In:
The Korean Journal of Parasitology, Korean Society for Parasitology, Vol. 58, No. 2 ( 2020-04-30), p. 147-152
Abstract:
Malaria is a potent burden on public healthcare worldwide due to requiring rapid diagnosis and treatment. Nowadays, prompt diagnosis with rapid diagnostic tests (RDTs) has been widely accepted as an effective diagnostic technique in malaria-endemic countries, primarily due to their easy operation, fast output, and straightforward interpretation. The global availability and use of RDTs have gradually grown over recent decades as field-applicable diagnostic tests for the reliable confirmation of malaria infection and proper case management. This study was conducted to evaluate diagnostic performance of 3 commercially available malaria RDT kits : BIOCREDIT 〈 sup 〉 TM 〈 /sup 〉 Malaria Ag Pf(pLDH), Malaria Ag 〈 i 〉 Pf 〈 /i 〉 (pLDH/pHRPII), and Malaria Ag 〈 i 〉 Pf/Pv 〈 /i 〉 (pLDH/pLDH) (where pLDH and pHRPII stand for plasmodium lactate dehydrogenase and histidine-rich protein 2, respectively) for the specific detection of 〈 i 〉 Plasmodium falciparum 〈 /i 〉 . A total of 1,129 blood samples including 95 blood samples, confirmed as vivax malaria infection by microscopic examinations and a nested-PCR method, were tested for falciparum malaria infection. The overall sensitivity and specificity of Malaria Ag 〈 i 〉 Pf 〈 /i 〉 (pLDH/pHRPII), Malaria Ag 〈 i 〉 Pf/Pv 〈 /i 〉 (pLDH/pLDH), and 〈 i 〉 Pf 〈 /i 〉 (pLDH) for 〈 i 〉 P. falciparum 〈 /i 〉 were 99.0% and 100%, 95.8% and 100%, and 100% and 100%, respectively. It is proposed that the 3 RDT kits perform reliable level of diagnostic accuracy of detection for 〈 i 〉 P. falciparum 〈 /i 〉 parasites.
Type of Medium:
Online Resource
ISSN:
0023-4001
,
1738-0006
DOI:
10.3347/kjp.2020.58.2.147
Language:
English
Publisher:
Korean Society for Parasitology
Publication Date:
2020
detail.hit.zdb_id:
2163174-8
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