In:
Japanese Journal of Applied Physics, IOP Publishing, Vol. 44, No. 11R ( 2005-11-01), p. 8240-
Abstract:
We synthesized the peptide nanorings of cyclo [-(D-Ala-L-Gln) 3 ], cyclo [-(D-Cys-L-Gln) 3 ], cyclo [-D-Cys-L-His-D-Ala-L-Asn-Gly-L-Gln-] and cyclo [-(L-Gln) 5 ], and studied the way in which the difference in the type and/or number of component amino acid residues changes the self-assembling morphology of the nanorings on gold substrates by atomic force microscopy. The study revealed that cyclo [-(D-Ala-L-Gln) 3 ] formed nanotube bundles through inter-ring hydrogen bonds, while the nanorings of cyclo [-(D-Cys-L-Gln) 3 ] adhered to the gold surface directly due to the high affinity of thiol to gold. In contrast, a random amino acid sequence of cyclo [-D-Cys-L-His-D-Ala-L-Asn-Gly-L-Gln-] resulted in many isolated nanotubes, which were first observed in the present study. While the D,L-peptide nanotubes have very straight forms, the homo-L-peptide of cyclo [-(L-Gln) 5 ] formed interesting randomly branching nanotubes that were entwined and grew on the substrate. Scanning tunneling microscopy was also performed and high-resolution images of both the peptide nanotubes and the nanotube bundles were obtained.
Type of Medium:
Online Resource
ISSN:
0021-4922
,
1347-4065
DOI:
10.1143/JJAP.44.8240
Language:
Unknown
Publisher:
IOP Publishing
Publication Date:
2005
detail.hit.zdb_id:
218223-3
detail.hit.zdb_id:
797294-5
detail.hit.zdb_id:
2006801-3
detail.hit.zdb_id:
797295-7
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