In:
Eurosurveillance, European Centre for Disease Control and Prevention (ECDC), Vol. 24, No. 12 ( 2019-03-21)
Abstract:
In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically unrelated hospitalised children in Japan. The viruses exhibited reduced susceptibility to baloxavir but were susceptible to neuraminidase inhibitors. Only one of the two children had been treated with baloxavir. An epidemiological analysis suggests possible transmission of the PA I38T mutant A(H3N2) virus among humans.
Type of Medium:
Online Resource
ISSN:
1560-7917
DOI:
10.2807/1560-7917.ES.2019.24.12.1900170
Language:
English
Publisher:
European Centre for Disease Control and Prevention (ECDC)
Publication Date:
2019
detail.hit.zdb_id:
2059112-3
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