In:
Frontiers in Fungal Biology, Frontiers Media SA, Vol. 3 ( 2022-7-28)
Abstract:
Fusarium verticillioides is a mycotoxigenic fungus that is a threat to food and feed safety due to its common infection of maize, a global staple crop. A proposed strategy to combat this threat is the use of biological control bacteria that can inhibit the fungus and reduce mycotoxin contamination. In this study, the effect of multiple environmental isolates of Streptomyces on F. verticillioides was examined via transcriptome analysis. The Streptomyces strains ranged from inducing no visible response to dramatic growth inhibition. Transcriptionally, F. verticillioides responded proportionally to strain inhibition with either little to no transcript changes to thousands of genes being differentially expressed. Expression changes in multiple F. verticillioides putative secondary metabolite gene clusters was observed. Interestingly, genes involved in the fusaric acid gene cluster were suppressed by inhibitory strains of Streptomyces. A F. verticillioides beta-lactamase encoding gene (FVEG_13172) was found to be highly induced by specific inhibitory Streptomyces strains and its deletion increased visible response to those strains. This study demonstrates that F. verticillioides does not have an all or nothing response to bacteria it encounters but rather a measured response that is strain specific and proportional to the strength of inhibition.
Type of Medium:
Online Resource
ISSN:
2673-6128
DOI:
10.3389/ffunb.2022.894590
DOI:
10.3389/ffunb.2022.894590.s001
DOI:
10.3389/ffunb.2022.894590.s002
DOI:
10.3389/ffunb.2022.894590.s003
DOI:
10.3389/ffunb.2022.894590.s004
DOI:
10.3389/ffunb.2022.894590.s005
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2022
detail.hit.zdb_id:
3059082-6
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