In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 2 ( 2023-2-22), p. e0281998-
Abstract:
This study aimed to characterize patients’ symptom severity trajectories and distresses from video-assisted thoracoscopic lung resection to the first post-discharge clinic visit. Seventy-five patients undergoing thoracoscopic lung resection for diagnosed or suspected pulmonary malignancy prospectively recorded daily symptom severity on a 0–10 numeric scale using the MD Anderson Symptom Inventory until the first post-discharge clinic visit. The causes of postoperative distresses were surveyed, and symptom severity trajectories were analyzed using joinpoint regression. A rebound was defined as a statistically significant positive slope after a statistically significant negative slope. Symptom recovery was defined as symptom severity of ≤3 in two contiguous measurements. The accuracy of pain severity on days 1–5 for predicting pain recovery was determined using area under the receiver operating characteristic curves. We applied Cox proportional hazards models for multivariate analyses of the potential predictors of early pain recovery. The median age was 70 years, and females accounted for 48%. The median interval from surgery to the first post-discharge clinic visit was 20 days. Trajectories of several core symptoms including pain showed a rebound from day 3 or 4. Specifically, pain severity in patients with unrecovered pain had been higher than those with recovered pain since day 4. Pain severity on day 4 showed the highest area under the curve of 0.723 for predicting pain recovery ( P = 0.001). Multivariate analysis identified pain severity of ≤1 on day 4 as an independent predictor of early pain recovery (hazard ratio, 2.86; P = 0.0027). Duration of symptom was the leading cause of postoperative distress. Several core symptoms after thoracoscopic lung resection showed a rebound in the trajectory. Specifically, a rebound in pain trajectory may be associated with unrecovered pain; pain severity on day 4 may predict early pain recovery. Further clarification of symptom severity trajectories is essential for patient-centered care.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0281998
DOI:
10.1371/journal.pone.0281998.g001
DOI:
10.1371/journal.pone.0281998.g002
DOI:
10.1371/journal.pone.0281998.g003
DOI:
10.1371/journal.pone.0281998.g004
DOI:
10.1371/journal.pone.0281998.g005
DOI:
10.1371/journal.pone.0281998.g006
DOI:
10.1371/journal.pone.0281998.t001
DOI:
10.1371/journal.pone.0281998.t002
DOI:
10.1371/journal.pone.0281998.t003
DOI:
10.1371/journal.pone.0281998.s001
DOI:
10.1371/journal.pone.0281998.s002
DOI:
10.1371/journal.pone.0281998.s003
DOI:
10.1371/journal.pone.0281998.s004
DOI:
10.1371/journal.pone.0281998.s005
DOI:
10.1371/journal.pone.0281998.s006
DOI:
10.1371/journal.pone.0281998.s007
DOI:
10.1371/journal.pone.0281998.r001
DOI:
10.1371/journal.pone.0281998.r002
DOI:
10.1371/journal.pone.0281998.r003
DOI:
10.1371/journal.pone.0281998.r004
DOI:
10.1371/journal.pone.0281998.r005
DOI:
10.1371/journal.pone.0281998.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3
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