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  • Monahan, Brian V.  (5)
  • 1
    Online Resource
    Online Resource
    Maad Rayan Publishing Company ; 2023
    In:  Journal of Research in Health Sciences Vol. 23, No. 2 ( 2023-06-29), p. e577-
    In: Journal of Research in Health Sciences, Maad Rayan Publishing Company, Vol. 23, No. 2 ( 2023-06-29), p. e577-
    Abstract: Background: Seasonal variation in hospitalizations for diverticulitis has a sinusoidal pattern, peaking in summer. Little is known about seasonal, regional trends, and risk factors associated with hospital admissions regarding diverticular bleeding in the United States. Study Design: Cross-sectional population database review using the healthcare cost and utilization project’s national inpatient sample. Methods: Patients that had diagnoses of diverticulitis with bleeding or diverticulosis with bleeding admitted from January 1, 2015, through December 31, 2017, were identified and stratified by month and season. Then, the potential effects of region, age, gender, race, and patient risk factors on seasonal admissions for diverticular bleeding were explored, and data were analyzed in SAS and presented in Excel using chi-square and Kruskal-Wallis for categorical and continuous variables, respectively. Results: Of the 54191 hospitalized cases for diverticular bleeding, the peak and the lowest seasons were spring and summer (25.5% vs. 24.2%, P 〈 0.0001). A significant seasonal pattern in comorbidities was also identified, and those with diabetes (P 〈 0.0001), hypertension (HTN) (P 〈 0.0001), obesity (P 〈 0.0001), and those on anticoagulants (P=0.016) all had more bleeding events in the spring. This was noted across US regions, gender, race, and age. Eventually, the southern region had the most admissions for diverticular bleeding at 40.9% (P 〈 0.0001). Conclusion: A better understanding of these seasonal and regional trends may provide a mechanism to identify a potential trigger for diverticular bleeding events. This helps identify individuals at greatest risk for hospitalization, as well as prepare hospitals to allocate supplies appropriately during the seasons.
    Type of Medium: Online Resource
    ISSN: 2228-7795 , 2228-7809
    Language: English
    Publisher: Maad Rayan Publishing Company
    Publication Date: 2023
    detail.hit.zdb_id: 2575001-X
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  • 2
    Online Resource
    Online Resource
    Maad Rayan Publishing Company ; 2023
    In:  Journal of Research in Health Sciences Vol. 23, No. 4 ( 2023-12-29), p. e00595-
    In: Journal of Research in Health Sciences, Maad Rayan Publishing Company, Vol. 23, No. 4 ( 2023-12-29), p. e00595-
    Abstract: Background: Hospitalization for peptic ulcer disease (PUD) has been described outside of North America as peaking in the fall and winter. However, no recent literature has so far investigated the seasonal fluctuations and complications of PUD in the USA. Study Design: Cross-sectional population database review. Methods: Patients with a diagnosis of either acute gastric or acute duodenal ulcers from January 1, 2015, through December 31, 2017, were identified in the Healthcare Cost and Utilization Project’s National Inpatient Sample. The proportion of admissions with either hemorrhage or perforation was determined for each season and further subdivided into geographic regions. Results: Of 18829 hospitalizations for PUD, admissions were the highest in the fall (25.9%) while being the lowest in the summer (23.9%). Complications, hemorrhage or perforation, were the highest and the lowest in the fall and spring, respectively (75.7% vs. 73.6%; P=0.060 for comparing all 4 seasons). Geographically, the West had the highest rate of peptic ulcer hemorrhage (64.5%, P=0.004), while the northeast had the highest rate of perforation (14.3%, P=0.003). Hemorrhage was more common in males, those who used aspirin, nonsteroidal anti-inflammatory drugs, or anticoagulants, and diabetics (P 〈 0.05). Perforation was less common in males, those with diabetes, obesity, or hypertension (HTN), or those using aspirin or anticoagulants (P 〈 0.05). Helicobacter pylori infection was more associated with perforation in the fall and winter months. Conclusion: Seasonal and regional trends in hospitalizations due to PUD may help identify modifiable risk factors, which can improve diagnostic and treatment outcomes for patients by allowing for more targeted identification of vulnerable populations.
    Type of Medium: Online Resource
    ISSN: 2228-7795 , 2228-7809
    Language: English
    Publisher: Maad Rayan Publishing Company
    Publication Date: 2023
    detail.hit.zdb_id: 2575001-X
    Location Call Number Limitation Availability
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  • 3
    Online Resource
    Online Resource
    Elsevier BV ; 2023
    In:  Current Problems in Surgery Vol. 60, No. 6 ( 2023-06), p. 101334-
    In: Current Problems in Surgery, Elsevier BV, Vol. 60, No. 6 ( 2023-06), p. 101334-
    Type of Medium: Online Resource
    ISSN: 0011-3840
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2052054-2
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  • 4
    Online Resource
    Online Resource
    Elsevier BV ; 2023
    In:  Current Problems in Surgery Vol. 60, No. 6 ( 2023-06), p. 101332-
    In: Current Problems in Surgery, Elsevier BV, Vol. 60, No. 6 ( 2023-06), p. 101332-
    Type of Medium: Online Resource
    ISSN: 0011-3840
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2052054-2
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  • 5
    In: Clinics in Colon and Rectal Surgery, Georg Thieme Verlag KG
    Abstract: Stage IV colorectal cancer is a prevalent disease and understanding the appropriate treatment options is important. Medical oncologic treatment remains the mainstay of treatment in cases where curative resection is not possible. Surgical intervention is indicated if the primary tumor and associated metastases are amenable to curative resection or if obstructive, bleeding, or perforative complications arise from the tumor. New endoscopic techniques can provide palliation and benefit for patients who cannot undergo surgery and may speed time to chemotherapy initiation. Recently, immunotherapy has shown promise at managing, controlling, and regressing advanced disease, in some cases converting it to curative with resection. For patients that progress while on treatment, continued medical therapy remains the mainstay of treatment. Further research into the benefits of asymptomatic primary tumor resection without curative intent needs to be performed. Colorectal cancer, and more specifically metastatic colorectal cancer, continues to have improved 1- and 5-year survival rates and likely will continue to do so over the coming months and years.
    Type of Medium: Online Resource
    ISSN: 1531-0043 , 1530-9681
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2023
    detail.hit.zdb_id: 2072321-0
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