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  • 1
    In: Journal of Pharmaceutical Research International, Sciencedomain International, ( 2021-09-15), p. 466-474
    Abstract: Background: Resin-dentin bonds are less durable than enamel as they rely on organic part for mineralisation. Bond denaturation mainly takes place because of hydrolysis of polymerized resin or degradation of water-rich, resin-sparse collagen by collagenolytic endogenous matrix metalloproteinase and cysteine cathepsins. Hence, this limited stability of dentin bonding tenaciously reduces the longevity of tooth-coloured restorations. One of the strategies adopted to encounter this shortcoming is to induce biomimetic remineralisation. Aim: To assess the microtensile bond strength of resin composites to dentin following remineralisation using an experimental paste containing nano-hydroxyapatite (nHAp) and biomimetic analogues, Poly Acrylic Acid (PAA) and Sodium Tri Polyphosphate (STPP). Methodology: Nine intact freshly extracted third molar were used for this study to evaluate the microtensile bond strength after treating with three different groups; Group I with paste containing nano hydroxyapatite nHAp Group II paste containing nHAp and non-collagenous protein analogues such as (Polyacrcrylic acid and Sodium tripolyphosphate) and the control groups containing adhesive and resin composite with no additional treatment. The samples were observed over a period of 24 hours and 1 week the inter group data analysis was done using ANOVA and paired sample t test and the intra-group data analysis over period of 24 hours the post HOC Bonferroni test was used for the statistical analysis. Results: After 24 hours the group with nHAp group showed highest value for microtensile bond strength among other groups, however after one week the group with nHAp +NCP analogues(PAA+STPP) showed highest value for microtensile bond. Conclusion: The treatment with the experimental paste [nHAp+NCP] analogues (PAA+STPP)] can bring about remineralisation to improve bonding to dentin.
    Type of Medium: Online Resource
    ISSN: 2456-9119
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2021
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  • 2
    In: Research Journal of Pharmacy and Technology, A and V Publications
    Abstract: The world is undergoing its biggest health crisis named coronavirus disease, which is associated with increased proinflammatory cytokine storm, which ultimately leads to various medical complications including acute respiratory distress syndrome. The treatment protocol was always controversial due to the excessive use of corticosteroids in aggressive pneumonia and associated hyperinflammatory conditions.The excessive use, misuse, and rampant use of steroids may lead to various coinfection like mucormycosis which is referred to as black fungus that manifests within the skin and also affects the lungs and brain which may be more fatal. It is necessary to have early diagnosis and management to tackle the severity of post covid coinfection.
    Type of Medium: Online Resource
    ISSN: 0974-360X , 0974-3618
    Language: English
    Publisher: A and V Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2846942-2
    SSG: 15,3
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  • 3
    Online Resource
    Online Resource
    Rajiv Gandhi University of Health Sciences ; 2022
    In:  RGUHS Journal of Medical Sciences Vol. 12, No. 2 ( 2022)
    In: RGUHS Journal of Medical Sciences, Rajiv Gandhi University of Health Sciences, Vol. 12, No. 2 ( 2022)
    Abstract: The novel Coronavirus disease 2019 has led to a global pandemic at a scale that was not experienced by the human race for several decades. The evidence suggests that respiratory droplets are the common route of transmission for Coronavirus. Several public health agencies have recommended the wearing of masks in public settings to curtail the virus spread. Regardless of the debates in the medical community and the global mask availability shortage more countries and regions are moving forward with recommendations or mandates to wear masks in public. However as a result of extended use reuse and reprocessing of single-use masks and respirators several dermatological psychological and other health hazards are being increasingly reported. This review aims to comprehensively assess the various ill-effects of long-term use of facemask in the general population.nbsp
    Type of Medium: Online Resource
    ISSN: 2231-1947 , 2581-7248
    URL: Issue
    Language: English
    Publisher: Rajiv Gandhi University of Health Sciences
    Publication Date: 2022
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