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  • 1
    Online Resource
    Online Resource
    The Role of Serial NT-ProBNP Level in Prognosis and Follow-Up Treatment of Acute Heart Failure after Coronary Artery Bypass Graft Surgery
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4411-4415
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4411-4415
    Abstract: BACKGROUND: After coronary artery bypass graft (CABG) surgery, heart failure is still major problem. The valuable marker for it is needed. AIM: Evaluating the role of serial NT-proBNP level in prognosis and follow-up treatment of acute heart failure after CABG surgery. METHODS: The prospective, analytic study evaluated 107 patients undergoing CABG surgery at Ho Chi Minh Heart Institute from October 2012 to June 2014. Collecting data was done at pre- and post-operative days with measuring NT-proBNP levels on the day before operation, 2 hours after surgery, every next 24 h until the 5th day, and in case of acute heart failure occurred after surgery. RESULTS: On the first postoperative day (POD1), the NT-proBNP level demonstrated significant value for AHF with the cut-off point = 817.8 pg/mL and AUC = 0.806. On the second and third postoperative day, the AUC value of NT- was 0.753 and 0.751. It was statistically significant in acute heart failure group almost at POD 1 and POD 2 when analyzed by the doses of dobutamine, noradrenaline, and adrenaline (both low doses and normal doses). CONCLUSION: Serial measurement of NT-proBNP level provides useful prognostic and follow-up treatment information in acute heart failure after CABG surgery.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.872
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    Clinical and Microbiological Features of Pediatric Endopthalmitis After Open Globe Injury in the North of VietNam
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4306-4310
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4306-4310
    Abstract: BACKGROUND: Pediatric endophthalmitis after open-globe injury had its clinical features, microbiological profile different from those in aldults. In Viet Nam, there was no report on the clinical and microbiological characteristic of pediatric posttraumatic endophthalmitis. Therefore, we conduct this study. AIM: To describe clinical features, ultrasound results, gram stain and culture results of endophthalmitis in pediatric open globe injuries. METHODS: Prospective non-controlled study. Case series of 30 eyes presenting with post-traumatic endophthalmitis between 2015 and 2016 were reviewed. RESULTS: Mean age was 8.03 ± 3.99 years. Metallic and organic etiologies were most common causes for injuries (n = 11). 27 cases had penetrating corneal trauma. Dense opaque vitreous was seen in 25 eyes. Retinal necrosis 〈 1 quadrant and chorioretinal abscess 〉 1 quadrant were most common fundus lesions. Dense vitreous opacity on ultrasound was most common (n = 28). Gram stain bacteria positivity was 93.3%, gram-positive were isolated in 63.3%. Vitreous samples were more often positive than aqueous (P = 0,002). CONCLUSION: Posttraumatic endophthalmitis in children is more common in boys aged 6-10 years and most often caused by injury with metallic and organic matter. Culture results were very low. Vitreous samples were more often positive than aqueous. Gram-positive bacteria were the most common causative organism.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.380
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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  • 3
    Online Resource
    Online Resource
    Evaluation of Anterior Chamber Depth and Anterior Chamber Angle Changing After Phacoemulsification in the Primary Angle Close Suspect Eyes
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4297-4300
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4297-4300
    Abstract: BACKGROUND: Phacoemulsification surgery has the ability to deeply alter the segment anterior morphology, especially in eye with shallow anterior chamber (AC), narrow anterior chamber angle (ACA). However, the changes of anterior chamber depth (ACD) and ACA on the close angle suspect eyes after phacoemulsification have not been mentioned in many studies. So, we conduct this research. AIM: To evaluate the alteration in the ACA and ACD after phacoemulsification in the close angle suspect eyes. METHODS: Interventional study with no control group. Subjects were the primary angle closure suspect (PACS) eyes, that were operated by phacoemulsification with intraocular lens (IOL) at Glaucoma Department of VNIO from December 2017 to October 2018. RESULTS: 29 PACS eyes with cataract were operated by phacoemulsification with intraocular lens. After 3 months of monitoring, the average ACD augmented from 2.082 ± 0.244 to 3.673 ± 0.222 mm. AOD500 increase from 0.183 ± 0.088 to 0.388 ± 0.132 μm, AOD750 increased from 0.278 ± 0.105 to 0.576 ± 0.149 μm. The TISA500 enlarged from 0.068 ± 0.033 to 0.140 ± 0.052 mm2, TISA750 enlarged from 0.125 ± 0.052 to 0.256 ± 0.089 mm2 at the third month (p 〈 0.01). CONCLUSION: Phacoemulsification surgery increases the ACD and enlarged the angle in the PACS eyes.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.378
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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  • 4
    Online Resource
    Online Resource
    Short Tandem Repeats Used in Preimplantation Genetic Testing of Β-Thalassemia: Genetic Polymorphisms For 15 Linked Loci in the Vietnamese Population
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4383-4388
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4383-4388
    Abstract: BACKGROUND: β-thalassemia is one of the most common monogenic diseases worldwide. Preimplantation genetic testing (PGT) of β-thalassemia is performed to avoid affected pregnancies has become increasingly popular worldwide. In which, the indirect analysis using short tandem repeat (STRs) linking with HBB gene to detect different β-globin (HBB) gene mutation is a simple, accurate, economical and also provides additional control of contamination and allele-drop-out ADO. AIM: This study established microsatellite markers for PGT of Vietnamese β-thalassemia patient. METHODS: Fifteen (15) STRs gathered from 5 populations were identified by in silico tools within 1 Mb flanking the HBB gene. The multiplex PCR reaction was optimized and performed on 106 DNA samples from at-risk families. RESULTS: After estimating, PIC values were ≥ 0.7 for all markers, with expected heterozygosity and observed heterozygosity values ranged from 0.81 to 0.92 and 0.53 to 0.86, respectively. One hundred percent of individuals had at least seven heterozygous markers and were found to be heterozygous for at least two markers on either side of the HBB gene. The STRs panel was successfully performed on one at-risk family. CONCLUSION: In general, a pentadecaplex marker (all 〈 1 Mb from the HBB gene) assay was constituted for β-thalassemia PGT on Vietnamese population.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.840
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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  • 5
    Online Resource
    Online Resource
    Assessing the Status of Filtering Blebs at 5 Year Post- Trabeculectomy
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4278-4282
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4278-4282
    Abstract: BACKGROUND: Glaucoma is a common cause of blindness in the world as well as in Vietnam. It is treated by many different methods but trabeculectomy is still the most popular and highly effective surgical method to treat this condition. AIM: To analyze the status of 5 years filtering blebs following trabeculectomy and to explore multiple factors associated with filtering blebs. METHODS: This is a retrospective, cross-sectional descriptive study. Eyes had been performed trabeculectomy for 5 years were included in these results. The filtering blebs were assessed using slit lamp and OCT. the OCT captured bleb area to evaluate fluid subconjunctival spaces, thickness and height of bleb and to evaluate the related factors RESULTS: A group of 106 primary glaucoma eyes of 97 patients (88 patients with 1 eye, 9 patients 2 eyes) had been performed trabeculectomy for 5 years were taken OCT anterior image. The proportion of female patients is 1.5 times that of male patients. IOP was controlled with or without topical medication in all eyes. The filtering bleb had a high echo reflection, which accounted for 42.5%, the average echo reflection was 38.6%, the low echo reflection response of 18.9%. 66% of the eyes had the aqueous space under the conjunctiva, 65.1% have the aqueous space under sclera flap, the average height of the bleb on OCT was 0.4 mm ± 0.3 mm. Young patients often have a higher rate of bleb fibrosis and loss of function than older patients CONCLUSION: OCT is capable of assessing the function of bleb. After 5 years of trabeculectomy, on the OCT image, most cases of blebs are maintaining drainage function.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.374
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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  • 6
    Online Resource
    Online Resource
    Dry Eyes Status on Des Scale and Related Factors in Outpatients at Vietnam National Institute of Ophthalmology
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4292-4296
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4292-4296
    Abstract: BACKGROUND: Dry eye (DE) can effect on quality of life by pain, inability to perform certain activities that require prolonged attention (driving, reading,…) and productivity at work and finally effect to Q0L associated with DE. OSDI is scale questionnaire is created team to measure the quality of life related to ocular surface disease. AIM: To describe the dry eye disease according to OSDI scale and related factors of this disease. METHODS: A cross-sectional descriptive study was carried out on outpatients (≥ 16-year-old) who were examined and diagnosed with dry eyes at Vietnam National Institute Of Ophthalmology from April to July 2018. Data was collected using the OSDI questionnaire. RESULTS: The average age of participants was 44.6 years; 80.9% of patients were female; 39.9% were identified having mild dry eye. The related factors have been identified that associated with severe dry eye, including age OR = 1.03 (95%CI: 1.01-1.05, p = 0.005), binocular good vision OR = 0.11 (95%CI: 0.05-0.23; p 〈 0.0001), medical history OR = 17.09 (95%CI: 2.24-130.25; p 〈 0.0001), chronic conjunctivitis OR = 0.36 (95%CI: 0.14-0.91; p = 0.027), refractive errors OR = 0.14 (95%CI: 0.04-0.48; p 〈 0.0001), Sjogren's syndrome OR = 31.13 (95%CI: 7.08-136.76; p 〈 0.0001). CONCLUSION: Several related factors have been identified associated with severe dry eye, including: age, binocular good vision, medical history, chronic conjunctivitis, refractive errors, Sjogren's syndrome.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.377
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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  • 7
    Online Resource
    Online Resource
    Ocular Biometrics of Vietnamese Young Adults with Myopia
    Scientific Foundation SPIROSKI ; 2019
    In:  Open Access Macedonian Journal of Medical Sciences Vol. 7, No. 24 ( 2019-12-20), p. 4283-4286
    Details
    In: Open Access Macedonian Journal of Medical Sciences, Scientific Foundation SPIROSKI, Vol. 7, No. 24 ( 2019-12-20), p. 4283-4286
    Abstract: BACKGROUND: Myopia is most prevalent type of refraction error. In some Asian countries, the prevalence of myopia can be 80 – 90% in the population aged 17 – 18. AIM: To analyze the correlation between ocular biometric indices and refraction status in Vietnamese young myopes. METHODS: A prospective cross – section study was conducted in young myopes. Data on axial length, central cornea thickness, corneal topography & anterior chamber depth and spherical equivalent were collected. Independent Sample T Test and ANOVA test were used to compare between groups. The correlations between ocular biometry and myopic spherical equivalent refraction were examined by Pearson Correlation with the level of significance p 〈 0.05. RESULTS: Totally, 418 eyes from 209 patients were recruited. The average axial length, central cornea thickness, cornea refraction & anterior chamber depth were 25.68 ± 1.09 mm, 539.78 ± 32.665 µm, 43.16 ± 1.369 D, 3.30 ± 0.243 mm, respectively. The correlation between axial length and spherical equivalent refraction (SER) was high (r = - 0.742, p 〈 0.0001) while those between central cornea thickness and cornea refraction were negligible (r = - 0.107, p = 0.029; r = -0.123, p = 0.012; respectively). There was no correlation between anterior chamber depth and spherical equivalent refraction (r = 0.019, p = 0.697). CONCLUSION: Among ocular biometric indices, axial length was significantly correlated with spherical equivalent of young adult patients.
    Type of Medium: Online Resource
    ISSN: 1857-9655
    URL: Article
    DOI: 10.3889/oamjms.2019.375
    Language: Unknown
    Publisher: Scientific Foundation SPIROSKI
    Publication Date: 2019
    detail.hit.zdb_id: 3032255-8
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