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  • 1
    In: Journal of Clinical Laboratory Analysis, Wiley, Vol. 31, No. 6 ( 2017-11)
    Abstract: Remarkable disagreement among different systems of 25‐hydroxy vitamin D 25( OH )D assay makes decision making for both clinical and community interventions very difficult. This study aimed to harmonize the results obtained from different 25( OH )D assay systems. Methods A total of 275 serum samples were analyzed for 25( OH )D using DIA source‐enzyme immunoassay ( EIA ), DIA source‐radioimmunoassay ( RIA ), Roche‐electrochemiluminescence ( ECL ), Diasorin‐chemiluminescent immunoassay ( CLIA ), and high‐performance liquid chromatography ( HPLC ), as the reference method. Serum intact parathyroid hormone ( iPTH ) was also measured in all samples. Between‐system agreement and harmonization were evaluated using Bland–Altman analysis, receiver operating characteristic ( ROC ), and regression analysis. Results Mean serum 25( OH )D concentrations and frequency distribution of vitamin D status showed a significant difference among the studied systems ( P 〈 .001 for both). Serum 25( OH )D assay results from all systems correlated with those from HPLC . As compared with HPLC , ECL showed a positive bias (+3.8 nmol/L), whereas CLIA had a negative bias (−11.9 nmol/L). Both EIA and RIA showed a more or less similar positive bias (8.0 and 8.1 nmol/L, respectively). Using serum iPTH ‐based 25( OH )D cutoff points, only ECL results became comparable to and without significant difference with HPLC . However, when system‐specific cutoffs were defined based on HPLC results using regression equations, mean 25( OH )D and frequency distribution of vitamin D status were more harmonized compared with the other methods. Conclusion Our findings showed that with adjustment of circulating 25( OH )D based on HPLC , frequency distribution of vitamin D status, as judged by different methods, can be well harmonized with no statistically significant inter‐system difference.
    Type of Medium: Online Resource
    ISSN: 0887-8013 , 1098-2825
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2001635-9
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  • 2
    In: Public Health Nutrition, Cambridge University Press (CUP), Vol. 15, No. 2 ( 2012-02), p. 324-330
    Abstract: To assess the vitamin D status of 9–12-year-old primary-school children in Tehran during autumn and winter 2007–2008. Design A descriptive cross-sectional study. Setting Primary schools of Tehran city, Iran. Subjects A total of 1111 children aged 9–12 years (573 boys and 538 girls) from sixty primary schools were enrolled in the study. Weight, height, BMI and serum levels of Ca, P, Mg, 25-hydroxyvitamin D (25(OH)D), intact parathyroid hormone (iPTH), osteocalcin and bone-specific alkaline phosphatase of all the participants were assessed. Dietary Ca intake was also evaluated using a quantitative FFQ for a subsample of the study population ( n 503). Vitamin D sufficiency was defined on the basis of serum levels of 25(OH)D as either ≥37 nmol/l (criterion 1) or ≥50 nmol/l (criterion 2). Results Daily intake of Ca did not differ significantly between boys and girls (929·6 ( sd 436·7) mg and 909·5 ( sd 465·5) mg, respectively). However, on the basis of the first criterion, approximately 86 % of the children had vitamin D deficiency, with 38·3 % being severely deficient (25(OH)D 〈 12·5 nmol/l). According to the second criterion, prevalence of vitamin D deficiency rose to 91·7 %. Prevalence of vitamin D deficiency was higher in girls than in boys by either criterion. Serum levels of 25(OH)D inversely correlated with iPTH ( r = −0·154, P 〈 0·001) and BMI ( r = −0·092, P = 0·002) but directly correlated with duration of sun exposure ( r = 0·115, P 〈 0·001). Conclusions The high prevalence of vitamin D deficiency among schoolchildren (especially among girls) warrants immediate interventions for proper nutritional support.
    Type of Medium: Online Resource
    ISSN: 1368-9800 , 1475-2727
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2012
    detail.hit.zdb_id: 2016337-X
    SSG: 21
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  • 3
    Online Resource
    Online Resource
    Wiley ; 2016
    In:  Diabetes/Metabolism Research and Reviews Vol. 32, No. 3 ( 2016-03), p. 260-267
    In: Diabetes/Metabolism Research and Reviews, Wiley, Vol. 32, No. 3 ( 2016-03), p. 260-267
    Abstract: Oxidative stress refers to an imbalance between potentially harmful free radicals and the body's mechanisms to efficiently detoxify them in favor of the free radicals. Consequently, excess free radicals can attack and damage a wide range of biomolecules including proteins, lipids and nucleic acids. Antioxidant mechanisms of the body are under the influence of genetic and environmental (including dietary) factors. Diabetes is one of the most common metabolic disorders around the world. A huge body of evidence indicates a role for oxidative stress in development of many human diseases including diabetes. In this article, the latest information on the possible links of oxidative stress with diabetes development, control and complications as well as the newest results of antioxidant supplementation trials is reviewed. In addition, the possible role of vitamin D, as a newly recognized antioxidant in diabetes is discussed. Finally, concluding remarks on pivotal issues and future studies are presented. Copyright © 2015 John Wiley & Sons, Ltd.
    Type of Medium: Online Resource
    ISSN: 1520-7552 , 1520-7560
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2001565-3
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  • 4
    Online Resource
    Online Resource
    Elsevier BV ; 2018
    In:  Nutrition Vol. 47 ( 2018-03), p. 69-74
    In: Nutrition, Elsevier BV, Vol. 47 ( 2018-03), p. 69-74
    Type of Medium: Online Resource
    ISSN: 0899-9007
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2018
    detail.hit.zdb_id: 2010168-5
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  • 5
    In: BMC Research Notes, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2020-12)
    Abstract: An amendment to this paper has been published and can be accessed via the original article.
    Type of Medium: Online Resource
    ISSN: 1756-0500
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2413336-X
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  • 6
    In: BMC Nutrition, Springer Science and Business Media LLC, Vol. 8, No. 1 ( 2022-10-23)
    Abstract: Nutritional inadequacy, especially micronutrients, is still a serious concern among children in developing countries. Dietary diversity score (DDS) has been recommended as a proxy for nutritional adequacy. The present study aims to develop a questionnaire to assess the dietary diversity among 24–59 months children in Iran; also, the validity of the dietary diversity score as an indicator of nutritional status among the children will be assessed. Methods In order to design the questionnaire, the Food and Agriculture Organization Guideline for measuring individual dietary diversity will be applied. According to the guideline, foods are categorized into nine groups, then dietary diversity score will be calculated by summing the number of food groups. In order to evaluate the efficacy of this questionnaire in predicting the nutritional status of the children, the relationship between dietary diversity score calculated by the questionnaire with nutritional adequacy, serum retinol and anthropometric indicators will be compared. Discussion DDS can be a valuable indicator for predicting the adequacy of macronutrients and micronutrients specially in children. It is also significantly related to the mean probability of adequacy (MPA).
    Type of Medium: Online Resource
    ISSN: 2055-0928
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2809847-X
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  • 7
    Online Resource
    Online Resource
    Hogrefe Publishing Group ; 2015
    In:  International Journal for Vitamin and Nutrition Research Vol. 85, No. 1-2 ( 2015-12), p. 61-69
    In: International Journal for Vitamin and Nutrition Research, Hogrefe Publishing Group, Vol. 85, No. 1-2 ( 2015-12), p. 61-69
    Abstract: Abstract. Introduction: There is sparse evidence of the effect of vitamin D on bone biomarkers in diabetic patients, and therefore, in a randomized clinical trial, we evaluated the effects of the daily intake of vitamin D, either with or without extra calcium, on selected bone biomarkers. Materials and Methods: Ninety women and men aged 30 - 50 years old with type 2 diabetes were randomly divided into three groups in a double-blind manner. Group 1 (PD), the control group, received a plain yogurt drink. Groups 2 (DD) and 3 (CDD) received 1000 IU vitamin D3, and 1000 IU vitamin D3 plus 500 mg calcium, respectively, via drinking two 250 mL bottles a day of a fortified yogurt drink for twelve weeks. Anthropometric and biochemical assessments were made, including 25(OH), intact parathyroid hormone (iPTH), osteocalcin, and calcium. Results: Although the time and time×group interaction effects on the bone biomarkers were not statistically significant, there was a modest decrease in iPTH concentrations in both DD and CDD groups over twelve weeks. The subgroups with initial vitamin D deficiency/insufficiency in the CDD group had greater and significant decrease in serum iPTH concentrations after twelve weeks of treatment compared to the PD group (- 9.0 ± 21.2 v.s 8.6 ± 21.8 pg/mL, p = 0.042). Conclusion: The improvement in vitamin D status following the daily intake of fortified doogh for twelve weeks was accompanied by a decrement in iPTH, mostly in those subjects with poor initial vitamin D status.
    Type of Medium: Online Resource
    ISSN: 0300-9831 , 1664-2821
    Language: English
    Publisher: Hogrefe Publishing Group
    Publication Date: 2015
    SSG: 15,3
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  • 8
    In: Journal of Health, Population and Nutrition, Springer Science and Business Media LLC, Vol. 41, No. 1 ( 2022-12)
    Abstract: The COVID-19 epidemic has affected diverse issues of life including economy, health and nutrition. This nationwide study was conducted to evaluate the effects of the epidemic lockdown-induced socio-economic changes on animal source proteins and cereals intakes of Iran population for the first time. Methods This was a cross-sectional descriptive-analytical study using a web-based electronic self-administered questionnaire. A questionnaire was designed with the aim of detecting any changes in the dietary pattern of the Iranian household following coronavirus epidemic. Results A total of 21,290 households participated in the study. Approximately 33%, 24%, 14.2% and 7% of the households had decreased the weekly consumption of red meat, white meat, eggs and rice/bread, respectively, following COVID-19 epidemic. The results of ordered logistic regression showed that the female-headed households, as compared with male-headed ones, were 30% more likely to decrease their weekly consumption of white meat (OR = 1.3, 95% CI: 1.1–1.5). About 8.6% of the households had reduced all three major dietary sources of animal protein. Close to half of the households (46.9%) who decreased their intake of the animal protein sources had increased their intake of rice or bread, too. The major reasons for these changes were decrease of income and job loss. Conclusion In conclusion, animal protein food consumption decreased during epidemic lockdown but the amounts of rice and bread, as the major sources of dietary energy, have increased. These changes, if persist long enough, can seriously affect micronutrient status of the whole population. Early nutritional interventions for needy families are warranted.
    Type of Medium: Online Resource
    ISSN: 2072-1315
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2059676-5
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  • 9
    In: Nutrition & Diabetes, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2021-07-30)
    Abstract: Some evidence suggests indirect ameliorating effects of vitamin D in diabetes via adiponectin and sirtuins. This study aimed to evaluate the effects of daily intake of vitamin D-fortified yogurt drink, either with or without added calcium, on serum adiponectin, sirtuins (SIRT)1 and 6. Methods Briefly, 75 adults aged 30–60 years from both sexes with type 2 diabetes were randomly allocated to one of the three groups: (i) D-fortified-yogurt drink (DY; containing 1000 IU vitamin D and 300 mg calcium), (ii) Ca+D-fortified-yogurt drink (CDY; containing 1000 IU vitamin D and 500 mg calcium) and (iii) plain yogurt drink (PY; containing no detectable vitamin D and 300 mg calcium). All assessments were performed initially and after 12 weeks. Results A significant within-group increment in serum adiponectin concentrations was observed in both DY and CDY groups (+60.4 ± 8.6, +57.5 ± 6.4 µg/L, respectively; p   〈  0.001 for both). The concentrations of SIRT1 and SIRT6 had a significant within-group increment only in the CDY group ( p  = 0.003, p  = 0.001 respectively). Being in CDY group was more favorable predictor of improvement in SIRT6 concentrations. Changes of 25(OH)D were a significant predictor of changes of adiponectin. However, this association disappeared following adjustment for changes of SIRT1. In contrast, the association between changes of 25(OH)D and HbA1c remained significant even after adjustment for SIRT1. Conclusions Daily consumption of vitamin D-fortified yogurt drink for 12 weeks resulted in an increase in circulating concentrations of SIRT1 and SIRT6 in T2D subjects and D+Ca-fortified yogurt drink was more in favor of SIRT6 increment.
    Type of Medium: Online Resource
    ISSN: 2044-4052
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2609314-5
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  • 10
    In: International Dairy Journal, Elsevier BV, Vol. 94 ( 2019-07), p. 53-64
    Type of Medium: Online Resource
    ISSN: 0958-6946
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 1484447-3
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