In:
Bulletin of the Chemical Society of Japan, Oxford University Press (OUP), Vol. 73, No. 5 ( 2000-05-01), p. 1213-1217
Abstract:
Novel fluorogenic coumarin derivatives appending 15-crown-5 ether as more active catalytic site were designed and synthesized for the fluorescence derivatization of carboxylic acids. From the stability constants (Ks) for complexation with metal acetates in methanol, it was found that their catalytic abilities were superior to the corresponding benzo-15-crown-5 ether type reagent. However, the reactivity of these reagents in the derivatization of lauric acid was dependent on not only the catalytic ability of the introduced crown-ether but also on the appending position of that in a reagent molecule. Furthermore, the derivatized products showed remarkably high fluorescence quantum yields of above 0.8 in methanol and acetonitrile. Allowing to hold a certain function such as catalyst in a reagent molecule should serve as a new strategy for the development of excellent analytical reagents.
Type of Medium:
Online Resource
ISSN:
0009-2673
,
1348-0634
DOI:
10.1246/bcsj.73.1213
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
2000
detail.hit.zdb_id:
2041163-7
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