoa (Theobroma cacao L) peel
    Rynnye Lyan Resources ; 2022
    In:  Food Research Vol. 6, No. 4 ( 2022-8-5), p. 287-294
    Details
    In: Food Research, Rynnye Lyan Resources, Vol. 6, No. 4 ( 2022-8-5), p. 287-294
    Abstract: Free radicals are electron-deficient species that are very reactive to cause various diseases, such as diabetes, cholesterol, cardiovascular disease, cancer, hypertension, and others. For this reason, antioxidant compounds are needed that can inhibit the performance of free radicals. Caco is a plant that contains many phenolic and flavonoid compounds that have potential as antioxidants. This study aimed to evaluate the total phenolic and flavonoid content as well as in vitro antioxidant assay. Cocoa fruit powder was macerated with methanol, and then fractionated with n-hexane, chloroform, and ethyl acetate as solvents. The antioxidant power was measured by DPPH and ABTS methods. The phenolic content was determined by the Folin-Ciocalteau method, and the flavonoid content was measured using the AlCl3 colourimetric method. The ethyl acetate fraction showed the strongest antioxidant activity using both the DPPH and ABTS methods with IC50 values of 5.61±0.032 mg/mL and 5.773±0.018 mg/mL, respectively. The total phenolic and flavonoid content of the ethyl acetate fraction showed high values, namely 22.767±0.1097 mg GAE/g sample and 90.337±0.552 mg QE/g sample, respectively. The cocoa peel can be developed as a natural antioxidant and can be used as a functional food.
    Type of Medium: Online Resource
    ISSN: 2550-2166 , 2550-2166
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.26656/fr.2017.6(4)
    DOI: 10.26656/fr.2017
    DOI: 10.26656/fr.2017.6(4).477
    Language: English
    Publisher: Rynnye Lyan Resources
    Publication Date: 2022
    detail.hit.zdb_id: 2925282-9
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  • 6
    Online Resource
    Online Resource
    Development of probiotic drink yogurt from Dillenia serrata thunb: antioxidant and antibacterial potencies
    Rynnye Lyan Resources ; 2022
    In:  Food Research Vol. 6, No. 5 ( 2022-9-16), p. 124-129
    Details
    In: Food Research, Rynnye Lyan Resources, Vol. 6, No. 5 ( 2022-9-16), p. 124-129
    Abstract: Yogurt is a functional drink that has been known to have health benefits. Yogurt has higher antioxidant activity than whole milk. This study aimed to determine the ability of antioxidant and antibacterial activity of Songi fruit extract yogurt. The antioxidant activity was assayed using DPPH (1,1-diphenyl-picrylhydrazyl) and the antibacterial activity using the agar diffusion method with the well-technique against Gram-negative bacteria Escherichia coli ATCC 35218. The test results of secondary metabolites of Songi fruit extract contain tannins, saponins, and flavonoids. The Songi fruit extract was formulated into 4 formulas, which were Formula I (0%), Formula II (10%), Formula III (15%), and Formula IV (20%). The results of the antioxidant activity test obtained with IC50 values of formulas were 121, 75.38, 50.50, and 36.58 mg/mL respectively, and 84.82 mg/mL for commercial yogurt. Test results of antibacterial activity against bacteria E. coli ATCC 35218 with inhibition zone diameters were 0, 0, 1.5, and 3.5 mm, respectively for Formula I-IV, and the commercial yogurt was 0 mm. Formula IV (20% fruit extract yogurt) possessed the highest antioxidant and antibacterial activity with IC50 36.58 mg/mL and an inhibition zone diameter of 3.5 mm. In conclusion, the Songi fruit extract yogurt has antioxidant and antibacterial activity against E. coli.
    Type of Medium: Online Resource
    ISSN: 2550-2166 , 2550-2166
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.26656/fr.2017.6(5)
    DOI: 10.26656/fr.2017
    DOI: 10.26656/fr.2017.6(5).559
    Language: English
    Publisher: Rynnye Lyan Resources
    Publication Date: 2022
    detail.hit.zdb_id: 2925282-9
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    Online Resource
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