In:
Retina, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 4 ( 2022-04), p. 661-668
Abstract:
To investigate predictors of early displacement of submacular hemorrhage (SMH) by simple intravitreal SF 6 gas injection. Methods: This retrospective study included 16 eyes of 16 consecutive patients (age: 74.5 ± 7.7 years; 15 men) with large SMH treated with simple intravitreal SF 6 gas before inception of subretinal tissue plasminogen activator injection at our institution. The SMH displacement was graded at 1-week posttreatment as 0, 1, or 2. Central retinal thickness, central choroidal thickness, SMH height, SMH area, disease duration, use of anticoagulant or antiplatelet drugs, and contrast-to-noise ratio (CNR) of SMH on optical coherence tomography images were recorded. Correlations between displacement grading and baseline parameter were analyzed. Results: Univariable correlation analysis revealed association of the 1-week displacement grading with the CNR ( P = 0.004; r = −0.68) and SMH height ( P = 0.03; r = −0.55). The CNR was most strongly associated with 1-week displacement on multivariable correlation analysis ( P = 0.01; β = −0.60). Conclusion: Findings of the present study showed that the CNR of SMH was a useful predictor of early displacement of large SMH after simple intravitreal SF 6 gas injection. When vitrectomy with subretinal injection of tissue plasminogen activator is difficult in patients with large SMH, with low CNR on optical coherence tomography, simple intravitreal SF 6 gas injection may be a treatment option.
Type of Medium:
Online Resource
ISSN:
0275-004X
DOI:
10.1097/IAE.0000000000003360
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2022
detail.hit.zdb_id:
2071014-8
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