In:
Bulletin of the Veterinary Institute in Pulawy, Walter de Gruyter GmbH, Vol. 59, No. 1 ( 2015-03-01), p. 143-148
Abstract:
The effect of inflammatory bowel disease (IBD) on the density of galanin - immunoreactive (GAL-IR) nerve fibers was determined in the mucosa of canine duodenum, jejunum, and descending colon. Fiber density was evaluated by a single immunofluorescence method in biopsy specimens obtained from healthy dogs and patients with variable severity of the disease. The density of GAL-IR nerve fibers was determined by the semi-quantitative method by counting fibers in the field of view (0.l mm 2 ). Fiber density was higher in dogs with moderate and severe IBD than in healthy animals. The results of the study suggest that GAL present in intestinal nerve fibers could play a role in the pathogenesis and development of canine IBD.
Type of Medium:
Online Resource
ISSN:
2300-3235
DOI:
10.1515/bvip-2015-0021
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2015
detail.hit.zdb_id:
2855010-9
detail.hit.zdb_id:
2238950-7
SSG:
22
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