In:
Bioelectromagnetics, Wiley, Vol. 35, No. 2 ( 2014-02), p. 100-107
Abstract:
To evaluate duration‐ and dose‐dependent effects of continuous exposure to a 60 Hz magnetic field (MF) on the testes in mice, BALB/c male mice were exposed to a 60 Hz MF at 100 μT for 24 h a day for 2, 4, 6, or 8 weeks, and at 2, 20, or 200 μT for 24 h a day for 8 weeks. Any exposures to MF did not significantly affect body or testicular masses. However, the apoptotic cells among testicular germ cells were increased duration‐dependent at exposures of 100 μT for 6 and 8 weeks and dose‐dependent at exposures of 20 and 200 μT for 8 weeks. The number of sperm in epididymis and the diameter of seminiferous tubule decreased in mice exposed to 100 and 200 μT for 8 weeks, respectively. To induce the apoptosis of testicular germ cell in mice, the minimum dose is 20 μT at continuous exposure to a 60 Hz MF for 8 weeks and the minimum duration is 6 weeks at continuous exposure of 100 μT. Taken together, these results suggest that continuous exposure to a 60 Hz MF might affect, duration‐ and dose‐dependent biological processes including apoptotic cell death and spermatogenesis in the male reproductive system of mice. Bioelectromagnetics. 35:100–107, 2014. © 2013 Wiley Periodicals, Inc.
Type of Medium:
Online Resource
ISSN:
0197-8462
,
1521-186X
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2001228-7
SSG:
12
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